{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:56:14Z","timestamp":1761897374065,"version":"3.40.5"},"reference-count":140,"publisher":"American Society for Microbiology","issue":"24","license":[{"start":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T00:00:00Z","timestamp":1605744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI092825-09"],"award-info":[{"award-number":["R01AI092825-09"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2020,11,19]]},"abstract":"<jats:p>\n            Pathogenic\n            <jats:italic>Vibrio<\/jats:italic>\n            species use many different approaches to subvert, attack, and undermine the host response. The toxins they produce are often responsible for the devastating effects associated with their diseases. These toxins target a variety of host proteins, which leads to deleterious effects, including dissolution of cell organelle integrity and inhibition of protein secretion. Becoming increasingly prevalent as cofactors for\n            <jats:italic>Vibrio<\/jats:italic>\n            toxins are proteins of the small GTPase families.\n          <\/jats:p>","DOI":"10.1128\/jb.00278-20","type":"journal-article","created":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T14:21:59Z","timestamp":1599229319000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Cross-Kingdom Activation of\n            <i>Vibrio<\/i>\n            Toxins by ADP-Ribosylation Factor Family GTPases"],"prefix":"10.1128","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7081-4208","authenticated-orcid":false,"given":"Alfa","family":"Herrera","sequence":"first","affiliation":[{"name":"Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3274-7611","authenticated-orcid":false,"given":"Karla J. F.","family":"Satchell","sequence":"additional","affiliation":[{"name":"Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.VE-0002-2014"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00248-012-0168-x"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.011442598"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12451"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aat8335"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1113398"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M605275200"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004944"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2003.09.012"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2009.10.066"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E18-12-0820"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1910"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.23.090506.123209"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3117"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/1-4020-2593-9"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00928458"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)68474-1"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.10.12.6690"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)52288-2"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-2273com"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200512057"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0962-8924(99)01699-2"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1957170"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.14.6408"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0968-0004(99)01429-2"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200806041"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2010.04.005"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1080\/21541248.2017.1299271"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0968-0004(98)01224-9"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/384481a0"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/32210"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.31.19792"},{"key":"e_1_3_1_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2010.07.002"},{"key":"e_1_3_1_35_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500095102"},{"key":"e_1_3_1_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1991.tb16271.x"},{"key":"e_1_3_1_37_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E11-01-0082"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90323-i"},{"key":"e_1_3_1_39_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.8290961"},{"key":"e_1_3_1_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(00)81540-8"},{"key":"e_1_3_1_41_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.c901019199"},{"key":"e_1_3_1_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1119"},{"key":"e_1_3_1_43_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2234055100"},{"key":"e_1_3_1_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvv088"},{"key":"e_1_3_1_45_2","doi-asserted-by":"publisher","DOI":"10.3109\/10409238.2015.1085827"},{"key":"e_1_3_1_46_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M000024200"},{"key":"e_1_3_1_47_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.01-11-0547"},{"key":"e_1_3_1_48_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.01-12-0579"},{"key":"e_1_3_1_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.04.061"},{"key":"e_1_3_1_50_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0854.2004.00225.x"},{"key":"e_1_3_1_51_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.15.8607"},{"key":"e_1_3_1_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-017-2949-2"},{"key":"e_1_3_1_53_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.2.1069"},{"key":"e_1_3_1_54_2","doi-asserted-by":"publisher","DOI":"10.3892\/or.2017.5388"},{"key":"e_1_3_1_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2008.10.031"},{"key":"e_1_3_1_56_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5744"},{"key":"e_1_3_1_57_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.3.1238"},{"key":"e_1_3_1_58_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007795"},{"key":"e_1_3_1_59_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.123.6.1365"},{"key":"e_1_3_1_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0014-5793(99)01543-4"},{"key":"e_1_3_1_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/360350a0"},{"key":"e_1_3_1_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)50311-8"},{"key":"e_1_3_1_63_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.11.4.1241"},{"key":"e_1_3_1_64_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.149.1.81"},{"key":"e_1_3_1_65_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301632200"},{"key":"e_1_3_1_66_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.11.11.3723"},{"key":"e_1_3_1_67_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.10.8.2787"},{"key":"e_1_3_1_68_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.142.2.391"},{"key":"e_1_3_1_69_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.123.3.561"},{"key":"e_1_3_1_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90277-w"},{"key":"e_1_3_1_71_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E17-11-0622"},{"key":"e_1_3_1_72_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E13-04-0197"},{"key":"e_1_3_1_73_2","doi-asserted-by":"publisher","DOI":"10.1247\/csf.12015"},{"key":"e_1_3_1_74_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e04-12-1042"},{"key":"e_1_3_1_75_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.7.4141"},{"key":"e_1_3_1_76_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi0107391"},{"key":"e_1_3_1_77_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2001.5330"},{"key":"e_1_3_1_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(03)00603-2"},{"key":"e_1_3_1_79_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200112092"},{"key":"e_1_3_1_80_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.128.6.1003"},{"key":"e_1_3_1_81_2","doi-asserted-by":"publisher","DOI":"10.1038\/362648a0"},{"key":"e_1_3_1_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)42277-0"},{"key":"e_1_3_1_83_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002092"},{"key":"e_1_3_1_84_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06097"},{"key":"e_1_3_1_85_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.045849"},{"key":"e_1_3_1_86_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06928"},{"key":"e_1_3_1_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2010.09.002"},{"key":"e_1_3_1_88_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R300026200"},{"key":"e_1_3_1_89_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.134.4.935"},{"key":"e_1_3_1_90_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.17.4973"},{"key":"e_1_3_1_91_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.32.19977"},{"key":"e_1_3_1_92_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.17.5445"},{"key":"e_1_3_1_93_2","doi-asserted-by":"publisher","DOI":"10.1038\/372704a0"},{"key":"e_1_3_1_94_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi962252b"},{"key":"e_1_3_1_95_2","doi-asserted-by":"publisher","DOI":"10.7176\/JMPB\/55-03"},{"key":"e_1_3_1_96_2","doi-asserted-by":"publisher","DOI":"10.1038\/351371a0"},{"key":"e_1_3_1_97_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00651a011"},{"key":"e_1_3_1_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)50491-9"},{"key":"e_1_3_1_99_2","doi-asserted-by":"publisher","DOI":"10.3390\/toxins2030310"},{"key":"e_1_3_1_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(96)01447-0"},{"key":"e_1_3_1_101_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi971383p"},{"key":"e_1_3_1_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2003.10.002"},{"key":"e_1_3_1_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0076-6879(83)96054-8"},{"key":"e_1_3_1_104_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cb.02.110186.002135"},{"key":"e_1_3_1_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)44426-7"},{"key":"e_1_3_1_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)92963-7"},{"key":"e_1_3_1_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(90)90076-9"},{"key":"e_1_3_1_108_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.8.3307"},{"key":"e_1_3_1_109_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2592"},{"key":"e_1_3_1_110_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.8073283"},{"key":"e_1_3_1_111_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.66.1.639"},{"key":"e_1_3_1_112_2","doi-asserted-by":"publisher","DOI":"10.3390\/toxins2040632"},{"key":"e_1_3_1_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90446-6"},{"key":"e_1_3_1_114_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2003.11.005"},{"key":"e_1_3_1_115_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)57489-0"},{"key":"e_1_3_1_116_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.15.5139"},{"key":"e_1_3_1_117_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)37110-8"},{"key":"e_1_3_1_118_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115197"},{"key":"e_1_3_1_119_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftv092"},{"key":"e_1_3_1_120_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01806-10"},{"key":"e_1_3_1_121_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1905095116"},{"key":"e_1_3_1_122_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.13133"},{"key":"e_1_3_1_123_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00570-15"},{"key":"e_1_3_1_124_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy590"},{"key":"e_1_3_1_125_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12568"},{"key":"e_1_3_1_126_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.01.040"},{"key":"e_1_3_1_127_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1902922116"},{"key":"e_1_3_1_128_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00064"},{"key":"e_1_3_1_129_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1067025"},{"key":"e_1_3_1_130_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2011.01631.x"},{"key":"e_1_3_1_131_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.01.040"},{"key":"e_1_3_1_132_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09593"},{"key":"e_1_3_1_133_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.09.039"},{"key":"e_1_3_1_134_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410820200"},{"key":"e_1_3_1_135_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.06.050"},{"key":"e_1_3_1_136_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)50140-5"},{"key":"e_1_3_1_137_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2014.10.006"},{"key":"e_1_3_1_138_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M413090200"},{"key":"e_1_3_1_139_2","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kve043"},{"key":"e_1_3_1_140_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature02197"},{"key":"e_1_3_1_141_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20084"}],"container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.00278-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.00278-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T17:58:09Z","timestamp":1627581489000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JB.00278-20"}},"subtitle":[],"editor":[{"given":"William","family":"Margolin","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,11,19]]},"references-count":140,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2020,11,19]]}},"alternative-id":["10.1128\/JB.00278-20"],"URL":"https:\/\/doi.org\/10.1128\/jb.00278-20","relation":{},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"type":"print","value":"0021-9193"},{"type":"electronic","value":"1098-5530"}],"subject":[],"published":{"date-parts":[[2020,11,19]]},"assertion":[{"value":"2020-11-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}