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The ResD response regulator transcription factor has been implicated in the regulation of virulence factors in a number of gram-positive species, including<jats:italic>Bacillus anthracis<\/jats:italic>. The precise deletions of<jats:italic>resD<\/jats:italic>and<jats:italic>resE<\/jats:italic>in<jats:italic>B. anthracis<\/jats:italic>that retained the classical respiratory phenotypes did not affect the expression of the gene for the protective antigen of the anthrax toxin,<jats:italic>pagA<\/jats:italic>, or that of the toxin regulator,<jats:italic>atxA<\/jats:italic>. The results indicate that the loss of ResDE-controlled respiratory capacity does not affect the synthesis of anthrax toxin.<\/jats:p>","DOI":"10.1128\/jb.00312-08","type":"journal-article","created":{"date-parts":[[2008,6,7]],"date-time":"2008-06-07T00:55:33Z","timestamp":1212800133000},"page":"5522-5525","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":16,"title":["Virulence Gene Expression Is Independent of ResDE-Regulated Respiration Control in<i>Bacillus anthracis<\/i>"],"prefix":"10.1128","volume":"190","author":[{"given":"Adam C.","family":"Wilson","sequence":"first","affiliation":[{"name":"Division of Cellular Biology, Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"Hoch","sequence":"additional","affiliation":[{"name":"Division of Cellular Biology, Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Perego","sequence":"additional","affiliation":[{"name":"Division of Cellular Biology, Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1046\/j.1365-2958.1998.01122.x","volume":"30","year":"1998","unstructured":"Birkey, S. 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