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In addition, research on\n                      <jats:italic toggle=\"yes\">S. mutans<\/jats:italic>\n                      has greatly advanced key areas of microbiology, establishing the organism as a notably useful model for understanding the biology of other streptococcal species, as well as Gram-positive bacteria more broadly. In this piece, we provide a retrospective of how\n                      <jats:italic toggle=\"yes\">S. mutans<\/jats:italic>\n                      has served this dual role, highlighting specific areas that have benefited most from\n                      <jats:italic toggle=\"yes\">S. mutans<\/jats:italic>\n                      \u2013driven discoveries. We close by outlining emerging areas of\n                      <jats:italic toggle=\"yes\">S. mutans<\/jats:italic>\n                      research that are likely to influence future breakthroughs in both oral health science and basic microbiology.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/jb.00555-25","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T14:00:27Z","timestamp":1770991227000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["A\n                    <i>Streptococcus mutans<\/i>\n                    retrospective: from oral pathogen to bacterial paradigm"],"prefix":"10.1128","volume":"208","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9269-2707","authenticated-orcid":true,"given":"Lin","family":"Zeng","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02y3ad647","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Oral Biology, University of Florida College of Dentistry","place":["Gainesville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6615-7348","authenticated-orcid":true,"given":"Jacqueline","family":"Abranches","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02y3ad647","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Oral Biology, University of Florida College of Dentistry","place":["Gainesville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0791-5863","authenticated-orcid":true,"given":"Jos\u00e9 A.","family":"Lemos","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02y3ad647","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Oral Biology, University of Florida College of Dentistry","place":["Gainesville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/432767"},{"key":"e_1_3_2_3_2","first-page":"406","volume-title":"The micro-organisms of the human mouth: the local and general diseases which are caused by them","author":"Miller WD","year":"1890","unstructured":"Miller WD. 1890. 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