{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:12:18Z","timestamp":1790838738475,"version":"4.1.0"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2022,4,19]]},"abstract":"<jats:p>\n            <jats:named-content content-type=\"genus-species\">Leptospira interrogans<\/jats:named-content>\n            , the cause of the zoonotic infection leptospirosis, is found in soil and water contaminated with animal urine.\n            <jats:named-content content-type=\"genus-species\">L. interrogans<\/jats:named-content>\n            survives in complex environments with the aid of 12 chemoreceptors, none of which has been explicitly studied. In this study, we characterized the first\n            <jats:named-content content-type=\"genus-species\">L. interrogans<\/jats:named-content>\n            chemoreceptor,\n            <jats:italic>Li<\/jats:italic>\n            Aer2, and reported its unique characteristics.\n            <jats:italic>Li<\/jats:italic>\n            Aer2 is membrane-bound, has three cytoplasmic PAS-heme domains that each bound hexacoordinate\n            <jats:italic>b<\/jats:italic>\n            -type heme and O\n            <jats:sub>2<\/jats:sub>\n            turned\n            <jats:italic>Li<\/jats:italic>\n            Aer2 signaling off.\n          <\/jats:p>","DOI":"10.1128\/jb.00567-21","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T13:01:34Z","timestamp":1647867694000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Leptospira interrogans Aer2: an Unusual Membrane-Bound PAS-Heme Oxygen Sensor"],"prefix":"10.1128","volume":"204","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3872-0236","authenticated-orcid":true,"given":"Emilie","family":"Orillard","sequence":"first","affiliation":[{"name":"Division of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8072-2745","authenticated-orcid":true,"given":"Kylie J.","family":"Watts","sequence":"additional","affiliation":[{"name":"Division of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz988"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02288-12"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.5.2270-2272.1993"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2020.10.013"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07477.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13978"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsle\/fnu054"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2006.05218.x"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14612"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073923"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2000724"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15736-5"},{"key":"e_1_3_3_14_2","volume-title":"Comparative genomics of the microbial chemotaxis system. 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