{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:08:41Z","timestamp":1785424121702,"version":"3.56.0"},"reference-count":150,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100008982","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NSF 231861"],"award-info":[{"award-number":["NSF 231861"]}],"id":[{"id":"10.13039\/501100008982","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI064693"],"award-info":[{"award-number":["AI064693"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U19AI162568"],"award-info":[{"award-number":["U19AI162568"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2026,4,23]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Over the past 30 years, the study of\n                      <jats:italic toggle=\"yes\">Mycobacterium tuberculosis<\/jats:italic>\n                      has become a vibrant field that supports basic investigation into mycobacteria, wide-ranging studies of\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      pathogenesis, and drug and therapeutic development. In this minireview, we highlight the multiple ways in which\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      is a model.\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      has emerged as a model for prokaryotic biology, revealing basic mechanisms of gene expression, genomic integrity, and mutagenesis that expand prokaryotic dogmas established in earlier model organisms. Next, we highlight the experimental systems used to model\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      human infection. As an obligate human pathogen, all attempts to understand the pathogenesis of TB disease seek to mimic the human infection, and a variety of systems have emerged from our field. Finally, we highlight that the\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      field is a model for a community-driven scientific approach to a pressing global health problem for which commercial interest is limited. Our field has taken on the challenge of drug and diagnostic development, based on a foundation of expanding knowledge of basic\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      biology, by working through academic and public\/private partnerships, to make meaningful progress in therapeutics and diagnostics. Altogether, we present the\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      field as a model for the development of a productive community that spans basic, translational, and therapeutic research, supported by public and philanthropic funding, to ultimately positively impact the treatment of human TB and the advancement of our knowledge base of microbiology and microbial pathogenesis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/jb.00609-25","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:00:27Z","timestamp":1773666027000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["<i>Mycobacterium tuberculosis<\/i>\n                    as a model system"],"prefix":"10.1128","volume":"208","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5792-5692","authenticated-orcid":false,"given":"Emilee","family":"Barnard","sequence":"first","affiliation":[{"name":"Immunology Program, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute","place":["New York, USA"]},{"id":[{"id":"https:\/\/ror.org\/02r109517","id-type":"ROR","asserted-by":"publisher"}],"name":"BCMB Graduate Program, Weill Cornell Medicine","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8462-9217","authenticated-orcid":false,"given":"M. Maria","family":"Elgrail","sequence":"additional","affiliation":[{"name":"Immunology Program, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Fay","sequence":"additional","affiliation":[{"name":"Immunology Program, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3777-0546","authenticated-orcid":false,"given":"Yaprak","family":"Ozakman","sequence":"additional","affiliation":[{"name":"Immunology Program, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7918-5164","authenticated-orcid":true,"given":"Michael S.","family":"Glickman","sequence":"additional","affiliation":[{"name":"Immunology Program, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute","place":["New York, USA"]},{"id":[{"id":"https:\/\/ror.org\/02r109517","id-type":"ROR","asserted-by":"publisher"}],"name":"BCMB Graduate Program, Weill Cornell Medicine","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00030-23"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00337-22"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00047-25"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.171.6.3046-3052.1989"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.171.7.3641-3649.1989"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.163.3.870-876.1985"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2665076"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.25.100171.002253"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-2895-7_48"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/br.40.4.869-907.1976"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2009.09.002"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/31159"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001107"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.181001"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1074584"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw149"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099824"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M401841200"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb915"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00332-07"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1631908"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07463.x"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01832-14"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01540-14"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1368-7646(03)00041-4"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2012.06.065"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fux011"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ddmec.2010.08.002"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.03199.x"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.05.073"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adq9054"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab1169"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/pnasnexus\/pgae555"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2018.07.037"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/tx0600043"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2006792117"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","unstructured":"Cafiero JH Xiao J Lepori I Rapiejko AR Reddy M Roberts LA Siegrist MS Sacchettini JC Shell SS. 2025. Mycobacterium tuberculosis MutT4 is an RNA pyrophosphohydrolase that forms biomolecular condensates and sensitizes mRNAs to degradation. bioRxiv. doi:10.1101\/2025.05.13.653832","DOI":"10.1101\/2025.05.13.653832"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaf842"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00314-24"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00270-8"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1002614107"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32022-8"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2301394120"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.03762-24"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-25055-y"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.83094"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1027"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku752"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.4061\/2010\/260512"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.01038.x"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2009.00170.x"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14246"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells10061314"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2009.192"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(00)81515-9"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90114-0"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1069595"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkae209"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00931-14"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2011.05.002"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms16072"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.04.041"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07206-5"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2013706117"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.22520"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz449"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw577"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv078"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1900176116"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2023.104724"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1231"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2006.00040.x"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2009.07479.x"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.4.895-902.2004"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-032221-024032"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.181.2.469-476.1999"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11062"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12337"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02525.x"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.20.6119-6125.2001"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.3.1733-1745.2004"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01212.x"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis102"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2009.07008.x"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1369-5274(99)80024-1"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03739.x"},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2016.103"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3664"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.54.1.499"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-022-01313-7"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1128\/msystems.00289-24"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.MGM2-0010-2013"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(01)00236-7"},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-024-01683-0"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.5588\/ijtldopen.24.0336"},{"key":"e_1_3_2_97_2","unstructured":"Koch R. 2010. Die aetiologie der tuberkulose"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1970.102.6.937"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.51.5.743"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.45.2.209"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","unstructured":"Naqvi KF Guo Y Sapkota D Lu P Wang S Dias BRS Ektnitphong VA Martin AE Evers BM Lu LL Ouyang H Bourouiba L Shiloh MU. 2025. Airflow determines natural airborne transmission of tuberculosis in a guinea pig model. bioRxiv:2025.10.27.684829. doi:10.1101\/2025.10.27.684829","DOI":"10.1101\/2025.10.27.684829"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.026"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0171-2985(11)80459-6"},{"key":"e_1_3_2_104_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.6.2249"},{"key":"e_1_3_2_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90001-2"},{"key":"e_1_3_2_106_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2567.1998.00419.x"},{"key":"e_1_3_2_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2020.10.003"},{"key":"e_1_3_2_108_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature03419"},{"key":"e_1_3_2_109_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.67290"},{"key":"e_1_3_2_110_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202722"},{"key":"e_1_3_2_111_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI42796"},{"key":"e_1_3_2_112_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063331"},{"key":"e_1_3_2_113_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep21522"},{"key":"e_1_3_2_114_2","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.111.132639"},{"key":"e_1_3_2_115_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01516-16"},{"key":"e_1_3_2_116_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02791-19"},{"key":"e_1_3_2_117_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.74419"},{"key":"e_1_3_2_118_2","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.020867"},{"key":"e_1_3_2_119_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20210332"},{"key":"e_1_3_2_120_2","doi-asserted-by":"publisher","unstructured":"Vinette V Castro A Kim H Trujillo C Xie M Gengenbacher M Ioerger TR Ehrt S. 2025. Interstitial macrophages prevent tuberculosis relapse by restricting Mycobacterium tuberculosis immune evasion. bioRxiv:2025.08.27.672444. doi:10.1101\/2025.08.27.672444","DOI":"10.1101\/2025.08.27.672444"},{"key":"e_1_3_2_121_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a018564"},{"key":"e_1_3_2_122_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.02850-14"},{"key":"e_1_3_2_123_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2012.00536.x"},{"key":"e_1_3_2_124_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.10.5831-5844.2003"},{"key":"e_1_3_2_125_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00592-09"},{"key":"e_1_3_2_126_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3412"},{"key":"e_1_3_2_127_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-020-00262-8"},{"key":"e_1_3_2_128_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00776-17"},{"key":"e_1_3_2_129_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20241571"},{"key":"e_1_3_2_130_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1817-8"},{"key":"e_1_3_2_131_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-018-0231-6"},{"key":"e_1_3_2_132_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1315-z"},{"key":"e_1_3_2_133_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2025.01.023"},{"key":"e_1_3_2_134_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio884"},{"key":"e_1_3_2_135_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1106753"},{"key":"e_1_3_2_136_2","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2023113687"},{"key":"e_1_3_2_137_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-3004-3"},{"key":"e_1_3_2_138_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3262"},{"key":"e_1_3_2_139_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-20989-8"},{"key":"e_1_3_2_140_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1164571"},{"key":"e_1_3_2_141_2","doi-asserted-by":"publisher","DOI":"10.1038\/35016103"},{"key":"e_1_3_2_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2018.04.008"},{"key":"e_1_3_2_143_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01463-09"},{"key":"e_1_3_2_144_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.11.4131-4137.2001"},{"key":"e_1_3_2_145_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0498-359"},{"key":"e_1_3_2_146_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.12.5512-5516.2004"},{"key":"e_1_3_2_147_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00543-2016"},{"key":"e_1_3_2_148_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00034-13"},{"key":"e_1_3_2_149_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.103.2.325"},{"key":"e_1_3_2_150_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5419.1520"},{"key":"e_1_3_2_151_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02742-2"}],"container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jb.00609-25","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jb.00609-25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T13:02:11Z","timestamp":1776949331000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jb.00609-25"}},"subtitle":[],"editor":[{"given":"George","family":"O'Toole","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,4,23]]},"references-count":150,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,23]]}},"alternative-id":["10.1128\/jb.00609-25"],"URL":"https:\/\/doi.org\/10.1128\/jb.00609-25","relation":{},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"value":"0021-9193","type":"print"},{"value":"1098-5530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,23]]},"assertion":[{"value":"2026-03-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00609-25"}}