{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:53:17Z","timestamp":1791247997839,"version":"4.1.0"},"reference-count":70,"publisher":"American Society for Microbiology","issue":"22","license":[{"start":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T00:00:00Z","timestamp":1384473600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2013,11,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Extraintestinal pathogenic\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Escherichia coli<\/jats:named-content>\n            (ExPEC) is capable of colonizing outside of the intestinal tract and evolving into a systemic infection. Avian pathogenic\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">E. coli<\/jats:named-content>\n            (APEC) is a member of the ExPEC group and causes avian colibacillosis. Transfer-mRNA-small protein B (tmRNA-SmpB)-mediated\n            <jats:italic>trans<\/jats:italic>\n            -translation is a bacterial translational control system that directs the modification and degradation of proteins, the biosynthesis of which has stalled or has been interrupted, facilitating the rescue of ribosomes stalled at the 3\u2032 ends of defective mRNAs that lack a stop codon. We found that disruption of one, or both, of the\n            <jats:italic>smpB<\/jats:italic>\n            or\n            <jats:italic>ssrA<\/jats:italic>\n            genes significantly decreased the virulence of the APEC strain E058, as assessed by chicken infection assays. Furthermore, the mutants were obviously attenuated in colonization and persistence assays. The results of quantitative real-time reverse transcription-PCR analysis indicated that the transcription levels of the transcriptional regulation gene\n            <jats:italic>rfaH<\/jats:italic>\n            and the virulence genes\n            <jats:italic>kpsM<\/jats:italic>\n            ,\n            <jats:italic>chuA<\/jats:italic>\n            , and\n            <jats:italic>iss<\/jats:italic>\n            were significantly decreased compared to those of the wild-type strain. Macrophage infection assays showed that the mutant strains reduced the replication and\/or survival ability in the macrophage HD11 cell line compared to that of the parent strain, E058. However, no significant differences were observed in ingestion by macrophages and in chicken serum resistance between the mutant and the wild-type strains. These data indicate that the tmRNA-SmpB system is important in the pathogenesis of APEC O2 strain E058.\n          <\/jats:p>","DOI":"10.1128\/jb.00628-13","type":"journal-article","created":{"date-parts":[[2013,9,7]],"date-time":"2013-09-07T05:34:47Z","timestamp":1378532087000},"page":"5064-5071","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":24,"title":["The Transfer-Messenger RNA-Small Protein B System Plays a Role in Avian Pathogenic Escherichia coli Pathogenicity"],"prefix":"10.1128","volume":"195","author":[{"given":"Xiaohui","family":"Mu","sequence":"first","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixia","family":"Huan","sequence":"additional","affiliation":[{"name":"College of Life Science, Huaiyin Normal University, Huaian, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqing","family":"Xu","sequence":"additional","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Gao","sequence":"additional","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Xiong","sequence":"additional","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxia","family":"Gao","sequence":"additional","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Gao","sequence":"additional","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiufan","family":"Liu","sequence":"additional","affiliation":[{"name":"Animal Infectious Disease Laboratory, Ministry of Agriculture, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","first-page":"157","article-title":"Pathogenic diversity of Escherichia coli and the emergence of \u2018exotic' islands in the gene stream","volume":"30","author":"Dozois CM","year":"1999","unstructured":"DozoisCMCurtissRIII. 1999. Pathogenic diversity of Escherichia coli and the emergence of \u2018exotic' islands in the gene stream. Vet. Res. 30:157\u2013179.","journal-title":"Vet. Res."},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/nrmicro818","article-title":"Pathogenic Escherichia coli.","volume":"2","author":"Kaper JB","year":"2004","unstructured":"KaperJBNataroJPMobleyHL. 2004. Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2:123\u2013140.","journal-title":"Nat. Rev. Microbiol."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/315418"},{"key":"e_1_3_3_5_2","first-page":"299","article-title":"Avian pathogenic Escherichia coli (APEC)","volume":"30","author":"Dho-Moulin M","year":"1999","unstructured":"Dho-MoulinMFairbrotherJM. 1999. Avian pathogenic Escherichia coli (APEC). Vet. Res. 30:299\u2013316.","journal-title":"Vet. Res."},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3390\/ijerph7010089","article-title":"Avian colibacillosis and salmonellosis: a closer look at epidemiology, pathogenesis, diagnosis, control and public health concerns","volume":"7","author":"Lutful Kabir SM","year":"2010","unstructured":"Lutful KabirSM. 2010. Avian colibacillosis and salmonellosis: a closer look at epidemiology, pathogenesis, diagnosis, control and public health concerns. Int. J. Environ. Res. Public Health 7:89\u2013114.","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1139\/m92-115","article-title":"Escherichia coli serotyping and disease in man and animals","volume":"38","author":"Orskov F","year":"1992","unstructured":"OrskovFOrskovI. 1992. Escherichia coli serotyping and disease in man and animals. Can. J. Microbiol. 38:699\u2013704.","journal-title":"Can. J. Microbiol."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02421-09"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.4.1.80"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.024869-0"},{"key":"e_1_3_3_11_2","doi-asserted-by":"crossref","first-page":"9223","DOI":"10.1073\/pnas.91.20.9223","article-title":"A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli.","volume":"91","author":"Komine Y","year":"1994","unstructured":"KomineYKitabatakeMYokogawaTNishikawaKInokuchiH. 1994. A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 91:9223\u20139227.","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1126\/science.271.5251.990","article-title":"Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA","volume":"271","author":"Keiler KC","year":"1996","unstructured":"KeilerKCWallerPRSauerRT. 1996. Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA. Science 271:990\u2013993.","journal-title":"Science"},{"key":"e_1_3_3_13_2","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1093\/emboj\/18.13.3793","article-title":"SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA)","volume":"18","author":"Karzai AW","year":"1999","unstructured":"KarzaiAWSusskindMMSauerRT. 1999. SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA). EMBO J. 18:3793\u20133799.","journal-title":"EMBO J."},{"key":"e_1_3_3_14_2","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/j.1365-2958.2005.04832.x","article-title":"Ribosome rescue: tmRNA tagging activity and capacity in Escherichia coli.","volume":"58","author":"Moore SD","year":"2005","unstructured":"MooreSDSauerRT. 2005. Ribosome rescue: tmRNA tagging activity and capacity in Escherichia coli. Mol. Microbiol. 58:456\u2013466.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_15_2","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/nature11006","article-title":"The complex of tmRNA-SmpB and EF-G on translocating ribosomes","volume":"485","author":"Ramrath DJ","year":"2012","unstructured":"RamrathDJYamamotoHRotherKWittekDPechMMielkeTLoerkeJScheererPIvanovPTeraokaYShpanchenkoONierhausKHSpahnCM. 2012. The complex of tmRNA-SmpB and EF-G on translocating ribosomes. Nature 485:526\u2013529.","journal-title":"Nature"},{"key":"e_1_3_3_16_2","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1017\/S135583829999101X","article-title":"Aminoacylated tmRNA from Escherichia coli interacts with prokaryotic elongation factor Tu","volume":"5","author":"Rudinger-Thirion J","year":"1999","unstructured":"Rudinger-ThirionJGiegeRFeldenB. 1999. Aminoacylated tmRNA from Escherichia coli interacts with prokaryotic elongation factor Tu. RNA 5:989\u2013992.","journal-title":"RNA"},{"key":"e_1_3_3_17_2","doi-asserted-by":"crossref","first-page":"6612","DOI":"10.1093\/emboj\/19.23.6612","article-title":"Binding and cross-linking of tmRNA to ribosomal protein S1, on and off the Escherichia coli ribosome","volume":"19","author":"Wower IK","year":"2000","unstructured":"WowerIKZwiebCWGuvenSAWowerJ. 2000. Binding and cross-linking of tmRNA to ribosomal protein S1, on and off the Escherichia coli ribosome. EMBO J. 19:6612\u20136621.","journal-title":"EMBO J."},{"key":"e_1_3_3_18_2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1146\/annurev.biochem.75.103004.142733","article-title":"The tmRNA system for translational surveillance and ribosome rescue","volume":"76","author":"Moore SD","year":"2007","unstructured":"MooreSDSauerRT. 2007. The tmRNA system for translational surveillance and ribosome rescue. Annu. Rev. Biochem. 76:101\u2013124.","journal-title":"Annu. Rev. Biochem."},{"key":"e_1_3_3_19_2","doi-asserted-by":"crossref","first-page":"D104","DOI":"10.1093\/nar\/gkh102","article-title":"The tmRNA website: reductive evolution of tmRNA in plastids and other endosymbionts","volume":"32","author":"Gueneau de Novoa P","year":"2004","unstructured":"Gueneau de NovoaPWilliamsKP. 2004. The tmRNA website: reductive evolution of tmRNA in plastids and other endosymbionts. Nucleic Acids Res. 32:D104\u2013D108.","journal-title":"Nucleic Acids Res."},{"key":"e_1_3_3_20_2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1078\/1438-4221-00149","article-title":"Role of the Hha\/YmoA family of proteins in the thermoregulation of the expression of virulence factors","volume":"291","author":"Madrid C","year":"2002","unstructured":"MadridCNietoJMJuarezA. 2002. Role of the Hha\/YmoA family of proteins in the thermoregulation of the expression of virulence factors. Int. J. Med. Microbiol. 291:425\u2013432.","journal-title":"Int. J. Med. Microbiol."},{"key":"e_1_3_3_21_2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S1369-5274(02)00299-0","article-title":"The biological roles of trans-translation","volume":"5","author":"Withey JH","year":"2002","unstructured":"WitheyJHFriedmanDI. 2002. The biological roles of trans-translation. Curr. Opin. Microbiol. 5:154\u2013159.","journal-title":"Curr. Opin. Microbiol."},{"key":"e_1_3_3_22_2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1365-2958.2012.08190.x","article-title":"ArfA recruits release factor 2 to rescue stalled ribosomes by peptidyl-tRNA hydrolysis in Escherichia coli.","volume":"86","author":"Chadani Y","year":"2012","unstructured":"ChadaniYItoKKutsukakeKAboT. 2012. ArfA recruits release factor 2 to rescue stalled ribosomes by peptidyl-tRNA hydrolysis in Escherichia coli. Mol. Microbiol. 86:37\u201350.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_23_2","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1111\/j.1365-2958.2011.07638.x","article-title":"tmRNA regulates synthesis of the ArfA ribosome rescue factor","volume":"80","author":"Garza-Sanchez F","year":"2011","unstructured":"Garza-SanchezFSchaubREJanssenBDHayesCS. 2011. tmRNA regulates synthesis of the ArfA ribosome rescue factor. Mol. Microbiol. 80:1204\u20131219.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_24_2","doi-asserted-by":"crossref","first-page":"29765","DOI":"10.1074\/jbc.M112.374074","article-title":"Proteobacterial ArfA peptides are synthesized from non-stop messenger RNAs","volume":"287","author":"Schaub RE","year":"2012","unstructured":"SchaubREPooleSJGarza-SanchezFBenbowSHayesCS. 2012. Proteobacterial ArfA peptides are synthesized from non-stop messenger RNAs. J. Biol. Chem. 287:29765\u201329775.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_3_25_2","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1111\/j.1365-2958.2011.07607.x","article-title":"Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA-and ArfA-mediated pathways","volume":"80","author":"Chadani Y","year":"2011","unstructured":"ChadaniYOnoKKutsukakeKAboT. 2011. Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA-and ArfA-mediated pathways. Mol. Microbiol. 80:772\u2013785.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_26_2","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1126\/science.1217443","article-title":"Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome","volume":"335","author":"Gagnon MG","year":"2012","unstructured":"GagnonMGSeetharamanSVBulkleyDSteitzTA. 2012. Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science 335:1370\u20131372.","journal-title":"Science"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1097"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.5.1623-1630.1994"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.6.1558-1563.2000"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0020006"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00976-09"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.120163297"},{"key":"e_1_3_3_33_2","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.vetmic.2012.04.024","article-title":"Construction of iucB and iucB-iutA mutants of avian pathogenic Escherichia coli and evaluation of their pathogenicity","volume":"159","author":"Xiong L","year":"2012","unstructured":"XiongLLingJGaoQZhouYLiTGaoSLiuX. 2012. Construction of iucB and iucB-iutA mutants of avian pathogenic Escherichia coli and evaluation of their pathogenicity. Vet. Microbiol. 159:420\u2013431.","journal-title":"Vet. Microbiol."},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.02074-12"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:BIOM.0000029432.69418.6a"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.5.1159-1165.1998"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-8-24"},{"key":"e_1_3_3_38_2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1089\/104454902753759708","article-title":"Processing of heme and heme-containing proteins by bacteria","volume":"21","author":"Stojiljkovic I","year":"2002","unstructured":"StojiljkovicIPerkins-BaldingD. 2002. Processing of heme and heme-containing proteins by bacteria. DNA Cell Biol. 21:281\u2013295.","journal-title":"DNA Cell Biol."},{"key":"e_1_3_3_39_2","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1637\/0005-2086(2002)046[0386:CRADBV]2.0.CO;2","article-title":"Complement resistance, as determined by viable count and flow cytometric methods, and its association with the presence of iss and the virulence of avian Escherichia coli.","volume":"46","author":"Nolan LK","year":"2002","unstructured":"NolanLKGiddingsCWHorneSMDoetkottCGibbsPSWooleyREFoleySL. 2002. Complement resistance, as determined by viable count and flow cytometric methods, and its association with the presence of iss and the virulence of avian Escherichia coli. Avian Dis. 46:386\u2013392.","journal-title":"Avian Dis."},{"key":"e_1_3_3_40_2","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1365-2958.2009.06632.x","article-title":"Assembly of the MreB-associated cytoskeletal ring of Escherichia coli.","volume":"72","author":"Vats P","year":"2009","unstructured":"VatsPShihYLRothfieldL. 2009. Assembly of the MreB-associated cytoskeletal ring of Escherichia coli. Mol. Microbiol. 72:170\u2013182.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_41_2","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1002\/pro.5560051219","article-title":"Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate:l-alanine ligase","volume":"5","author":"Emanuele JJ","year":"1996","unstructured":"EmanueleJJJrJinHJacobsonBLChangCYEinspahrHMVillafrancaJJ. 1996. Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate:l-alanine ligase. Protein Sci. 5:2566\u20132574.","journal-title":"Protein Sci."},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000288"},{"key":"e_1_3_3_43_2","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.jmb.2012.08.007","article-title":"ArfA recruits RF2 into stalled ribosomes","volume":"423","author":"Shimizu Y","year":"2012","unstructured":"ShimizuY. 2012. ArfA recruits RF2 into stalled ribosomes. J. Mol. Biol. 423:624\u2013631.","journal-title":"J. Mol. Biol."},{"key":"e_1_3_3_44_2","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1073\/pnas.012602299","article-title":"A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae","volume":"99","author":"Akerley BJ","year":"2002","unstructured":"AkerleyBJRubinEJNovickVLAmayaKJudsonNMekalanosJJ. 2002. A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae. Proc. Natl. Acad. Sci. U. S. A. 99:966\u2013971.","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2008.06262.x"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003810"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057537"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-143"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01236-09"},{"key":"e_1_3_3_50_2","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1365-2958.2011.07570.x","article-title":"Secretion, but not overall synthesis, of catecholate siderophores contributes to virulence of extraintestinal pathogenic Escherichia coli.","volume":"80","author":"Caza M","year":"2011","unstructured":"CazaMLepineFDozoisCM. 2011. Secretion, but not overall synthesis, of catecholate siderophores contributes to virulence of extraintestinal pathogenic Escherichia coli. Mol. Microbiol. 80:266\u2013282.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_51_2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.vetmic.2012.10.005","article-title":"Molecular prophage typing of avian pathogenic Escherichia coli.","volume":"162","author":"Kwon HJ","year":"2013","unstructured":"KwonHJSeongWJKimJH. 2013. Molecular prophage typing of avian pathogenic Escherichia coli. Vet. Microbiol. 162:785\u2013792.","journal-title":"Vet. Microbiol."},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.7.3673-3681.2003"},{"key":"e_1_3_3_53_2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.mib.2005.10.018","article-title":"Yersinia's stratagem: targeting innate and adaptive immune defense","volume":"9","author":"Heesemann J","year":"2006","unstructured":"HeesemannJSingATrulzschK. 2006. Yersinia's stratagem: targeting innate and adaptive immune defense. Curr. Opin. Microbiol. 9:55\u201361.","journal-title":"Curr. Opin. Microbiol."},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.1.536-540.2003"},{"key":"e_1_3_3_55_2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2307\/1592504","article-title":"Complement resistance-related traits among Escherichia coli isolates from apparently healthy birds and birds with colibacillosis","volume":"44","author":"Pfaff-McDonough SJ","year":"2000","unstructured":"Pfaff-McDonoughSJHorneSMGiddingsCWEbertJODoetkottCSmithMHNolanLK. 2000. Complement resistance-related traits among Escherichia coli isolates from apparently healthy birds and birds with colibacillosis. Avian Dis. 44:23\u201333.","journal-title":"Avian Dis."},{"key":"e_1_3_3_56_2","first-page":"1708","article-title":"Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA","volume":"7","author":"de la Cruz J","year":"2001","unstructured":"de la CruzJVioqueA. 2001. Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA. RNA 7:1708\u20131716.","journal-title":"RNA"},{"key":"e_1_3_3_57_2","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/75843","article-title":"The SsrA-SmpB system for protein tagging, directed degradation and ribosome rescue","volume":"7","author":"Karzai AW","year":"2000","unstructured":"KarzaiAWRocheEDSauerRT. 2000. The SsrA-SmpB system for protein tagging, directed degradation and ribosome rescue. Nat. Struct. Biol. 7:449\u2013455.","journal-title":"Nat. Struct. Biol."},{"key":"e_1_3_3_58_2","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/j.biochi.2011.05.029","article-title":"Bifunctional transfer-messenger RNA","volume":"93","author":"Keiler KC","year":"2011","unstructured":"KeilerKCRamadossNS. 2011. Bifunctional transfer-messenger RNA. Biochimie 93:1993\u20131997.","journal-title":"Biochimie"},{"key":"e_1_3_3_59_2","doi-asserted-by":"crossref","first-page":"021905","DOI":"10.1103\/PhysRevE.81.021905","article-title":"Conversion of graded to binary response in an activator-repressor system","volume":"81","author":"Karmakar R","year":"2010","unstructured":"KarmakarR. 2010. Conversion of graded to binary response in an activator-repressor system. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 81:021905.","journal-title":"Phys. Rev. E Stat. Nonlin. Soft Matter Phys."},{"key":"e_1_3_3_60_2","doi-asserted-by":"crossref","first-page":"3762","DOI":"10.1093\/emboj\/19.14.3762","article-title":"SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon","volume":"19","author":"Abo T","year":"2000","unstructured":"AboTInadaTOgawaKAibaH. 2000. SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon. EMBO J. 19:3762\u20133769.","journal-title":"EMBO J."},{"key":"e_1_3_3_61_2","doi-asserted-by":"crossref","first-page":"10220","DOI":"10.1073\/pnas.171620598","article-title":"The tRNA function of SsrA contributes to controlling repression of bacteriophage Mu prophage","volume":"98","author":"Ranquet C","year":"2001","unstructured":"RanquetCGeiselmannJToussaintA. 2001. The tRNA function of SsrA contributes to controlling repression of bacteriophage Mu prophage. Proc. Natl. Acad. Sci. U. S. A. 98:10220\u201310225.","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"e_1_3_3_62_2","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S1369-5274(00)00067-9","article-title":"Transcription termination control in bacteria","volume":"3","author":"Henkin TM","year":"2000","unstructured":"HenkinTM. 2000. Transcription termination control in bacteria. Curr. Opin. Microbiol. 3:149\u2013153.","journal-title":"Curr. Opin. Microbiol."},{"key":"e_1_3_3_63_2","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0092-8674(02)00724-9","article-title":"The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand","volume":"109","author":"Artsimovitch I","year":"2002","unstructured":"ArtsimovitchILandickR. 2002. The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand. Cell 109:193\u2013203.","journal-title":"Cell"},{"key":"e_1_3_3_64_2","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1046\/j.1365-2958.1997.6432014.x","article-title":"RfaH and the ops element, components of a novel system controlling bacterial transcription elongation","volume":"26","author":"Bailey MJ","year":"1997","unstructured":"BaileyMJHughesCKoronakisV. 1997. RfaH and the ops element, components of a novel system controlling bacterial transcription elongation. Mol. Microbiol. 26:845\u2013851.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_65_2","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1365-2958.2010.07056.x","article-title":"Functional regions of the N-terminal domain of the antiterminator RfaH","volume":"76","author":"Belogurov GA","year":"2010","unstructured":"BelogurovGASevostyanovaASvetlovVArtsimovitchI. 2010. Functional regions of the N-terminal domain of the antiterminator RfaH. Mol. Microbiol. 76:286\u2013301.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.8.4406-4413.2002"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028413"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004809"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004459"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01838-06"},{"key":"e_1_3_3_71_2","first-page":"164","article-title":"The isolation and identification of pathogenic Escherichia coli isolates of chicken origin from some regions in China","volume":"30","author":"Gao S","year":"1999","unstructured":"GaoSLiuXZhangRZhangRJiaoXWenQWuCTangYZhuXLiCChenJCuiH. 1999. The isolation and identification of pathogenic Escherichia coli isolates of chicken origin from some regions in China. Acta Vet. Zootechnol. Sin. 30:164\u2013171.","journal-title":"Acta Vet. Zootechnol. Sin."}],"container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.00628-13","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.00628-13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T17:33:47Z","timestamp":1627580027000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JB.00628-13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,15]]},"references-count":70,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2013,11,15]]}},"alternative-id":["10.1128\/JB.00628-13"],"URL":"https:\/\/doi.org\/10.1128\/jb.00628-13","relation":{},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"value":"0021-9193","type":"print"},{"value":"1098-5530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,15]]},"assertion":[{"value":"2013-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-08-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}