{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:14:38Z","timestamp":1773659678112,"version":"3.50.1"},"reference-count":47,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Walter Ehrstr\u00f6m Foundation"},{"name":"MBDP doctoral program University of Helsinki"},{"DOI":"10.13039\/100007797","name":"Helsingin Yliopisto","doi-asserted-by":"publisher","award":["313\/51\/2013"],"award-info":[{"award-number":["313\/51\/2013"]}],"id":[{"id":"10.13039\/100007797","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2019,4,15]]},"abstract":"<jats:p>\n                    Despite the fact that\n                    <jats:named-content content-type=\"genus-species\">Campylobacter coli<\/jats:named-content>\n                    a major foodborne pathogen, its glycobiology has been largely neglected. The genetic makeup of the\n                    <jats:named-content content-type=\"genus-species\">C. coli<\/jats:named-content>\n                    lipooligosaccharide biosynthesis locus was largely unknown until recently.\n                    <jats:named-content content-type=\"genus-species\">C. coli<\/jats:named-content>\n                    harbors a large set of genes associated with lipooligosaccharide biosynthesis, including genes for several putative glycosyltransferases involved in the synthesis of sialylated lipooligosaccharide in\n                    <jats:named-content content-type=\"genus-species\">Campylobacter jejuni<\/jats:named-content>\n                    . In the present study,\n                    <jats:named-content content-type=\"genus-species\">C. coli<\/jats:named-content>\n                    was found to express lipooligosaccharide structures containing sialic acid and other nonulosonate acids. These findings have a strong impact on our understanding of\n                    <jats:named-content content-type=\"genus-species\">C. coli<\/jats:named-content>\n                    ecology, host-pathogen interaction, and pathogenesis.\n                  <\/jats:p>","DOI":"10.1128\/jb.00759-18","type":"journal-article","created":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T06:54:14Z","timestamp":1548658454000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Genetics behind the Biosynthesis of Nonulosonic Acid-Containing Lipooligosaccharides in Campylobacter coli"],"prefix":"10.1128","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9716-8154","authenticated-orcid":false,"given":"Alejandra","family":"Kolehmainen","sequence":"first","affiliation":[{"name":"Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1585-6384","authenticated-orcid":false,"given":"Mirko","family":"Rossi","sequence":"additional","affiliation":[{"name":"Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland"},{"name":"European Food Safety Authority, Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Stupak","sequence":"additional","affiliation":[{"name":"Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjun","family":"Li","sequence":"additional","affiliation":[{"name":"Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0204-4408","authenticated-orcid":false,"given":"Michel","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1539-1679","authenticated-orcid":false,"given":"Warren","family":"Wakarchuk","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biology, Ryerson University, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr000407m"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.2000.01335.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01509.x"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.12.5939-5947.1998"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70132-X"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00321-08"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1178"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00254-08"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M108452200"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2012.12.010"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00872-06"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200415707"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.181750"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2005.09.004"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.6.3896"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/170.4.828"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2006.02.010"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(99)00106-6"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-008-0661-9"},{"key":"e_1_3_3_21_2","doi-asserted-by":"crossref","unstructured":"Culebro A Machado MP Carri\u00e7o JA Rossi M. 2017. Origin evolution and distribution of the molecular machinery for biosynthesis of sialylated lipooligosaccharide structures in Campylobacter coli . bioRxiv doi:10.1101\/225771.","DOI":"10.1101\/225771"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-15-129"},{"key":"e_1_3_3_23_2","doi-asserted-by":"crossref","unstructured":"Kolehmainen A Rossi M Stupak J Li J Gilbert M Wakarchuk W. 2018. Genetics behind the biosynthesis of nonulosonic acid containing lipooligosaccharides in Campylobacter coli . bioRxiv https:\/\/doi.org\/10.1101\/254235.","DOI":"10.1101\/254235"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi602543d"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb720"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.12.6656-6662.2000"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2009.07.004"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0903014"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1301536"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034416"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00347-16"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cws071"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi901606n"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.261172"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth899"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwl010"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwp039"},{"key":"e_1_3_3_38_2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1042\/BJ20040218","article-title":"Characterization of N-acetylneuraminic acid synthase isoenzyme 1 from Campylobacter jejuni","volume":"383","author":"Sundaram A","year":"2004","unstructured":"Sundaram A, Pitts L, Muhammad K, Wu J, Betenbaugh M, Woodard R, Vann W. 2004. Characterization of N-acetylneuraminic acid synthase isoenzyme 1 from Campylobacter jejuni. Biochem J 383:83\u201389. http:\/\/www.biochemj.org\/content\/383\/1\/83.abstract.","journal-title":"Biochem J"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01780.x"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0902431106"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M611027200"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.03185.x"},{"key":"e_1_3_3_43_2","first-page":"179","volume-title":"Essentials of glycobiology","author":"Varki A","year":"2017","unstructured":"Varki A, Schnaar RL, Schauer R. 2017. Sialic acids and other nonulosonic acids, p 179\u2013195. In Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH (ed), Essentials of glycobiology, 3rd ed. The Consortium of Glycobiology Editors, La Jolla, CA.","edition":"3"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2010.02307.x"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000304"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01023-12"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200500145"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwm090"}],"container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.00759-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.00759-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T13:48:29Z","timestamp":1627566509000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JB.00759-18"}},"subtitle":[],"editor":[{"given":"Thomas J.","family":"Silhavy","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,4,15]]},"references-count":47,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,4,15]]}},"alternative-id":["10.1128\/JB.00759-18"],"URL":"https:\/\/doi.org\/10.1128\/jb.00759-18","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/254235","asserted-by":"object"}]},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"value":"0021-9193","type":"print"},{"value":"1098-5530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,15]]},"assertion":[{"value":"2018-12-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}