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This obligate intracellular bacterium produces infectious progeny within an infected human cell through the expression of late chlamydial genes. We showed that the ability of a key chlamydial transcription factor, EUO, to repress late genes was enhanced by a plasmid-encoded protein, Pgp4. In addition, studies with\n            <jats:italic>Chlamydia<\/jats:italic>\n            Pgp4-deficient strains provide evidence that Pgp4 delays late gene expression in infected cells. Thus, Pgp4 is a novel regulator of late gene expression in\n            <jats:italic>Chlamydia<\/jats:italic>\n            through its ability to enhance the repressor function of EUO.\n          <\/jats:p>","DOI":"10.1128\/jb.00793-19","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T10:23:15Z","timestamp":1580120595000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["The Repressor Function of the\n            <i>Chlamydia<\/i>\n            Late Regulator EUO Is Enhanced by the Plasmid-Encoded Protein Pgp4"],"prefix":"10.1128","volume":"202","author":[{"given":"Qiang","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, China Agricultural University, Beijing, China"},{"name":"Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Rosario","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren M.","family":"Sheehan","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed M.","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Brothwell","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"He","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5361-583X","authenticated-orcid":false,"given":"Ming","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA"},{"name":"Department of Medicine, University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02432-0"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/mr.55.1.143-190.1991"},{"key":"e_1_3_3_4_2","first-page":"2301","volume-title":"Mandell, Douglas, and Bennett\u2019s principles and practice of infectious diseases","author":"Batteiger BE","year":"2019","unstructured":"Batteiger BE, Tan M. 2019. 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