{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:07:28Z","timestamp":1766066848422},"reference-count":48,"publisher":"American Society for Microbiology","issue":"16","license":[{"start":{"date-parts":[[2018,8,15]],"date-time":"2018-08-15T00:00:00Z","timestamp":1534291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2018,8,15]]},"abstract":"<jats:p>\n            Bacterial meningitis is a serious global health problem, and one of the major causative organisms is\n            <jats:named-content content-type=\"genus-species\">Neisseria meningitidis<\/jats:named-content>\n            , which is also a common commensal in the upper respiratory tract of healthy humans. In bacteria, numerous loci involved in biosynthesis of surface-exposed antigenic structures that are involved in the interaction between bacteria and host are frequently subjected to homologous recombination and phase variation. These mechanisms are well described in\n            <jats:named-content content-type=\"genus-species\">Neisseria<\/jats:named-content>\n            , and phase variation provides the ability to change these structures reversibly in response to the environment. Protein glycosylation systems are becoming widely identified in bacteria, and yet little is known about the mechanisms and evolutionary forces influencing glycan composition during carriage and disease.\n          <\/jats:p>","DOI":"10.1128\/jb.00794-17","type":"journal-article","created":{"date-parts":[[2018,3,20]],"date-time":"2018-03-20T12:48:27Z","timestamp":1521550107000},"update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Genotypic and Phenotypic Characterization of the\n            <i>O<\/i>\n            -Linked Protein Glycosylation System Reveals High Glycan Diversity in Paired Meningococcal Carriage Isolates"],"prefix":"10.1128","volume":"200","author":[{"given":"Bente","family":"B\u00f8rud","sequence":"first","affiliation":[{"name":"Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guro K.","family":"B\u00e5rnes","sequence":"additional","affiliation":[{"name":"Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway"},{"name":"Faculty of Medicine, University of Oslo, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ola Br\u00f8nstad","family":"Brynildsrud","sequence":"additional","affiliation":[{"name":"Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Fritzs\u00f8nn","sequence":"additional","affiliation":[{"name":"Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique A.","family":"Caugant","sequence":"additional","affiliation":[{"name":"Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway"},{"name":"Faculty of Medicine, University of Oslo, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70288-8"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105033441807"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61016-2"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1996.tb02641.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/374740"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-148-6-1813"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/427875"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2015.1010228"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.7.2898-2901.2004"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/512084"},{"key":"e_1_3_3_12_2","first-page":"759","article-title":"Regulation of capsule in Neisseria meningitidis","volume":"42","author":"Tzeng YL","year":"2016","unstructured":"Tzeng YL, Thomas J, Stephens DS. 2016. 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