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Here, we show that<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Y. pestis<\/jats:named-content>infects and replicates as a biofilm in the foregut of cat fleas in a manner requiring<jats:italic>hmsFR<\/jats:italic>, two determinants for extracellular biofilm matrix. Examining a library of transposon insertion mutants, we identified the LysR-type transcriptional regulator YfbA, which is essential for<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Y. pestis<\/jats:named-content>colonization and biofilm formation in cat fleas.<\/jats:p>","DOI":"10.1128\/jb.01187-13","type":"journal-article","created":{"date-parts":[[2014,1,4]],"date-time":"2014-01-04T03:13:10Z","timestamp":1388805190000},"page":"1165-1173","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":22,"title":["YfbA, a Yersinia pestis Regulator Required for Colonization and Biofilm Formation in the Gut of Cat Fleas"],"prefix":"10.1128","volume":"196","author":[{"given":"Christina","family":"Tam","sequence":"first","affiliation":[{"name":"Howard Taylor Ricketts Laboratory, Argonne National Laboratory, Lemont, Illinois, USA; Department of Microbiology, University of Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen","family":"Demke","sequence":"additional","affiliation":[{"name":"Howard Taylor Ricketts Laboratory, Argonne National Laboratory, Lemont, Illinois, USA; Department of Microbiology, University of Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Hermanas","sequence":"additional","affiliation":[{"name":"Howard Taylor Ricketts Laboratory, Argonne National Laboratory, Lemont, Illinois, USA; Department of Microbiology, University of Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Howard Taylor Ricketts Laboratory, Argonne National Laboratory, Lemont, Illinois, USA; Department of Microbiology, University of Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni P. 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