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In this work, we investigated the role of the\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">mar-sox-rob<\/jats:named-content>\n            regulon in regulating outer membrane porin expression in response to salicylate. We provide both genetic and physiological evidence that MarA and Rob can independently activate\n            <jats:italic>micF<\/jats:italic>\n            transcription in response to salicylate, leading to reduced OmpF expression. MarA was also found to repress OmpF expression through a MicF-independent pathway. In the case of OmpC, we found that its transcription was moderately increased in response to salicylate. However, this increase was independent of MarA and Rob. Finally, we found that the reduction in OmpF expression in a\n            <jats:italic>tolC<\/jats:italic>\n            mutant is due primarily to Rob. Collectively, this work further clarifies the coordinated role of MarA and Rob in regulating the expression of the outer membrane porins.\n          <\/jats:p>","DOI":"10.1128\/jb.01382-10","type":"journal-article","created":{"date-parts":[[2011,3,14]],"date-time":"2011-03-14T00:08:17Z","timestamp":1300061297000},"page":"2252-2260","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":53,"title":["Role of the mar-sox-rob Regulon in Regulating Outer Membrane Porin Expression"],"prefix":"10.1128","volume":"193","author":[{"given":"Lon M.","family":"Chubiz","sequence":"first","affiliation":[{"name":"Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher V.","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)84666-5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.jmb.2006.08.002","article-title":"Crystal structure of osmoporin OmpC from E. coli at 2.0 A","volume":"362","author":"Basle A.","year":"2006","unstructured":"BasleA. 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