{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:06:30Z","timestamp":1791295590474,"version":"4.1.0"},"reference-count":62,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The\n            <jats:italic>yjjQ<\/jats:italic>\n            and\n            <jats:italic>bglJ<\/jats:italic>\n            genes encode LuxR-type transcription factors conserved in several enterobacterial species. YjjQ is a potential virulence factor in avian pathogenic\n            <jats:italic>Escherichia coli<\/jats:italic>\n            . BglJ counteracts the silencing of the\n            <jats:italic>bgl<\/jats:italic>\n            (\u03b2-glucoside) operon by H-NS in\n            <jats:italic>E. coli<\/jats:italic>\n            K-12. Here we show that\n            <jats:italic>yjjQ<\/jats:italic>\n            and\n            <jats:italic>bglJ<\/jats:italic>\n            form an operon carried by\n            <jats:italic>E. coli<\/jats:italic>\n            K-12, whose expression is repressed by the histone-like nucleoid structuring (H-NS) protein. The LysR-type transcription factor LeuO counteracts this repression. Furthermore, the\n            <jats:italic>yjjP<\/jats:italic>\n            gene, encoding a membrane protein of unknown function and located upstream in divergent orientation to the\n            <jats:italic>yjjQ<\/jats:italic>\n            -\n            <jats:italic>bglJ<\/jats:italic>\n            operon, is likewise repressed by H-NS. Mapping of the promoters as well as the H-NS and LeuO binding sites within the 555-bp intergenic region revealed that H-NS binds to the center of the AT-rich regulatory region and distal to the divergent promoters. LeuO sites map to the center and to positions distal to the\n            <jats:italic>yjjQ<\/jats:italic>\n            promoters, while one LeuO binding site overlaps with the divergent\n            <jats:italic>yjjP<\/jats:italic>\n            promoter. This latter LeuO site is required for full derepression of the\n            <jats:italic>yjjQ<\/jats:italic>\n            promoters. The arrangement of regulatory sites suggests that LeuO restructures the nucleoprotein complex formed by H-NS. Furthermore, the data support the conclusion that LeuO, whose expression is likewise repressed by H-NS and which is a virulence factor in\n            <jats:italic>Salmonella enterica<\/jats:italic>\n            , is a master regulator that among other loci, also controls the\n            <jats:italic>yjjQ-bglJ<\/jats:italic>\n            operon and thus indirectly the presumptive targets of YjjQ and BglJ.\n          <\/jats:p>","DOI":"10.1128\/jb.01447-07","type":"journal-article","created":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T01:46:05Z","timestamp":1196473565000},"page":"926-935","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":48,"title":["Regulation of the\n            <i>yjjQ<\/i>\n            -\n            <i>bglJ<\/i>\n            Operon, Encoding LuxR-Type Transcription Factors, and the Divergent\n            <i>yjjP<\/i>\n            Gene by H-NS and LeuO"],"prefix":"10.1128","volume":"190","author":[{"given":"Thomas","family":"Stratmann","sequence":"first","affiliation":[{"name":"Institut fu\u0308r Genetik, Universita\u0308t zu Ko\u0308ln, Zu\u0308lpicher Str. 47, 50674 Ko\u0308ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Madhusudan","sequence":"additional","affiliation":[{"name":"Institut fu\u0308r Genetik, Universita\u0308t zu Ko\u0308ln, Zu\u0308lpicher Str. 47, 50674 Ko\u0308ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Schnetz","sequence":"additional","affiliation":[{"name":"Institut fu\u0308r Genetik, Universita\u0308t zu Ko\u0308ln, Zu\u0308lpicher Str. 47, 50674 Ko\u0308ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"Current protocols in molecular biology. 2005"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"41657","DOI":"10.1074\/jbc.M206037200","volume":"277","year":"2002","unstructured":"Badaut, C., R. Williams, V. Arluison, E. Bouffartigues, B. Robert, H. Buc, and S. Rimsky. 2002. The degree of oligomerization of the H-NS nucleoid structuring protein is related to specific binding to DNA. J. Biol. Chem. 277 : 41657-41666.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/nsmb1233","volume":"14","year":"2007","unstructured":"Bouffartigues, E., M. Buckle, C. Badaut, A. Travers, and S. Rimsky. 2007. H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing. Nat. Struct. Mol. Biol. 14 : 441-448.","journal-title":"Nat. Struct. Mol. Biol."},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"5101","DOI":"10.1074\/jbc.M411840200","volume":"280","year":"2005","unstructured":"Chen, C. C., M. Y. Chou, C. H. Huang, A. Majumder, and H. Y. Wu. 2005. A cis-spreading nucleoprotein filament is responsible for the gene silencing activity found in the promoter relay mechanism. J. Biol. Chem. 280 : 5101-5112.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"9478","DOI":"10.1074\/jbc.M010501200","volume":"276","year":"2001","unstructured":"Chen, C. C., M. Fang, A. Majumder, and H. Y. Wu. 2001. A 72-base pair AT-rich DNA sequence element functions as a bacterial gene silencer. J. Biol. Chem. 276 : 9478-9485.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"38094","DOI":"10.1074\/jbc.M300461200","volume":"278","year":"2003","unstructured":"Chen, C. C., M. Ghole, A. Majumder, Z. Wang, S. Chandana, and H. Y. Wu. 2003. LeuO-mediated transcriptional derepression. J. Biol. Chem. 278 : 38094-38103.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","first-page":"15111","DOI":"10.1074\/jbc.M414544200","volume":"280","year":"2005","unstructured":"Chen, C. C., and H. Y. Wu. 2005. LeuO protein delimits the transcriptionally active and repressive domains on the bacterial chromosome. J. Biol. Chem. 280 : 15111-15121.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1126\/science.1109730","volume":"308","year":"2005","unstructured":"Daley, D. O., M. Rapp, E. Granseth, K. Melen, D. Drew, and G. von Heijne. 2005. Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 : 1321-1323.","journal-title":"Science"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1074\/jbc.C100603200","volume":"277","year":"2002","unstructured":"Dame, R. T., C. Wyman, R. Wurm, R. Wagner, and N. Goosen. 2002. Structural basis for H-NS-mediated trapping of RNA polymerase in the open initiation complex at the rrnB P1. J. Biol. Chem. 277 : 2146-2150.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/nature05283","volume":"444","year":"2006","unstructured":"Dame, R. T., M. C. Noom, and G. J. L. Wuite. 2006. Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation. Nature 444 : 387-390.","journal-title":"Nature"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.120163297"},{"key":"e_1_3_2_13_2","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1365-2958.2007.05958.x","volume":"66","year":"2007","unstructured":"De la Cruz, M. A., M. Fernandez-Mora, C. Guadarrama, M. A. Flores-Valdez, V. H. Bustamante, A. Vazquez, and E. Calva. 2007. LeuO antagonizes H-NS and StpA-dependent repression in Salmonella enterica ompS1. Mol. Microbiol. 66 : 727-743.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/0147-619X(92)90032-6","volume":"28","year":"1992","unstructured":"Diederich, L., L. J. Rasmussen, and W. Messer. 1992. New cloning vectors for integration into the lambda attachment site attB of the Escherichia coli chromosome. Plasmid 28 : 14-24.","journal-title":"Plasmid"},{"key":"e_1_3_2_15_2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1046\/j.1365-2958.2002.02734.x","volume":"43","year":"2002","unstructured":"Dole, S., S. K\u00fchn, and K. Schnetz. 2002. Post-transcriptional enhancement of Escherichia coli bgl operon silencing by limitation of BglG-mediated antitermination at low transcription rates. Mol. Microbiol. 43 : 217-226.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_16_2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1365-2958.2004.04001.x","volume":"52","year":"2004","unstructured":"Dole, S., V. Nagarajavel, and K. Schnetz. 2004. The histone-like nucleoid structuring protein H-NS represses the Escherichia coli bgl operon downstream of the promoter. Mol. Microbiol. 52 : 589-600.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nrmicro883","volume":"2","year":"2004","unstructured":"Dorman, C. J. 2004. H-NS: a universal regulator for a dynamic genome. Nat. Rev. Microbiol. 2 : 391-400.","journal-title":"Nat. Rev. Microbiol."},{"key":"e_1_3_2_18_2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/bies.20542","volume":"29","year":"2007","unstructured":"Dorman, C. J. 2007. Probing bacterial nucleoid structure with optical tweezers. BioEssays 29 : 212-216.","journal-title":"BioEssays"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/nrmicro1598","volume":"5","year":"2007","unstructured":"Dorman, C. J. 2007. H-NS, the genome sentinel. Nat. Rev. Microbiol. 5 : 157-161.","journal-title":"Nat. Rev. Microbiol."},{"key":"e_1_3_2_20_2","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.jmb.2006.09.090","volume":"367","year":"2007","unstructured":"Ezezika, O. C., S. Haddad, T. J. Clark, E. L. Neidle, and C. Momany. 2007. Distinct effector-binding sites enable synergistic transcriptional activation by BenM, a LysR-type regulator. J. Mol. Biol. 367 : 616-629.","journal-title":"J. Mol. Biol."},{"key":"e_1_3_2_21_2","doi-asserted-by":"crossref","first-page":"29929","DOI":"10.1074\/jbc.273.45.29929","volume":"273","year":"1998","unstructured":"Fang, M., and H. Y. Wu. 1998. Suppression of leu-500 mutation in topA + Salmonella typhimurium strains. The promoter relay at work. J. Biol. Chem. 273 : 29929-29934.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.3.626-633.1998"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.10.2909-2920.2004"},{"key":"e_1_3_2_24_2","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/genetics\/143.2.627","volume":"143","year":"1996","unstructured":"Giel, M., M. Desnoyer, and J. Lopilato. 1996. A mutation in a new gene, bglJ, activates the bgl operon in Escherichia coli K-12. Genetics 143 : 627-635.","journal-title":"Genetics"},{"key":"e_1_3_2_25_2","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1093\/nar\/gkl542","volume":"34","year":"2006","unstructured":"Grainger, D. C., D. Hurd, M. D. Goldberg, and S. J. Busby. 2006. Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome. Nucleic Acids Res. 34 : 4642-4652.","journal-title":"Nucleic Acids Res."},{"key":"e_1_3_2_26_2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1046\/j.1365-2958.2001.02358.x","volume":"40","year":"2001","unstructured":"Hommais, F., E. Krin, C. Laurent-Winter, O. Soutourina, A. Malpertuy, J. P. Le Caer, A. Danchin, and P. Bertin. 2001. Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS. Mol. Microbiol. 40 : 20-36.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_27_2","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1046\/j.1365-2958.1997.4911852.x","volume":"25","year":"1997","unstructured":"Klauck, E., J. Bohringer, and R. Hengge-Aronis. 1997. The LysR-like regulator LeuO in Escherichia coli is involved in the translational regulation of rpoS by affecting the expression of the small regulatory DsrA-RNA. Mol. Microbiol. 25 : 559-569.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_28_2","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1101\/gad.1520507","volume":"21","year":"2007","unstructured":"Laishram, R. S., and J. Gowrishankar. 2007. Environmental regulation operating at the promoter clearance step of bacterial transcription. Genes Dev. 21 : 1258-1272.","journal-title":"Genes Dev."},{"key":"e_1_3_2_29_2","doi-asserted-by":"crossref","first-page":"6330","DOI":"10.1093\/nar\/gkm712","volume":"35","year":"2007","unstructured":"Lang, B., N. Blot, E. Bouffartigues, M. Buckle, M. Geertz, C. O. Gualerzi, R. Mavathur, G. Muskhelishvili, C. L. Pon, S. Rimsky, S. Stella, M. M. Babu, and A. Travers. 2007. High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes. Nucleic Acids Res. 35 : 6330-6337.","journal-title":"Nucleic Acids Res."},{"key":"e_1_3_2_30_2","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1371\/journal.ppat.0020011","volume":"2","year":"2006","unstructured":"Lawley, T. D., K. Chan, L. J. Thompson, C. C. Kim, G. R. Govoni, and D. M. Monack. 2006. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS Pathog. 2 : e11.","journal-title":"PLoS Pathog."},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00528-07"},{"key":"e_1_3_2_32_2","doi-asserted-by":"crossref","first-page":"12456","DOI":"10.1073\/pnas.95.21.12456","volume":"95","year":"1998","unstructured":"Lease, R. A., M. E. Cusick, and M. Belfort. 1998. Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci. Proc. Natl. Acad. Sci. USA 95 : 12456-12461.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"e_1_3_2_33_2","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.jmb.2004.10.006","volume":"344","year":"2004","unstructured":"Lease, R. A., and S. A. Woodson. 2004. Cycling of the Sm-like protein Hfq on the DsrA small regulatory RNA. J. Mol. Biol. 344 : 1211-1223.","journal-title":"J. Mol. Biol."},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.5.2818-2827.2005"},{"key":"e_1_3_2_35_2","doi-asserted-by":"crossref","first-page":"7024","DOI":"10.1073\/pnas.84.20.7024","volume":"84","year":"1987","unstructured":"Liu, L. F., and J. C. Wang. 1987. Supercoiling of the DNA template during transcription. Proc. Natl. Acad. Sci. USA 84 : 7024-7027.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"e_1_3_2_36_2","doi-asserted-by":"crossref","first-page":"16476","DOI":"10.1074\/jbc.M610838200","volume":"282","year":"2007","unstructured":"Lorca, G. L., A. Ezersky, V. V. Lunin, J. R. Walker, S. Altamentova, E. Evdokimova, M. Vedadi, A. Bochkarev, and A. Savchenko. 2007. Glyoxylate and pyruvate are antagonistic effectors of the Escherichia coli IclR transcriptional regulator. J. Biol. Chem. 282 : 16476-16491.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_37_2","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1371\/journal.ppat.0020081","volume":"2","year":"2006","unstructured":"Lucchini, S., G. Rowley, M. D. Goldberg, D. Hurd, M. Harrison, and J. C. D. Hinton. 2006. H-NS mediates the silencing of laterally acquired genes in bacteria. PLoS Pathog. 2 : e81.","journal-title":"PLoS Pathog."},{"key":"e_1_3_2_38_2","doi-asserted-by":"crossref","first-page":"6578","DOI":"10.1016\/S0021-9258(17)37411-2","volume":"269","year":"1994","unstructured":"Lucht, J. M., P. Dersch, B. Kempf, and E. Bremer. 1994. Interactions of the nucleoid-associated DNA-binding protein H-NS with the regulatory region of the osmotically controlled proU operon of Escherichia coli. J. Biol. Chem. 269 : 6578-6586.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_39_2","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jsb.2006.05.006","volume":"156","year":"2006","unstructured":"Luijsterburg, M. S., M. C. Noom, G. J. Wuite, and R. T. Dame. 2006. The architectural role of nucleoid-associated proteins in the organization of bacterial chromatin: a molecular perspective. J. Struct. Biol. 156 : 262-272.","journal-title":"J. Struct. Biol."},{"key":"e_1_3_2_40_2","doi-asserted-by":"crossref","first-page":"3349","DOI":"10.1099\/mic.0.28080-0","volume":"151","year":"2005","unstructured":"Madhusudan, S., A. Paukner, Y. Klingen, and K. Schnetz. 2005. Independent regulation of H-NS mediated silencing of the bgl operon at two levels: upstream by BglJ and LeuO and downstream by DnaKJ. Microbiology 151 : 3349-3359.","journal-title":"Microbiology"},{"key":"e_1_3_2_41_2","unstructured":"Experiments in molecular genetics. 1972"},{"key":"e_1_3_2_42_2","unstructured":"A short course in bacterial genetics. 1992"},{"key":"e_1_3_2_43_2","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1111\/j.1365-2958.2005.04797.x","volume":"57","year":"2005","unstructured":"Moorthy, S., and P. I. Watnick. 2005. Identification of novel stage-specific genetic requirements through whole genome transcription profiling of Vibrio cholerae biofilm development. Mol. Microbiol. 57 : 1623-1635.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_44_2","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0968-0004(98)01265-1","volume":"23","year":"1998","unstructured":"Munteanu, M. G., K. Vlahovicek, S. Parthasarathy, I. Simon, and S. Pongor. 1998. Rod models of DNA: sequence-dependent anisotropic elastic modelling of local bending phenomena. Trends Biochem. Sci. 23 : 341-347.","journal-title":"Trends Biochem. Sci."},{"key":"e_1_3_2_45_2","doi-asserted-by":"crossref","first-page":"23622","DOI":"10.1074\/jbc.M702753200","volume":"282","year":"2007","unstructured":"Nagarajavel, V., S. Madhusudan, S. Dole, A. R. Rahmouni, and K. Schnetz. 2007. Repression by binding of H-NS within the transcription unit. J. Biol. Chem. 282 : 23622-23630.","journal-title":"J. Biol. Chem."},{"key":"e_1_3_2_46_2","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1101\/gad.1543107","volume":"21","year":"2007","unstructured":"Navarre, W. W., M. McClelland, S. J. Libby, and F. C. Fang. 2007. Silencing of xenogeneic DNA by H-NS-facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA. Genes Dev. 21 : 1456-1471.","journal-title":"Genes Dev."},{"key":"e_1_3_2_47_2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1126\/science.1128794","volume":"313","year":"2006","unstructured":"Navarre, W. W., S. Porwollik, Y. Wang, M. McClelland, H. Rosen, S. J. Libby, and F. C. Fang. 2006. Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella. Science 313 : 236-238.","journal-title":"Science"},{"key":"e_1_3_2_48_2","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1111\/j.1365-2958.2001.02309.x","volume":"39","year":"2001","unstructured":"Opel, M. L., S. M. Arfin, and G. W. Hatfield. 2001. The effects of DNA supercoiling on the expression of operons of the ilv regulon of Escherichia coli suggest a physiological rationale for divergently transcribed operons. Mol. Microbiol. 39 : 1109-1115.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_49_2","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/dnares\/dsl009","volume":"13","year":"2006","unstructured":"Oshima, T., S. Ishikawa, K. Kurokawa, H. Aiba, and N. Ogasawara. 2006. Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA Polymerase. DNA Res. 13 : 141-153.","journal-title":"DNA Res."},{"key":"e_1_3_2_50_2","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1046\/j.1365-2958.2003.03848.x","volume":"51","year":"2004","unstructured":"Prosseda, G., M. Falconi, M. Giangrossi, C. O. Gualerzi, G. Micheli, and B. Colonna. 2004. The virF promoter in Shigella: more than just a curved DNA stretch. Mol. Microbiol. 51 : 523-537.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.13.4012-4023.2001"},{"key":"e_1_3_2_52_2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.mib.2004.02.001","volume":"7","year":"2004","unstructured":"Rimsky, S. 2004. Structure of the histone-like protein H-NS and its role in regulation and genome superstructure. Curr. Opin. Microbiol. 7 : 109-114.","journal-title":"Curr. Opin. Microbiol."},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.2.1398-1402.2006"},{"key":"e_1_3_2_54_2","unstructured":"Molecular cloning: a laboratory manual. 2001"},{"key":"e_1_3_2_55_2","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1146\/annurev.mi.47.100193.003121","volume":"47","year":"1993","unstructured":"Schell, M. A. 1993. Molecular biology of the LysR family of transcriptional regulators. Annu. Rev. Microbiol. 47 : 597-626.","journal-title":"Annu. Rev. Microbiol."},{"key":"e_1_3_2_56_2","first-page":"945","volume":"383","year":"2002","unstructured":"Schr\u00f6der, O., and R. Wagner. 2002. The bacterial regulatory protein H-NS\u2014a versatile modulator of nucleic acid structures. Biol. Chem. 383 : 945-960.","journal-title":"Biol. Chem."},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.3.810-814.1995"},{"key":"e_1_3_2_58_2","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1101\/gad.1316305","volume":"19","year":"2005","unstructured":"Shin, M., M. Song, J. H. Rhee, Y. Hong, Y. J. Kim, Y. J. Seok, K. S. Ha, S. H. Jung, and H. E. Choy. 2005. DNA looping-mediated repression by histone-like protein H-NS: specific requirement of E\u03c370 as a cofactor for looping. Genes Dev. 19 : 2388-2398.","journal-title":"Genes Dev."},{"key":"e_1_3_2_59_2","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.cub.2004.05.050","volume":"14","year":"2004","unstructured":"Tenor, J. L., B. A. McCormick, F. M. Ausubel, and A. Aballay. 2004. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Curr. Biol. 14 : 1018-1024.","journal-title":"Curr. Biol."},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01813-06"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.1.190-193.1998"},{"key":"e_1_3_2_62_2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/280080a0","volume":"280","year":"1979","unstructured":"Wilson, G. G., K. Y. K. Young, G. J. Edlin, and W. Konigsberg. 1979. High-frequency generalised transduction by bacteriophage T4. Nature 280 : 80-82.","journal-title":"Nature"},{"key":"e_1_3_2_63_2","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0092-8674(95)90433-6","volume":"82","year":"1995","unstructured":"Wu, H.-Y., J. Tan, and M. Fang. 1995. Long-range interaction between two promoters: activation of the leu-500 promoter by a distant upstream promoter. Cell 82 : 445-451.","journal-title":"Cell"}],"container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.01447-07","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JB.01447-07","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T17:43:35Z","timestamp":1627580615000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JB.01447-07"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":62,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["10.1128\/JB.01447-07"],"URL":"https:\/\/doi.org\/10.1128\/jb.01447-07","relation":{},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"value":"0021-9193","type":"print"},{"value":"1098-5530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2]]},"assertion":[{"value":"2007-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-11-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}