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These zoonotic infections result in significant amounts of\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">C. jejuni<\/jats:named-content>\n            present in the food supply to contribute to disease in humans. We previously found that a transposon insertion in\n            <jats:italic>Cjj81176_1038<\/jats:italic>\n            , encoding a homolog of the\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Escherichia coli<\/jats:named-content>\n            LivJ periplasmic binding protein of the leucine, isoleucine, and valine (LIV) branched-chain amino acid transport system, reduced the commensal colonization capacity of\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">C. jejuni<\/jats:named-content>\n            81-176 in chicks.\n            <jats:italic>Cjj81176_1038<\/jats:italic>\n            is the first gene of a six-gene locus that encodes homologous components of the\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">E. coli<\/jats:named-content>\n            LIV system. By analyzing mutants with in-frame deletions of individual genes or pairs of genes, we found that this system constitutes a LIV transport system in\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">C. jejuni<\/jats:named-content>\n            responsible for a high level of leucine acquisition and, to a lesser extent, isoleucine and valine acquisition. Despite each LIV protein being required for branched-chain amino acid transport, only the LivJ and LivK periplasmic binding proteins were required for wild-type levels of commensal colonization of chicks. All LIV permease and ATPase components were dispensable for\n            <jats:italic>in vivo<\/jats:italic>\n            growth. These results suggest that the biological functions of LivJ and LivK for colonization are more complex than previously hypothesized and extend beyond a role for binding and acquiring branched-chain amino acids during commensalism. In contrast to other studies indicating a requirement and utilization of other specific amino acids for colonization, acquisition of branched-chain amino acids does not appear to be a determinant for\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">C. jejuni<\/jats:named-content>\n            during commensalism.\n          <\/jats:p>","DOI":"10.1128\/jb.05473-11","type":"journal-article","created":{"date-parts":[[2011,9,24]],"date-time":"2011-09-24T06:08:52Z","timestamp":1316844532000},"page":"6233-6243","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":30,"title":["Analysis of the LIV System of Campylobacter jejuni Reveals Alternative Roles for LivJ and LivK in Commensalism beyond Branched-Chain Amino Acid Transport"],"prefix":"10.1128","volume":"193","author":[{"given":"Deborah A.","family":"Ribardo","sequence":"first","affiliation":[{"name":"Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9048"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Hendrixson","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9048"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)38417-0"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.130.1.384-392.1977"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.126.1.80-90.1976"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.54.10.2365-2370.1988"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01430-07"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1093\/infdis\/157.3.472","article-title":"Experimental Campylobacter jejuni infection in humans","volume":"157","author":"Black R. 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