{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T10:34:58Z","timestamp":1774780498488,"version":"3.50.1"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[1973,7,1]],"date-time":"1973-07-01T00:00:00Z","timestamp":110332800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[1973,7]]},"abstract":"<jats:p>\n            <jats:italic>Saccharomyces cerevisiae<\/jats:italic>\n            was grown in batch culture over a wide range of oxygen concentrations, varying from the anaerobic condition to a maximal dissolved oxygen concentration of 3.5 \u03bcM. The development of cells was assayed by measuring amounts of the aerobic cytochromes\n            <jats:italic>aa<\/jats:italic>\n            <jats:sub>3<\/jats:sub>\n            ,\n            <jats:italic>b, c<\/jats:italic>\n            , and\n            <jats:italic>c<\/jats:italic>\n            <jats:sub>1<\/jats:sub>\n            , the cellular content of unsaturated fatty acids and ergosterol, and the activity of respiratory enzyme complexes. The half-maximal levels of membrane-bound cytochromes\n            <jats:italic>aa<\/jats:italic>\n            <jats:sub>3<\/jats:sub>\n            ,\n            <jats:italic>b<\/jats:italic>\n            , and\n            <jats:italic>c<\/jats:italic>\n            <jats:sub>1<\/jats:sub>\n            , were reached in cells grown in O\n            <jats:sub>2<\/jats:sub>\n            concentrations around 0.1 \u03bcM; this was similar to the oxygen concentration required for half-maximal levels of unsaturated fatty acid and sterol. However, the synthesis of ubiquinone and cytochrome\n            <jats:italic>c<\/jats:italic>\n            and the increase in fumarase activity were essentially linear functions of the dissolved oxygen concentration up to 3.5 \u03bcM oxygen. The synthesis of the succinate dehydrogenase, succinate cytochrome\n            <jats:italic>c<\/jats:italic>\n            reductase, and cytochrome\n            <jats:italic>c<\/jats:italic>\n            oxidase complexes showed different responses to changes in O\n            <jats:sub>2<\/jats:sub>\n            concentration in the growth medium. Cyanide-insensitive respiration and P\n            <jats:sub>450<\/jats:sub>\n            cytochrome content were maximal at 0.25 \u03bcM oxygen and declined in both more anaerobic and aerobic conditions. Cytochrome\n            <jats:italic>c<\/jats:italic>\n            peroxidase and catalase activities in cell-free homogenates were high in all but the most strictly anaerobic cells.\n          <\/jats:p>","DOI":"10.1128\/jb.115.1.88-97.1973","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T14:52:36Z","timestamp":1578063156000},"page":"88-97","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":48,"title":["Respiratory Development in\n            <i>Saccharomyces cerevisiae<\/i>\n            Grown at Controlled Oxygen Tension"],"prefix":"10.1128","volume":"115","author":[{"given":"P. J.","family":"Rogers","sequence":"first","affiliation":[{"name":"Department of Developmental Biology, Research School of Biological Sciences, Australian National University, Canberra, 2601, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Research School of Biological Sciences, Australian National University, Canberra, 2601, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jb.115.1.88-97.1973","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jb.115.1.88-97.1973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T17:07:42Z","timestamp":1627578462000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jb.115.1.88-97.1973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,7]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1973,7]]}},"alternative-id":["10.1128\/jb.115.1.88-97.1973"],"URL":"https:\/\/doi.org\/10.1128\/jb.115.1.88-97.1973","relation":{},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"value":"0021-9193","type":"print"},{"value":"1098-5530","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,7]]},"assertion":[{"value":"2021-02-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}