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Chemotaxis toward serine, arginine, and alpha-aminoisobutyrate was sharply dependent on the form in which nitrogen was presented to the bacteria. Bacteria grown on mineral salts-succinate with potassium nitrate gave responses to amino acids that were 2 to 3 times those of cells grown on ammonium sulfate and 10 to 20 times those of cells grown in mineral salts-succinate with Casamino Acids as the nitrogen source. A combination of ammonium sulfate and glutamate was as effective as Casamino Acids in depressing serine taxis. The threshold concentration for alpha-aminoisobutyrate taxis was consistently lower in nitrate-grown bacteria than in ammonia-grown bacteria. Responsiveness to sodium succinate, however, was not subject to regulation by nitrogen, and glucose chemotaxis was inhibited, rather than enhanced, in nitrate-grown bacteria. These results indicate that chemotaxis of P. aeruginosa toward amino acids is subject to regulation by nitrogen and that this regulation probably is expressed at the level of the chemoreceptors or transducers.<\/jats:p>","DOI":"10.1128\/jb.164.2.544-549.1985","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T18:23:15Z","timestamp":1578075795000},"page":"544-549","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":34,"title":["Regulation of Pseudomonas aeruginosa chemotaxis by the nitrogen source"],"prefix":"10.1128","volume":"164","author":[{"given":"R","family":"Craven","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T C","family":"Montie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"4473","DOI":"10.1021\/bi00719a001","article-title":"Identification of the ribose binding protein as the receptor for ribose chemotaxis in Salmonella typhimurium","volume":"13","author":"Aksamit R.","year":"1974","unstructured":"Aksamit , R. 1974 . 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