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All suppressor mutations proved to be recessive, indicating that their effects were caused by loss of function; thus, the suppressors identify genes that are necessary to trigger the pleiotropic response when HisH and HisF are overproduced. Genetic mapping of the suppressor mutations identifies four novel loci on the Salmonella typhimurium genetic map. Mutations in osmH (min 49) behave as general suppressors that abolish all manifestations of the pleiotropic response. Mutations in sfiY (min 83) suppress cell division inhibition and thermosensitivity but not osmosensitivity. Mutations that suppress only cell division inhibition define another locus, sfiX (min 44). A fourth novel locus, sfiW (min 19), is also involved in cell division inhibition. The phenotype of sfiW mutations is in turn pleiotropic: they suppress cell division inhibition, make S. typhimurium unable to grow in minimal media, and cause slow growth and abnormal colony and cell shape. The inability of sfiW mutants to grow in minimal medium cannot be relieved by any known nutritional requirement or by the use of carbon sources other than glucose. The hierarchy of suppressor phenotypes and the existence of epistatic effects among suppressor mutations suggest a pathway-like model for the Hisc pleiotropic response.<\/jats:p>","DOI":"10.1128\/jb.177.17.4841-4850.1995","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T14:05:03Z","timestamp":1478700303000},"page":"4841-4850","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Suppression of the pleiotropic effects of HisH and HisF overproduction identifies four novel loci on the Salmonella typhimurium chromosome: osmH, sfiW, sfiX, and sfiY"],"prefix":"10.1128","volume":"177","author":[{"given":"A","family":"Flores","sequence":"first","affiliation":[{"name":"Departamento de Gen\u00e9tica, Universidad de Sevilla, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Casades\u00fas","sequence":"additional","affiliation":[{"name":"Departamento de Gen\u00e9tica, Universidad de Sevilla, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/j.1365-2958.1992.tb01529.x","article-title":"Processing of a polycistronic mRNA requires a 5~ cis element and active transcription","volume":"6","author":"Alifano P.","year":"1992","unstructured":"Alifano , P. , C. Piscitelli , V. Blasi , F. Rivellini , A. G. Nappo , C. B. Bruni , and M. S. Carlomagno . 1992 . Processing of a polycistronic mRNA requires a 5~ cis element and active transcription . Mol. Microbiol. 6 : 787 - 798 .","journal-title":"Mol. Microbiol."},{"key":"p_2","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1101\/SQB.1979.043.01.120","article-title":"Gene duplication in bacteria: alteration of gene dosage by sister-chromosome exchanges","volume":"43","author":"Anderson R. P.","year":"1979","unstructured":"Anderson , R. P. , and J. R. Roth . 1979 . Gene duplication in bacteria: alteration of gene dosage by sister-chromosome exchanges . Cold Spring Harbor Symp. Quant. Biol. 43 : 1083 - 1087 .","journal-title":"Cold Spring Harbor Symp. Quant. Biol."},{"key":"p_3","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1128\/jb.137.3.1271-1281.1979","article-title":"Positive selection of mutants with cell envelope defects in a Salmonella typhimurium strain hypersensitive to the products of genes hisH and hisF","volume":"137","author":"Ant\u00f3n D. N.","year":"1979","unstructured":"Ant\u00f3n , D. N. 1979 . Positive selection of mutants with cell envelope defects in a Salmonella typhimurium strain hypersensitive to the products of genes hisH and hisF . J. Bacteriol. 137 : 1271 - 1281 .","journal-title":"J. Bacteriol."},{"key":"p_4","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1128\/mr.54.2.130-197.1990","article-title":"Linkage map of Escherichia coli K-12, edition 8","volume":"54","author":"Bachmann B. J.","year":"1990","unstructured":"Bachmann , B. J. 1990 . Linkage map of Escherichia coli K-12, edition 8 . Microbiol. Rev. 54 : 130 - 197 .","journal-title":"Microbiol. Rev."},{"key":"p_5","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1002\/j.1460-2075.1992.tb05107.x","article-title":"IS10 transposase mutations that specifically alter target site recognition","volume":"11","author":"Bender J.","year":"1992","unstructured":"Bender , J. , and N. Kleckner . 1992 . IS10 transposase mutations that specifically alter target site recognition . EMBO J. 11 : 741 - 750 .","journal-title":"EMBO J."},{"key":"p_6","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1128\/jb.174.5.1673-1681.1992","article-title":"Rapid mapping in Salmonella typhimurium with Mud-P22 prophages","volume":"174","author":"Benson N. R.","year":"1992","unstructured":"Benson , N. R. , and B. S. Goldman . 1992 . Rapid mapping in Salmonella typhimurium with Mud-P22 prophages . J. Bacteriol. 174 : 1673 - 1681 .","journal-title":"J. Bacteriol."},{"key":"p_7","unstructured":"Berg C. M. D. E. Berg and E. A. Groisman. 1989. Transposable elements and the genetic engineering of bacteria p. 879-925. In D. E. Berg and M. M. Howe (ed.) Mobile DNA. American Society for Microbiology Washington D.C."},{"key":"p_8","doi-asserted-by":"crossref","first-page":"5610","DOI":"10.1128\/jb.172.10.5610-5616.1990","article-title":"Interaction between the minB locus and ftsZ","volume":"172","author":"Bi E.","year":"1990","unstructured":"Bi , E. , and J. F. Lutkenhaus . 1990 . Interaction between the minB locus and ftsZ . J. Bacteriol. 172 : 5610 - 5616 .","journal-title":"J. Bacteriol."},{"key":"p_9","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0092-8674(82)90455-X","article-title":"ZTP (5-amino-4-imidazole carboxamide riboside 5~-triphosphate): a proposed alarmone for 10-formyl-tetrahydrofolate deficiency","volume":"29","author":"Bochner B. R.","year":"1982","unstructured":"Bochner , B. R. , and B. N. Ames . 1982 . 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Proline over-production results in enhanced osmotolerance in Salmonella typhimurium . Mol. Gen. Genet. 182 : 82 - 86 .","journal-title":"Mol. Gen. Genet."},{"key":"p_18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1128\/mr.53.1.121-147.1989","article-title":"Physiological and genetic responses of bacteria to osmotic stress","volume":"53","author":"Csonka L. N.","year":"1989","unstructured":"Csonka , L. N. 1989 . Physiological and genetic responses of bacteria to osmotic stress . Microbiol. Rev. 53 : 121 - 147 .","journal-title":"Microbiol. Rev."},{"key":"p_19","unstructured":"Davis R. W. D. Botstein and J. R. Roth. 1980. Advanced bacterial genetics. Cold Spring Harbor Laboratory Press Cold Spring Harbor N.Y."},{"key":"p_20","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1128\/jb.170.5.2106-2112.1988","article-title":"Isolation and properties of minB, a complex genetic locus involved in correct placement of the division site in Escherichia coli","volume":"170","author":"De Boer P. A. J.","year":"1988","unstructured":"De Boer , P. A. J. , R. E. Crossley , and L. I. Rothfield . 1988 . Isolation and properties of minB, a complex genetic locus involved in correct placement of the division site in Escherichia coli . J. Bacteriol. 170 : 2106 - 2112 .","journal-title":"J. Bacteriol."},{"key":"p_21","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/264328a0","article-title":"Cell length, cell growth and cell division","volume":"264","author":"Donachie W. D.","year":"1976","unstructured":"Donachie , W. D. , K. J. Begg , and M. Vicente . 1976 . Cell length, cell growth and cell division . 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R.","year":"1967","unstructured":"Fink , G. R. , T. Klopotowski , and B. N. Ames . 1967 . Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constitutive mutants . J. Mol. Biol. 30 : 81 - 95 .","journal-title":"J. Mol. Biol."},{"key":"p_25","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1007\/BF00280387","article-title":"The pleiotropic effects of Salmonella typhimurium his overexpression do not involve AICAR-induced mutagenesis","volume":"240","author":"Flores A.","year":"1993","unstructured":"Flores , A. , M. Fox , and J. Casades\u00fas . 1993 . The pleiotropic effects of Salmonella typhimurium his overexpression do not involve AICAR-induced mutagenesis . Mol. Gen. Genet. 240 : 360 - 364 .","journal-title":"Mol. Gen. Genet."},{"key":"p_26","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/BF00280386","article-title":"AICAR is not an endogenous mutagen in Escherichia coli","volume":"240","author":"Fox M.","year":"1993","unstructured":"Fox , M. , N. Frandsen , and R. D'Ari . 1993 . AICAR is not an endogenous mutagen in Escherichia coli . Mol. Gen. Genet. 240 : 355 - 359 .","journal-title":"Mol. Gen. Genet."},{"key":"p_27","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/BF00280385","article-title":"Excess histidine enzymes cause AICARindependent filamentation in Escherichia coli","volume":"240","author":"Frandsen N.","year":"1993","unstructured":"Frandsen , N. , and R. D'Ari . 1993 . Excess histidine enzymes cause AICARindependent filamentation in Escherichia coli . Mol. Gen. Genet. 240 : 348 - 354 .","journal-title":"Mol. Gen. Genet."},{"key":"p_28","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1574-6968.1990.tb04230.x","article-title":"sulA-independent division inhibition in His-constitutive strains of Salmonella typhimurium","volume":"69","author":"Gibert I.","year":"1990","unstructured":"Gibert , I. , and J. Casades\u00fas . 1990 . sulA-independent division inhibition in His-constitutive strains of Salmonella typhimurium . FEMS Microbiol. Lett. 69 : 205 - 210 .","journal-title":"FEMS Microbiol. Lett."},{"key":"p_29","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1128\/jb.100.1.215-219.1969","article-title":"Compounds which serve as the sole source of carbon or nitrogen for Salmonella typhimurium LT-2","volume":"100","author":"Gutnick D.","year":"1969","unstructured":"Gutnick , D. , J. M. Calvo , T. Klopotowski , and B. N. Ames . 1969 . Compounds which serve as the sole source of carbon or nitrogen for Salmonella typhimurium LT-2 . J. Bacteriol. 100 : 215 - 219 .","journal-title":"J. Bacteriol."},{"key":"p_30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2660(08)60170-4","article-title":"Mechanisms of suppression","volume":"17","author":"Hartman P. E.","year":"1973","unstructured":"Hartman , P. E. , and J. R. Roth . 1973 . Mechanisms of suppression . Adv. Genet. 17 : 1 - 105 .","journal-title":"Adv. Genet."},{"key":"p_31","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1128\/jb.99.1.274-278.1969","article-title":"Transduction of merodiploidy: induced duplication of recipient genes","volume":"99","author":"Hill C. W.","year":"1969","unstructured":"Hill , C. W. , D. Schiffer , and P. Berg . 1969 . Transduction of merodiploidy: induced duplication of recipient genes . J. Bacteriol. 99 : 274 - 278 .","journal-title":"J. Bacteriol."},{"key":"p_32","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1128\/jb.159.1.130-137.1984","article-title":"Conditionally transposition-defective derivative of MudI(Amp Lac)","volume":"159","author":"Hughes K. T.","year":"1984","unstructured":"Hughes , K. T. , and J. R. Roth . 1984 . Conditionally transposition-defective derivative of MudI(Amp Lac) . J. Bacteriol. 159 : 130 - 137 .","journal-title":"J. Bacteriol."},{"key":"p_33","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/genetics\/109.2.263","article-title":"Directed formation of deletions and duplications using Mud(Ap, lac)","volume":"109","author":"Hughes K. T.","year":"1985","unstructured":"Hughes , K. T. , and J. R. Roth . 1985 . Directed formation of deletions and duplications using Mud(Ap, lac) . Genetics 109 : 263 - 282 .","journal-title":"Genetics"},{"key":"p_34","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/genetics\/119.1.9","article-title":"Transitory cis complementation: a method for providing transposition functions to defective transposons","volume":"119","author":"Hughes K. T.","year":"1988","unstructured":"Hughes , K. T. , and J. R. Roth . 1988 . Transitory cis complementation: a method for providing transposition functions to defective transposons . Genetics 119 : 9 - 12 .","journal-title":"Genetics"},{"key":"p_35","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0076-6879(91)04009-D","article-title":"Uses of transposons with emphasis on Tn10","volume":"204","author":"Kleckner N.","year":"1991","unstructured":"Kleckner , N. , J. Bender , and S. Gottesman . 1991 . Uses of transposons with emphasis on Tn10 . Methods Enzymol. 204 : 139 - 180 .","journal-title":"Methods Enzymol."},{"key":"p_36","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0022-2836(77)90123-1","article-title":"Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics","volume":"116","author":"Kleckner N.","year":"1977","unstructured":"Kleckner , N. , J. Roth , and D. Botstein . 1977 . Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics . J. Mol. Biol. 116 : 125 - 159 .","journal-title":"J. Mol. Biol."},{"key":"p_37","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1021\/bi00574a041","article-title":"Electrolyte effects on the activity of mutant enzymes in vivo and in vitro","volume":"18","author":"Kohno T.","year":"1979","unstructured":"Kohno , T. , and J. R. Roth . 1979 . Electrolyte effects on the activity of mutant enzymes in vivo and in vitro . Biochemistry 18 : 1386 - 1392 .","journal-title":"Biochemistry"},{"key":"p_38","unstructured":"Maloy S. R. 1990. Experimental techniques in bacterial genetics. Jones and Bartlett Publishers Boston."},{"key":"p_39","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1128\/jb.145.2.1110-1111.1981","article-title":"Selection for loss of tetracycline resistance by Escherichia coli","volume":"145","author":"Maloy S. R.","year":"1981","unstructured":"Maloy , S. R. , and W. D. Nunn . 1981 . Selection for loss of tetracycline resistance by Escherichia coli . J. Bacteriol. 145 : 1110 - 1112 . (Erratum, 146: 831.)","journal-title":"J. Bacteriol."},{"key":"p_40","unstructured":"Miller J. H. 1972. Experiments in molecular genetics p. 352-355. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y."},{"key":"p_41","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/0092-8674(83)90066-1","article-title":"Tn10 transposase acts preferentially on nearby transposon ends in vivo","volume":"32","author":"Morisato D.","year":"1983","unstructured":"Morisato , D. , J. C. Way , H. J. Kim , and N. Kleckner . 1983 . Tn10 transposase acts preferentially on nearby transposon ends in vivo . Cell 32 : 799 - 807 .","journal-title":"Cell"},{"key":"p_42","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1139\/m72-105","article-title":"Overproduction of hisH and hisF gene products leads to inhibition of cell division in Salmonella","volume":"18","author":"Murray M. L.","year":"1971","unstructured":"Murray , M. L. , and P. E. Hartman . 1971 . Overproduction of hisH and hisF gene products leads to inhibition of cell division in Salmonella . Can. J. Microbiol. 18 : 671 - 681 .","journal-title":"Can. J. Microbiol."},{"key":"p_43","unstructured":"Neuhard J. and P. Nygaard. 1987. Purines and pyrimidines p. 445-473. In F. C. Neidhardt J. L. Ingraham K. B. Low B. Magasanik M. Schaechter and H. E. Umbarger (ed.) Escherichia coli and Salmonella typhimurium: cellular and molecular biology. American Society for Microbiology Washington D.C."},{"key":"p_44","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1042\/bj1060271","article-title":"Biosynthesis of the pyrimidine moiety of thiamine","volume":"106","author":"Newell P. C.","year":"1968","unstructured":"Newell , P. C. , and R. G. Tucker . 1968 . Biosynthesis of the pyrimidine moiety of thiamine . Biochem. J. 106 : 279 - 287 .","journal-title":"Biochem. J."},{"key":"p_45","unstructured":".Roberts G. Unpublished data."},{"key":"p_46","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0022-2836(71)90204-X","article-title":"Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli","volume":"61","author":"Rupp W. D.","year":"1971","unstructured":"Rupp , W. D. , C. E. Wilde III , D. L. Reno , and P. Howard-Flanders . 1971 . Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli . J. Mol. Biol. 61 : 25 - 44 .","journal-title":"J. Mol. Biol."},{"key":"p_47","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1126\/science.6199843","article-title":"The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP)","volume":"223","author":"Sabina R. L.","year":"1984","unstructured":"Sabina , R. L. , E. W. Holmes , and M. A. Becker . 1984 . The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP) . Science 223 : 1193 - 1195 .","journal-title":"Science"},{"key":"p_48","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1128\/mr.52.4.485-532.1988","article-title":"Linkage map of Salmonella typhimurium, edition VII","volume":"52","author":"Sanderson K. E.","year":"1988","unstructured":"Sanderson , K. E. , and J. R. Roth . 1988 . Linkage map of Salmonella typhimurium, edition VII . Microbiol. Rev. 52 : 485 - 532 .","journal-title":"Microbiol. Rev."},{"key":"p_49","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1128\/jb.153.2.1114-1119.1983","article-title":"Internal promoters of the his operon in Salmonella typhimurium","volume":"153","author":"Schmid M. B.","year":"1983","unstructured":"Schmid , M. B. , and J. R. Roth . 1983 . Internal promoters of the his operon in Salmonella typhimurium . J. Bacteriol. 153 : 1114 - 1119 .","journal-title":"J. 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