{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T07:25:40Z","timestamp":1791098740560,"version":"4.1.0"},"reference-count":51,"publisher":"American Society for Microbiology","issue":"13","license":[{"start":{"date-parts":[[2002,7,1]],"date-time":"2002-07-01T00:00:00Z","timestamp":1025481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Xanthomonadins are membrane-bound, brominated, aryl-polyene pigments specific to the genus\n            <jats:italic>Xanthomonas<\/jats:italic>\n            . We have characterized a genetic locus (\n            <jats:italic>pig<\/jats:italic>\n            ) from\n            <jats:italic>Xanthomonas oryzae<\/jats:italic>\n            pv. oryzae which contains four open reading frames (ORFs) that are essential for xanthomonadin production. Three of these ORFs are homologous to acyl carrier proteins, dehydratases, and acyl transferases, suggesting a type II polyketide synthase pathway for xanthomonadin biosynthesis. The fourth ORF has no homologue in the database. For the first time, we report that a putative cytoplasmic membrane protein encoded in the\n            <jats:italic>pig<\/jats:italic>\n            locus is required for outer membrane localization of xanthomonadin in\n            <jats:italic>X. oryzae<\/jats:italic>\n            pv. oryzae. We also report the identification of a novel 145-bp palindromic\n            <jats:italic>Xanthomonas<\/jats:italic>\n            repetitive intergenic consensus element that is present in two places in the\n            <jats:italic>pig<\/jats:italic>\n            locus. We estimate that more than 100 copies of this element might be present in the genome of\n            <jats:italic>X. oryzae<\/jats:italic>\n            pv. oryzae and other xanthomonads.\n          <\/jats:p>","DOI":"10.1128\/jb.184.13.3539-3548.2002","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:09:14Z","timestamp":1027764554000},"page":"3539-3548","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":68,"title":["Genetic Locus Encoding Functions Involved in Biosynthesis and Outer Membrane Localization of Xanthomonadin in\n            <i>Xanthomonas oryzae<\/i>\n            pv. oryzae"],"prefix":"10.1128","volume":"184","author":[{"given":"Ajay Kumar","family":"Goel","sequence":"first","affiliation":[{"name":"Centre for Cellular and Molecular Biology, Hyderabad 500 007, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi","family":"Rajagopal","sequence":"additional","affiliation":[{"name":"Centre for Cellular and Molecular Biology, Hyderabad 500 007, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narayana","family":"Nagesh","sequence":"additional","affiliation":[{"name":"Centre for Cellular and Molecular Biology, Hyderabad 500 007, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh V.","family":"Sonti","sequence":"additional","affiliation":[{"name":"Centre for Cellular and Molecular Biology, Hyderabad 500 007, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/25.17.3389"},{"key":"e_1_3_2_3_2","first-page":"4023","volume":"45","year":"1976","unstructured":"Andrewes, A. 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