{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T06:31:40Z","timestamp":1715149900902},"reference-count":24,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The RdgC protein of\n            <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n            is required for efficient pilin antigenic variation, although its precise role has yet to be established. We demonstrate that the nearly identical RdgC from\n            <jats:italic>Neisseria meningitidis<\/jats:italic>\n            binds DNA with little specificity for sequence or structure, like the\n            <jats:italic>Escherichia coli<\/jats:italic>\n            protein. We also show that neither protein is able to constrain torsional tension in relaxed DNA. These data exclude several possible roles for RdgC in pilin antigenic variation and suggest that RdgC performs a similar function in both\n            <jats:italic>E. coli<\/jats:italic>\n            and the\n            <jats:italic>Neisseria<\/jats:italic>\n            spp.\n          <\/jats:p>","DOI":"10.1128\/jb.186.3.870-874.2004","type":"journal-article","created":{"date-parts":[[2004,1,16]],"date-time":"2004-01-16T19:37:50Z","timestamp":1074281870000},"page":"870-874","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["DNA Binding by the Meningococcal RdgC Protein, Associated with Pilin Antigenic Variation"],"prefix":"10.1128","volume":"186","author":[{"given":"Timothy","family":"Moore","sequence":"first","affiliation":[{"name":"Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary J.","family":"Sharples","sequence":"additional","affiliation":[{"name":"Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert G.","family":"Lloyd","sequence":"additional","affiliation":[{"name":"Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s004380000356","volume":"264","year":"2001","unstructured":"Barten, R., and T. 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