{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:42:07Z","timestamp":1791027727527,"version":"4.1.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2006,5,15]],"date-time":"2006-05-15T00:00:00Z","timestamp":1147651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2006,5,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A DNA microarray was used to identify genes transcribed in\n                    <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n                    using Ecf, an alternative sigma factor. No differences between the transcriptional profiles of strain FA1090 and a mutant where\n                    <jats:italic>ecf<\/jats:italic>\n                    had been inactivated could be detected when both were grown in vitro. We therefore constructed a gonococcal strain in which Ecf can be overexpressed. Some differentially expressed genes are clustered with\n                    <jats:italic>ecf<\/jats:italic>\n                    on the genome and appear to form a single transcriptional unit. Expression of the gene encoding MsrAB, which possesses methionine sulfoxide reductase activity, was also dependent on Ecf, suggesting that the regulon responds to oxidative damage. Western blotting confirmed that the increased level of MsrAB protein is dependent on the presence of Ecf.\n                  <\/jats:p>","DOI":"10.1128\/jb.188.10.3463-3469.2006","type":"journal-article","created":{"date-parts":[[2006,5,3]],"date-time":"2006-05-03T15:26:32Z","timestamp":1146669992000},"page":"3463-3469","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":30,"title":["Ecf, an Alternative Sigma Factor from\n                    <i>Neisseria gonorrhoeae<\/i>\n                    , Controls Expression of\n                    <i>msrAB<\/i>\n                    , Which Encodes Methionine Sulfoxide Reductase"],"prefix":"10.1128","volume":"188","author":[{"given":"Ishara C.","family":"Gunesekere","sequence":"first","affiliation":[{"name":"Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Clayton, VIC 3800, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene M.","family":"Kahler","sequence":"additional","affiliation":[{"name":"Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Clayton, VIC 3800, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine S.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Clayton, VIC 3800, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori A. S.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Bacterial Pathogenesis and Functional Genomics Group, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel J.","family":"Saunders","sequence":"additional","affiliation":[{"name":"Bacterial Pathogenesis and Functional Genomics Group, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian I.","family":"Rood","sequence":"additional","affiliation":[{"name":"Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Clayton, VIC 3800, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K.","family":"Davies","sequence":"additional","affiliation":[{"name":"Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Clayton, VIC 3800, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.meegid.2004.04.003","volume":"4","year":"2004","unstructured":"Bashyam, M. 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