{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T08:47:38Z","timestamp":1790930858499,"version":"4.1.0"},"reference-count":17,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2006,2,15]],"date-time":"2006-02-15T00:00:00Z","timestamp":1139961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2006,2,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    We identified two regulators of denitrification genes in\n                    <jats:italic>Brucella melitensis<\/jats:italic>\n                    16M: NarR, which regulates the nitrate reductase (\n                    <jats:italic>nar<\/jats:italic>\n                    ) operon, and NnrA, which is involved in the expression of the last three reductases of the denitrification pathway (\n                    <jats:italic>nirK<\/jats:italic>\n                    ,\n                    <jats:italic>norB<\/jats:italic>\n                    , and\n                    <jats:italic>nosZ<\/jats:italic>\n                    ). NnrA is required for virulence in mice and for intracellular resistance to nitric oxide.\n                  <\/jats:p>","DOI":"10.1128\/jb.188.4.1615-1619.2006","type":"journal-article","created":{"date-parts":[[2006,2,1]],"date-time":"2006-02-01T14:40:30Z","timestamp":1138804830000},"page":"1615-1619","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":62,"title":["NnrA Is Required for Full Virulence and Regulates Several\n                    <i>Brucella melitensis<\/i>\n                    Denitrification Genes"],"prefix":"10.1128","volume":"188","author":[{"given":"Vale\u0301rie","family":"Haine","sequence":"first","affiliation":[{"name":"Unite\u0301 de Recherche en Biologie Mole\u0301culaire (URBM), University of Namur, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Dozot","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Recherche en Biologie Mole\u0301culaire (URBM), University of Namur, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Dornand","sequence":"additional","affiliation":[{"name":"INSERM U431, University of Montpellier II, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Jacques","family":"Letesson","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Recherche en Biologie Mole\u0301culaire (URBM), University of Namur, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"De Bolle","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Recherche en Biologie Mole\u0301culaire (URBM), University of Namur, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.184.11.2987-2993.2002"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1099\/00221287-148-3-825","volume":"148","year":"2002","unstructured":"Bartnikas, T. 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