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Bacteriol.<jats:bold>82:<\/jats:bold>284\u2013287. 1961.\u2014Germ-free guinea pigs succumb after oral infection with<jats:italic>Shigella flexneri<\/jats:italic>serotype 2a; they survive a similar challenge with either a strain of<jats:italic>Escherichia coli<\/jats:italic>or a culture of lactobacillus. Animals monocontaminated with<jats:italic>E. coli<\/jats:italic>survive, whereas those monocontaminated with lactobacilli succumb to subsequent challenge with dysentery bacilli. Prior subcutaneous inoculation of heat-killed<jats:italic>S. flexneri<\/jats:italic>2a does not render germ-free guinea pigs resistant to the fatal infection with viable dysentery bacilli.<\/jats:p>","DOI":"10.1128\/jb.82.2.284-287.1961","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T21:20:08Z","timestamp":1578086408000},"page":"284-287","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":44,"title":["EXPERIMENTAL SHIGELLA INFECTIONS V"],"prefix":"10.1128","volume":"82","author":[{"given":"Samuel B.","family":"Formal","sequence":"first","affiliation":[{"name":"Walter Reed Army Institute of Research, Washington, D. 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