{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T01:34:52Z","timestamp":1648517692420},"reference-count":15,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[1962,7,1]],"date-time":"1962-07-01T00:00:00Z","timestamp":-236822400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[1962,7]]},"abstract":"<jats:p>\n            <jats:sc>Converse<\/jats:sc>\n            , J. L. (U. S. Army Chemical Corps, Frederick, Md.), M. W.\n            <jats:sc>Castleberry, A. R. Besemer, and E. M. Snyder<\/jats:sc>\n            . Immunization of mice against coccidioidomycosis. J. Bacteriol.\n            <jats:bold>84:<\/jats:bold>\n            46\u201352. 1962\u2014The observed lower virulence of\n            <jats:italic>Coccidioides immitis<\/jats:italic>\n            arthrospores of the M-11 strain compared with the Cash strain was ascribed to the lower ability of the M-11 spores to invade the lungs and brain. Endospores of strain M-11, grown in synthetic medium, were equally as virulent by the intraperitoneal route as arthrospores of strain Cash. Immunization of mice with viable strain M-11 arthrospores protected approximately 50% of the animals against challenge with strain Cash arthrospores. This was evidenced by lower mortality over a 5-month period and lack of gross pathological lesions in killed animals. Although fewer lesions resulted after the use of a viable vaccine, higher survival was obtained with formaldehyde-killed arthrospores. Either preparation tended to confine the infection to the peritoneal cavity.\n          <\/jats:p>","DOI":"10.1128\/jb.84.1.46-52.1962","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T21:22:34Z","timestamp":1578086554000},"page":"46-52","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["IMMUNIZATION OF MICE AGAINST COCCIDIOIDOMYCOSIS"],"prefix":"10.1128","volume":"84","author":[{"given":"J. L.","family":"Converse","sequence":"first","affiliation":[{"name":"U.S. Army Chemical Corps, Fort Detrick, Frederick, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. W.","family":"Castleberry","sequence":"additional","affiliation":[{"name":"U.S. Army Chemical Corps, Fort Detrick, Frederick, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. R.","family":"Besemer","sequence":"additional","affiliation":[{"name":"U.S. Army Chemical Corps, Fort Detrick, Frederick, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. M.","family":"Snyder","sequence":"additional","affiliation":[{"name":"U.S. Army Chemical Corps, Fort Detrick, Frederick, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1128\/JB.74.1.106-107.1957","article-title":"Effect of surface active agents on endosporulation of Coccidioides immitis in a chemically defined medium","volume":"74","author":"CONVERSE J. L.","year":"1957","unstructured":"CONVERSE , J. L. 1957 . Effect of surface active agents on endosporulation of Coccidioides immitis in a chemically defined medium . J. Bacteriol. 74 : 106 - 107 .","journal-title":"J. Bacteriol."},{"key":"p_2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1128\/JB.83.4.871-878.1962","article-title":"Pathogenesis of Coccidioides immitis in monkeys","volume":"83","author":"CONVERSE J. L.","year":"1962","unstructured":"CONVERSE , J. L. , E. P. LOWE , M. W. CASTLEBERRY , G. P. BLUNDELL , A ND A . R. BESEMER. 1962 . Pathogenesis of Coccidioides immitis in monkeys . J. Bacteriol. 83 : 871 - 878 .","journal-title":"J. Bacteriol."},{"key":"p_3","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/JB.79.4.480-487.1960","article-title":"X-ray irradiation of Coccidioides immitis arthrospores: survival curves and avirulent mutants isolated","volume":"79","author":"FOLEY J. M.","year":"1960","unstructured":"FOLEY , J. M. , R. J. BERMAN , A ND C . E. SMITH. 1960 . X-ray irradiation of Coccidioides immitis arthrospores: survival curves and avirulent mutants isolated . J. Bacteriol. 79 : 480 - 487 .","journal-title":"J. Bacteriol."},{"key":"p_4","first-page":"245","article-title":"Vaccination of mice against Coccidioides immitis","volume":"74","author":"FRIEDMAN L.","year":"1956","unstructured":"FRIEDMAN , L. , AND C. E. SMITH. 1956 . Vaccination of mice against Coccidioides immitis . Am. Rev. Tuberc. Pulmonary Diseases 74 : 245 - 248 .","journal-title":"Am. Rev. Tuberc. Pulmonary Diseases"},{"key":"p_5","first-page":"198","article-title":"The virulence and infectivity of twenty-seven strains of Coccidioides immitis","volume":"64","author":"FRIEDMAN L., C.","year":"1956","unstructured":"FRIEDMAN , L., C. E. SMITH , W. G. ROESSLER , A ND J . BERMAN. 1956 . The virulence and infectivity of twenty-seven strains of Coccidioides immitis . Am. J. Hyg. 64 : 198 - 210 .","journal-title":"Am. J. Hyg."},{"key":"p_6","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/j.2164-0947.1960.tb00711.x","article-title":"Immunity of coccidioidomycosis induced in mice by purified spherule, arthrospores, and mycelial vaccines","volume":"22","author":"LEVINE H. B.","year":"1960","unstructured":"LEVINE , H. B. , J. M. COBB , A ND C . E. SMITH. 1960 . Immunity of coccidioidomycosis induced in mice by purified spherule, arthrospores, and mycelial vaccines . Trans. N. Y. Acad. Sci. 22 : 436 - 449 .","journal-title":"Trans. N. Y. Acad. Sci."},{"key":"p_7","unstructured":"LOWE E. P. J. L. CONVERSE G. P. BLUNDELL AND M. W. CASTLEBERRY. 1959. Experimental respiratory infection with Coccidioides immitis in the monkey. Proc. Annual VA-Armed Forces Cooperative Coccidioidomycosis Study Group Los Angeles Calif. p. 14-15."},{"key":"p_8","first-page":"273","article-title":"Estudios sobre el Coccidioides immitis Rixford et Gilchrist. VII. Reacciones immunoalergicas en la infeccion experimental del cobayo","volume":"14","author":"NEGRONI P., D.","year":"1949","unstructured":"NEGRONI , P., D. VIVOLI , A ND H . BONFIGLIOLI. 1949 . Estudios sobre el Coccidioides immitis Rixford et Gilchrist. VII. Reacciones immunoalergicas en la infeccion experimental del cobayo . Rev. Inst. Malbra,n (Buenos Aires) 14 : 273 - 286 .","journal-title":"Rev. Inst. Malbra,n (Buenos Aires)"},{"key":"p_9","first-page":"589","article-title":"Experimental subcutaneous coccidioidal infection in the mouse","volume":"32","author":"PAPPAGIANIS D., C.","year":"1959","unstructured":"PAPPAGIANIS , D., C. E. SMITH , R. J. BERMAN , A ND G . S. KOBAYASHI. 1959 . Experimental subcutaneous coccidioidal infection in the mouse . J. Invest. Dermatol. 32 : 589 - 598 .","journal-title":"J. Invest. Dermatol."},{"key":"p_10","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/infdis\/98.3.312","article-title":"Relationship of the in vivo form of Coccidioides immitis to virulence","volume":"98","author":"PAPPAGIANIS D., C.","year":"1956","unstructured":"PAPPAGIANIS , D., C. E. SMITH , A ND G . S. KOBAYASHI. 1956 . Relationship of the in vivo form of Coccidioides immitis to virulence . J. Infectious Diseases 98 : 312 - 319 .","journal-title":"J. Infectious Diseases"},{"key":"p_11","first-page":"209","article-title":"Two cases of protozoan (coccidioidal) infection of the skin and other organs","volume":"1","author":"RIXFORD E.","year":"1896","unstructured":"RIXFORD , E. , AND T. C. GILCHRIST. 1896 . Two cases of protozoan (coccidioidal) infection of the skin and other organs . Johns Hopkins Hosp. Rept. 1 : 209 - 268 .","journal-title":"Johns Hopkins Hosp. Rept."},{"key":"p_12","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/infdis\/79.1.12","article-title":"Studies with Coccidioides immitis. I. Submerged growth in liquid mediums","volume":"79","author":"ROESSLER W. G.","year":"1946","unstructured":"ROESSLER , W. G. , E. J. HERBST , W. G. MCCULLOUGH , R. C. MILLS , A ND C . R. BREWER. 1946 . Studies with Coccidioides immitis. I. Submerged growth in liquid mediums . J. Infectious Diseases 79 : 12 - 22 .","journal-title":"J. Infectious Diseases"},{"key":"p_13","unstructured":"SMITH C. E. 1951. Annual progress report. Commission on Acute Respiratory Diseases. Armed Forces Epidemiological Board Washington D.C."},{"issue":"575","key":"p_14","first-page":"3","article-title":"The public health significance of coccidioidomycosis. U.S. Public Health Serv","author":"SMITH C. E.","year":"1957","unstructured":"SMITH , C. E. , D. PAPPAGIANIS , A ND M . SATO. 1957 . The public health significance of coccidioidomycosis. U.S. Public Health Serv ., Public Health Serv. Publ. no. 575 , p. 3 - 9 .","journal-title":"Public Health Serv. Publ."},{"key":"p_15","first-page":"498","article-title":"Preliminary studies on artificial active immunization of guinea pigs against respiratory challenge with Coccidioides immitis","volume":"79","author":"VOGEL R. A.","year":"1954","unstructured":"VOGEL , R. A. , B. F. FETTER , N. F. CONANT , A ND E . P. LOWE. 1954 . Preliminary studies on artificial active immunization of guinea pigs against respiratory challenge with Coccidioides immitis . Am. Rev. Tuberc. 79 : 498 - 503 .","journal-title":"Am. Rev. 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