{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T21:52:02Z","timestamp":1790977922078,"version":"4.1.0"},"reference-count":21,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[1966,3,1]],"date-time":"1966-03-01T00:00:00Z","timestamp":-121132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[1966,3]]},"abstract":"<jats:p>\n            <jats:sc>London, Jack<\/jats:sc>\n            (University of California, Los Angeles),\n            <jats:sc>and Sydney C. Rittenberg<\/jats:sc>\n            . Effects of organic matter on the growth of\n            <jats:italic>Thiobacillus intermedius<\/jats:italic>\n            . J. Bacteriol.\n            <jats:bold>91:<\/jats:bold>\n            1062\u20131069. 1966.\u2014Yeast extract, glucose, glutamate, and other organic materials stimulate the rate and extent of growth of\n            <jats:italic>Thiobacillus intermedius<\/jats:italic>\n            in thiosulfate broth. Growth did not occur in glucose or glutamate mineral salts medium in the absence of thiosulfate, although a stable variant was obtained which grows on yeast extract alone. Cells harvested from media supplemented with organic matter have a reduced rate of thiosulfate oxidation (20 to 30% of autotrophic), oxidize the organic supplement, and have an additive rate of oxidation in the presence of both the organic substrate and thiosulfate. Carboxydismutase synthesis is repressed, and the incorporation of bicarbonate carbon into cell material is almost completely eliminated by the presence of organic matter in the growth medium. It is concluded that the availability of organic matter eliminates the autotrophic assimilatory mechanisms of\n            <jats:italic>T. intermedius<\/jats:italic>\n            but not its autotrophic energy-generating system. The data are discussed in relation to the existence of \u201cobligate\u201d chemoautotrophic bacteria.\n          <\/jats:p>","DOI":"10.1128\/jb.91.3.1062-1069.1966","type":"journal-article","created":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T01:51:45Z","timestamp":1578189105000},"page":"1062-1069","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":63,"title":["Effects of Organic Matter on the Growth of\n            <i>Thiobacillus intermedius<\/i>"],"prefix":"10.1128","volume":"91","author":[{"given":"Jack","family":"London","sequence":"first","affiliation":[{"name":"Department of Bacteriology, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney C.","family":"Rittenberg","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1128\/jb.90.1.102-107.1965","article-title":"Carbon and energy sources for the nitrifying autotroph Nitrobacter","volume":"90","author":"DELWICHE C. 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