{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T18:48:19Z","timestamp":1790966899147,"version":"4.1.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Invasive group A streptococcal (GAS) infections cause significant morbidity and mortality. A national survey was initiated to assess the burden of invasive GAS infections in France, describe their clinical characteristics, and assess the molecular characteristics of GAS strains responsible for these infections. The survey was conducted in 194 hospitals, accounting for 51% of acute care hospital admissions in France. Clinical data, predisposing factors, and demographic data were obtained, and all GAS isolates were\n            <jats:italic>emm<\/jats:italic>\n            sequence typed. We identified 664 cases of invasive GAS infections, with an annual incidence of 3.1 per 100,000 population. The case-fatality ratio was 14% and rose to 43% in the case of streptococcal toxic shock syndrome. Bacteremia without identified focus (22%) and skin\/soft tissue infections (30%) were the most frequent clinical presentations. Necrotizing fasciitis was frequent in adults (18%) and uncommon in children (3%). The 3 predominant\n            <jats:italic>emm<\/jats:italic>\n            types\n            <jats:italic>were emm<\/jats:italic>\n            1,\n            <jats:italic>emm<\/jats:italic>\n            89, and\n            <jats:italic>emm<\/jats:italic>\n            28, accounting for 33%, 16%, and 10% of GAS isolates, respectively. The\n            <jats:italic>emm<\/jats:italic>\n            1 type was associated with fatal outcomes and was more frequent in children than in adults. Six clusters of cases were identified, with each cluster involving 2 invasive cases due to GAS strains which shared identical GAS\n            <jats:italic>emm<\/jats:italic>\n            sequence types. Four clusters of cases involved eight postpartum infections, one family cluster involved a mother and child, and one cluster involved two patients in a nursing home. Invasive GAS infection is one of the most severe bacterial diseases in France, particularly in persons aged \u226550 years or when associated with toxic shock syndrome.\n          <\/jats:p>","DOI":"10.1128\/jcm.00070-11","type":"journal-article","created":{"date-parts":[[2011,10,6]],"date-time":"2011-10-06T00:53:59Z","timestamp":1317862439000},"page":"4094-4100","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":96,"title":["Epidemiology of Invasive Streptococcus pyogenes Infections in France in 2007"],"prefix":"10.1128","volume":"49","author":[{"given":"A.","family":"Lepoutre","sequence":"first","affiliation":[{"name":"French Institute for Public Health Surveillance, Saint Maurice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Doloy","sequence":"additional","affiliation":[{"name":"Assistance Publique H\u00f4pitaux de Paris, Service de Bact\u00e9riologie, Centre National de R\u00e9f\u00e9rence des Streptocoques, H\u00f4pital Cochin, Paris, France"},{"name":"Universit\u00e9 Paris Descartes, Paris, France"},{"name":"INSERM, U567, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Bidet","sequence":"additional","affiliation":[{"name":"Assistance Publique H\u00f4pitaux de Paris, Service de Bact\u00e9riologie, H\u00f4pital Robert Debr\u00e9, Paris, France"},{"name":"Universit\u00e9 Paris Diderot, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Leblond","sequence":"additional","affiliation":[{"name":"French Institute for Public Health Surveillance, Saint Maurice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Perrocheau","sequence":"additional","affiliation":[{"name":"French Institute for Public Health Surveillance, Saint Maurice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bingen","sequence":"additional","affiliation":[{"name":"Assistance Publique H\u00f4pitaux de Paris, Service de Bact\u00e9riologie, H\u00f4pital Robert Debr\u00e9, Paris, France"},{"name":"Universit\u00e9 Paris Diderot, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Trieu-Cuot","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unit\u00e9 de Biologie des Bact\u00e9ries Pathog\u00e8nes \u00e0 Gram Positif, URA CNRS 2172, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bouvet","sequence":"additional","affiliation":[{"name":"Assistance Publique H\u00f4pitaux de Paris, Service de Bact\u00e9riologie, Centre National de R\u00e9f\u00e9rence des Streptocoques, H\u00f4pital Cochin, Paris, France"},{"name":"Universit\u00e9 Paris Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Poyart","sequence":"additional","affiliation":[{"name":"Assistance Publique H\u00f4pitaux de Paris, Service de Bact\u00e9riologie, Centre National de R\u00e9f\u00e9rence des Streptocoques, H\u00f4pital Cochin, Paris, France"},{"name":"Universit\u00e9 Paris Descartes, Paris, France"},{"name":"INSERM, U567, Paris, France"},{"name":"Institut Pasteur, Unit\u00e9 de Biologie des Bact\u00e9ries Pathog\u00e8nes \u00e0 Gram Positif, URA CNRS 2172, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"L\u00e9vy-Bruhl","sequence":"additional","affiliation":[{"name":"French Institute for Public Health Surveillance, Saint Maurice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Microbiologists of the Epibac Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.4.953-958.1996"},{"key":"e_1_3_2_3_2","volume-title":"Surveillance des infections invasives \u00e0 m\u00e9ningocoque en France m\u00e9tropolitaine en 2005. \u00c9valuation quantitative par la m\u00e9thode de capture-recapture \u00e0 trois sources","author":"Berger F.","year":"2010","unstructured":"BergerF. BernillonP. GallayA. 2010. Surveillance des infections invasives \u00e0 m\u00e9ningocoque en France m\u00e9tropolitaine en 2005. \u00c9valuation quantitative par la m\u00e9thode de capture-recapture \u00e0 trois sources. Institut de Veille Sanitaire, Saint-Maurice. France. http:\/\/www.invs.sante.fr\/surveillance\/iim\/default.htm."},{"key":"e_1_3_2_4_2","volume-title":"Abstr. 9th Meet. Eur. Monitoring Group Meningococci","author":"Berger F.","year":"2007","unstructured":"BergerF.. 2007. Three-sources capture-recapture analysis to evaluate the comprehensiveness of reporting invasive meningococcal infections in France, poster 3. Abstr. 9th Meet. Eur. Monitoring Group Meningococci. http:\/\/www.invs.sante.fr\/surveillance\/iim\/poster_emgm_rome.pdf."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/444505"},{"key":"e_1_3_2_6_2","volume-title":"Guide pour la pr\u00e9vention et l'investigation des infections hospitali\u00e8res \u00e0 Streptococcus pyogenes","author":"Conseil Sup\u00e9rieur d'Hygi\u00e8ne Publique de France, Comit\u00e9 Technique des Infections Nosocomiales et des Infections Li\u00e9es aux Soins","year":"2006","unstructured":"Conseil Sup\u00e9rieur d'Hygi\u00e8ne Publique de France, Comit\u00e9 Technique des Infections Nosocomiales et des Infections Li\u00e9es aux Soins. 2006. Guide pour la pr\u00e9vention et l'investigation des infections hospitali\u00e8res \u00e0 Streptococcus pyogenes. Minist\u00e8re de la Sant\u00e9, Paris, France."},{"key":"e_1_3_2_7_2","unstructured":"Conseil Sup\u00e9rieur d'Hygi\u00e8ne Publique de France Section des Maladies Transmissibles. 2005. Avis relatif \u00e0 la conduite \u00e0 tenir autour d'un ou de plusieurs cas d'origine communautaire d'infections invasives \u00e0 Streptococcus pyogenes (ou streptocoques du groupe A) s\u00e9ance du 18 Novembre 2005. Minist\u00e8re de la Sant\u00e9 Paris France."},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/431589"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/519936"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199608223350803"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0706.010610"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00422-08"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1402.070888"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2008.02076.x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.13.35.18962-en"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02155-08"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01626-07"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1101.040559"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02808.x"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1086\/444458"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.8.3844-3846.2004"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/341409"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1086\/521264"},{"key":"e_1_3_2_24_2","first-page":"16","volume-title":"Bulletin epid\u00e9miologique hebdomadaire 2-3","author":"Perrocheau A.","year":"2006","unstructured":"PerrocheauA.. 2006. Estimation du nombre total de m\u00e9ningites \u00e0 pneumocoque de l'enfant par la m\u00e9thode capture-recapture \u00e0 3 sources, France, 2001-2002, p. 16-19. Bulletin epid\u00e9miologique hebdomadaire 2-3. Institut de Veille Sanitaire, Saint-Maurice, France. http:\/\/www.invs.sante.fr\/beh\/2006\/02_03\/beh_02_03_2006.pdf."},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1086\/502567"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0904.020369"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0195941700045677"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.4.1678-1683.2005"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-1825-3_21"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-004-1147-z"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01821.x"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03500030088038"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00070-11","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00070-11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T12:46:35Z","timestamp":1646484395000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.00070-11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1128\/JCM.00070-11"],"URL":"https:\/\/doi.org\/10.1128\/jcm.00070-11","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"2011-01-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-09-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-11-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}