{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T04:42:38Z","timestamp":1775709758445,"version":"3.50.1"},"reference-count":44,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2024,7,16]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              The Panbio COVID-19\/Flu A&amp;B Panel (Abbott) is an\n              <jats:italic>in vitro<\/jats:italic>\n              diagnostic rapid test designed for the qualitative detection of nucleocapsid proteins SARS-CoV-2 and nucleoprotein influenza A and B antigens in nasal mid-turbinate (NMT) swab specimens from symptomatic individuals meeting COVID-19 and influenza clinical and\/or epidemiological criteria. This study, the largest global one to date using fresh samples, aimed to assess the diagnostic sensitivity and specificity of the Panbio COVID-19\/Flu A&amp;B Panel in freshly collected NMT swab specimens from individuals suspected of respiratory viral infection consistent with COVID-19 and\/or influenza within the first 5 days of symptom onset compared with results obtained with the cobas SARS-CoV-2 and influenza A\/B qualitative assay (cobas 6800\/8800 systems), which were tested using nasopharyngeal swab samples. A total of 512 evaluable subjects were enrolled in the COVID-19 cohort across 18 sites, and 1,148 evaluable subjects were enrolled in the influenza cohort across 22 sites in the Asia-Pacific, Europe, and the USA. The Panbio COVID-19\/Flu A&amp;B Panel demonstrated a sensitivity of 80.4% and a specificity of 99.7% for COVID-19. For influenza A, the sensitivity and specificity rates were 80.6% and 99.3%, respectively. Likewise, for influenza B, the sensitivity and specificity rates were 80.8% and 99.4%, respectively. In conclusion, the Panbio COVID-19\/Flu A&amp;B Panel emerges as a suitable rapid test for detecting COVID-19 and influenza in symptomatic subjects across diverse global populations, exhibiting high sensitivity. The assay achieved a sensitivity of 94.4% in samples with Ct \u226424 for COVID-19 and 92.6% in samples with Ct \u226430 for influenza A and B.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>IMPORTANCE<\/jats:title>\n            <jats:p>The Panbio COVID-19\/Flu A&amp;B Panel is a suitable rapid test for detecting COVID-19 and influenza in symptomatic subjects across diverse global populations, exhibiting high sensitivity. The assay achieved a sensitivity of 94.0% in samples with Ct \u226424 for COVID-19 and 92.6% in samples with Ct \u226430 for influenza A and B.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/jcm.00207-24","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T13:01:09Z","timestamp":1718715669000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Performance evaluation of the Panbio COVID-19\/Flu A&amp;B Panel for detection of SARS-CoV-2, influenza A, and influenza B antigens using mid-turbinate nasal swabs"],"prefix":"10.1128","volume":"62","author":[{"given":"Shao-Hua","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keun-Ju","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Korea University College of Medicine, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Chang","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanely Pineiro","family":"Puebla","sequence":"additional","affiliation":[{"name":"Palm Springs Community Health Center, Palm Springs, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gelza Mae A.","family":"Zabat","sequence":"additional","affiliation":[{"name":"Health Cube Medical Clinics, Philippines, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Mo","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7502-9225","authenticated-orcid":true,"given":"Po-Ren","family":"Hsueh","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung, Taiwan"},{"name":"Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/377612"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.11.5452-5456.2005"},{"key":"e_1_3_5_4_2","unstructured":"WHO coronavirus (COVID-19) dashboard. 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