{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:49:08Z","timestamp":1785419348767,"version":"3.56.0"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A Luminex suspension array, which had been developed for identification of\n            <jats:italic>Cryptococcus neoformans<\/jats:italic>\n            and\n            <jats:italic>Cryptococcus gattii<\/jats:italic>\n            isolates, was tested by genotyping a set of 58 mostly clinical isolates. All genotypes of\n            <jats:italic>C. neoformans<\/jats:italic>\n            and\n            <jats:italic>C. gattii<\/jats:italic>\n            were included. In addition, cerebrospinal fluid (CSF) obtained from patients with cryptococcal meningitis was used to investigate the feasibility of the technique for identification of the infecting strain. The suspension array correctly identified haploid isolates in all cases. Furthermore, hybrid isolates possessing two alleles of the Luminex probe region could be identified as hybrids. In CSF specimens, the genotype of the cryptococcal strains responsible for infection could be identified after optimization of the PCR conditions. However, further optimization of the DNA extraction protocol is needed to enhance the usability of the method in clinical practice.\n          <\/jats:p>","DOI":"10.1128\/jcm.00223-07","type":"journal-article","created":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T00:53:59Z","timestamp":1176944039000},"page":"1874-1883","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":52,"title":["Identification of Genotypically Diverse\n            <i>Cryptococcus neoformans<\/i>\n            and\n            <i>Cryptococcus gattii<\/i>\n            Isolates by Luminex xMAP Technology"],"prefix":"10.1128","volume":"45","author":[{"given":"M.","family":"Bovers","sequence":"first","affiliation":[{"name":"CBS\u2014Fungal Biodiversity Centre, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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