{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T19:36:52Z","timestamp":1789414612534,"version":"build-2803163510"},"reference-count":28,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T00:00:00Z","timestamp":1590451200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2020,5,26]]},"abstract":"<jats:p>\n            Compared to its predecessor QuantiFERON-TB Gold In Tube (QFT-IT), QuantiFERON-TB Gold Plus (QFT-Plus) contains an additional antigen tube (TB2), stimulating both CD4\n            <jats:sup>+<\/jats:sup>\n            and CD8\n            <jats:sup>+<\/jats:sup>\n            T cells. The ability to discriminate CD4\n            <jats:sup>+<\/jats:sup>\n            and CD8\n            <jats:sup>+<\/jats:sup>\n            responses is suggested to be useful in differentiating stages of\n            <jats:named-content content-type=\"genus-species\">Mycobacterium tuberculosis<\/jats:named-content>\n            infection. While QFT-Plus has already been evaluated in adults, there are not enough data in children evaluated for suspected active tuberculosis (TB) or latent TB infection (LTBI).\n          <\/jats:p>","DOI":"10.1128\/jcm.00272-20","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T13:30:15Z","timestamp":1585661415000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Accuracy of QuantiFERON-TB Gold Plus Test for Diagnosis of Mycobacterium tuberculosis Infection in Children"],"prefix":"10.1128","volume":"58","author":[{"given":"Danilo","family":"Buonsenso","sequence":"first","affiliation":[{"name":"Scienze della salute della donna, del bambino e di sanit\u00e0 pubblica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0182-8267","authenticated-orcid":false,"given":"Giovanni","family":"Delogu","sequence":"additional","affiliation":[{"name":"Istituto di Microbiologia, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"},{"name":"Mater Olbia Hospital, Olbia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clelia","family":"Perricone","sequence":"additional","affiliation":[{"name":"Scienze della salute della donna, del bambino e di sanit\u00e0 pubblica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Grossi","sequence":"additional","affiliation":[{"name":"Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. 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