{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:26:52Z","timestamp":1760016412668},"reference-count":21,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Although venipuncture is the preferred method for obtaining blood cultures, specimens often are obtained from intravenous catheters (IVC). For IVC-drawn blood cultures, some authorities recommend discarding the initial 5 to 10 ml of blood to reduce contamination and remove potential inhibitory substances. To determine whether this practice reduced contamination rates (CR), we assessed the results of IVC-drawn blood cultures for adults. Thirty milliliters of blood was obtained aseptically. The first 10 ml, rather than being discarded, was inoculated into an aerobic culture vial. Using a second sterile syringe, 20 ml of blood was obtained and inoculated in 10-ml aliquots to aerobic and anaerobic culture vials. Positive cultures were evaluated to assess clinical significance (true versus contaminant). Out of 653 IVC-drawn blood culture pairs, both vials were contaminated in 38 pairs (5.8%); only the \u201cdiscard\u201d vial was contaminated in 33 (5.1%); and only the \u201cstandard\u201d vial was contaminated in 31 (4.7%). Overall CR were 10.9% for the discard vial versus 10.5% for the standard vial (\n            <jats:italic>P<\/jats:italic>\n            = 0.90). We conclude that discarding an initial aliquot of blood when obtaining blood cultures from IVCs does not reduce CR.\n          <\/jats:p>","DOI":"10.1128\/jcm.00292-09","type":"journal-article","created":{"date-parts":[[2009,7,30]],"date-time":"2009-07-30T01:28:53Z","timestamp":1248917333000},"page":"2950-2951","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Discarding the Initial Aliquot of Blood Does Not Reduce Contamination Rates in Intravenous-Catheter-Drawn Blood Cultures"],"prefix":"10.1128","volume":"47","author":[{"given":"Sukrut","family":"Dwivedi","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Allergy &amp; Immunology, Departments of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Bhalla","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Allergy &amp; Immunology, Departments of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald R.","family":"Hoover","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Allergy &amp; Immunology, Departments of Medicine"},{"name":"Department of Statistics and Biostatistics, Rutgers University, New Brunswick, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melvin P.","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Allergy &amp; Immunology, Departments of Medicine"},{"name":"Pathology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","first-page":"2006","volume":"21","year":"2006","unstructured":"Baron, E. 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