{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T07:27:34Z","timestamp":1790148454476,"version":"4.0.1"},"reference-count":41,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2016,7,25]],"date-time":"2016-07-25T00:00:00Z","timestamp":1469404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["104992"],"award-info":[{"award-number":["104992"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["087622"],"award-info":[{"award-number":["087622"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Rapid low-cost whole-genome sequencing (WGS) is revolutionizing microbiology; however, complementary advances in accessible, reproducible, and rapid analysis techniques are required to realize the potential of these data. Here, investigations of the genus\n                    <jats:named-content content-type=\"genus-species\">Neisseria<\/jats:named-content>\n                    illustrated the gene-by-gene conceptual approach to the organization and analysis of WGS data. Using the gene and its link to phenotype as a starting point, the BIGSdb database, which powers the PubMLST databases, enables the assembly of large open-access collections of annotated genomes that provide insight into the evolution of the\n                    <jats:named-content content-type=\"genus-species\">Neisseria<\/jats:named-content>\n                    , the epidemiology of meningococcal and gonococcal disease, and mechanisms of\n                    <jats:named-content content-type=\"genus-species\">Neisseria<\/jats:named-content>\n                    pathogenicity.\n                  <\/jats:p>","DOI":"10.1128\/jcm.00301-16","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T01:44:33Z","timestamp":1461203073000},"page":"1949-1955","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":45,"title":["Population and Functional Genomics of Neisseria Revealed with Gene-by-Gene Approaches"],"prefix":"10.1128","volume":"54","author":[{"given":"Martin C. J.","family":"Maiden","sequence":"first","affiliation":[{"name":"Department of Zoology, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile B.","family":"Harrison","sequence":"additional","affiliation":[{"name":"Department of Zoology, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001920"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-11-595"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.6.3140"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.59.030804.121325"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3093"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.12.62"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-15-1138"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.056077-0"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00267-4"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.055459-0"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01312-12"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-30197-1_241"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.052431-0"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.041731-0"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02124646"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03529-13"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv211"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-11-652"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011835"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-7-128"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2006.00056.x"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.18.04.20379-en"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir466"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61612-8"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7007-5-35"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02233-10"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00040-10"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1086\/383047"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01453-07"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.007641-0"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.029694"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.18.03.20358-en"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1904.111799"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03524-14"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2015.01.004"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2015.07.007"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045349"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2015.20.49.30084"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70693-5"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.806"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2015.01.004"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00301-16","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00301-16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T03:55:35Z","timestamp":1646452535000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.00301-16"}},"subtitle":[],"editor":[{"given":"C. S.","family":"Kraft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":41,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1128\/JCM.00301-16"],"URL":"https:\/\/doi.org\/10.1128\/jcm.00301-16","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.726304139.793534144","asserted-by":"object"}]},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"2016-07-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}