{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T11:42:25Z","timestamp":1791114145624,"version":"4.1.0"},"reference-count":34,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            This report describes the molecular epidemiology, in vitro susceptibility, colonial and microscopic morphologies, and biochemical features of\n            <jats:italic>Trichosporon mycotoxinivorans<\/jats:italic>\n            , a newly recognized pathogen that appears to have a propensity for patients with cystic fibrosis. The index patient died with histologically documented\n            <jats:italic>Trichosporon<\/jats:italic>\n            pneumonia complicating cystic fibrosis. This is also the first report of disease caused by a\n            <jats:italic>Trichosporon<\/jats:italic>\n            species in a nontransplant patient with cystic fibrosis. As\n            <jats:italic>T. mycotoxinivorans<\/jats:italic>\n            has not previously been recognized as a respiratory pathogen, the significance of its recovery from sputum samples was not initially appreciated. Genetic analysis of archived clinical samples found three additional cases of\n            <jats:italic>T. mycotoxinivorans<\/jats:italic>\n            infection which had previously been identified as other members of the genus. An additional isolate of\n            <jats:italic>T. mycotoxinivorans<\/jats:italic>\n            was identified from a clinical sample on initial testing. Three of these four cases were also patients with cystic fibrosis. All isolates had MICs at 48 h of amphotericin B of \u22651 \u03bcg\/ml and of echinocandins of \u226516 \u03bcg\/ml, but they displayed various susceptibilities to the triazoles. In summary,\n            <jats:italic>Trichosporon mycotoxinivorans<\/jats:italic>\n            is a newly recognized human pathogen that is associated with cystic fibrosis.\n          <\/jats:p>","DOI":"10.1128\/jcm.00460-09","type":"journal-article","created":{"date-parts":[[2009,8,6]],"date-time":"2009-08-06T01:10:45Z","timestamp":1249521045000},"page":"3091-3097","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":72,"title":["<i>Trichosporon mycotoxinivorans<\/i>\n            , a Novel Respiratory Pathogen in Patients with Cystic Fibrosis"],"prefix":"10.1128","volume":"47","author":[{"given":"Patrick W.","family":"Hickey","sequence":"first","affiliation":[{"name":"Division of Pediatric Infectious Disease"},{"name":"Departments of Pediatrics and Preventive Medicine &amp; Biometrics, Uniformed Services University, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deanna A.","family":"Sutton","sequence":"additional","affiliation":[{"name":"Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette W.","family":"Fothergill","sequence":"additional","affiliation":[{"name":"Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian L.","family":"Wickes","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University of Texas Health Science Center, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard J.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology, Walter Reed Army Medical Center, Washington, DC"},{"name":"Division of Pediatric Pulmonology, Virginia Commonwealth University, Richmond, Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Walsh","sequence":"additional","affiliation":[{"name":"National Cancer Institute, Pediatric Oncology Branch, Immunocompromised Host Section, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/15.5.781"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mph.0000164865.70522.d7"},{"key":"e_1_3_2_4_2","unstructured":"Basidiomycetous yeasts 2003"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/314727"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00208-06"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/322640"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702231"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.4.1818-1828.2005"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00713937"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1994.tb00277.x"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00713938"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2006.01223.x"},{"key":"e_1_3_2_15_2","first-page":"725","volume":"127","year":"1983","unstructured":"Knudson, R. 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