{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:37:03Z","timestamp":1791387423561,"version":"4.3.3"},"reference-count":23,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Patients presenting to the emergency department (ED) represent a heterogeneous population comprised of all ages, various backgrounds, such as from the community and skilled-nursing facilities (SNFs), and at various risks for resistant pathogens. The aim of this study was to compare patient group-specific urinary antibiograms in the ED. Adults presented to the ED with an ICD 9\/10 code urinary tract infection (UTI) diagnosis during July 2015 to June 2016 were randomly selected (\n            <jats:italic>n<\/jats:italic>\n            = 500) to extract relevant demographic, laboratory, and clinical data from the medical record. Urinary\n            <jats:named-content content-type=\"genus-species\">Escherichia coli<\/jats:named-content>\n            antibiograms were compared between institutional versus ED and among ED patients (male versus female; age of 18 to 64 years versus \u226565 years; female aged 18 to 50 years versus &gt;50 years; home versus SNF; and admitted versus discharged).\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            grew from 56% (145\/259) of the positive urine cultures. Overall ciprofloxacin (CIP), trimethoprim-sulfamethoxazole (SXT), and cefazolin (CFZ) susceptibilities were &lt;71%. Differences in antibiograms were the following: lower CFZ and SXT susceptibilities in ED versus institutional (CFZ, 67% versus 86% [\n            <jats:italic>P<\/jats:italic>\n            = 0.001]; SXT, 66% versus 74% [\n            <jats:italic>P<\/jats:italic>\n            = 0.02]), lower ampicillin and gentamicin susceptibilities in females aged 18 to 50 years versus &gt;50 years (32% versus 52% [\n            <jats:italic>P<\/jats:italic>\n            = 0.04]; 78% versus 93% [\n            <jats:italic>P<\/jats:italic>\n            = 0.02]), lower CIP susceptibilities in the elderly (64% versus 81%;\n            <jats:italic>P<\/jats:italic>\n            = 0.03), SNF versus home (35% versus 77%;\n            <jats:italic>P<\/jats:italic>\n            &lt; 0.001), admitted versus discharged (63% versus 78%;\n            <jats:italic>P<\/jats:italic>\n            = 0.04), and lower SXT susceptibilities in patients aged &lt;65 years versus the elderly (58% versus 71%;\n            <jats:italic>P<\/jats:italic>\n            = 0.01). Nitrofurantoin showed &gt;80% susceptibility in all groups. Patient group-specific urinary antibiograms revealed distinct differences in\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            susceptibility and should be developed to better inform empirical UTI therapy selection in the ED.\n          <\/jats:p>","DOI":"10.1128\/jcm.00481-17","type":"journal-article","created":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T00:40:24Z","timestamp":1497487224000},"page":"2629-2636","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":30,"title":["Emergency Department Urinary Antibiograms Differ by Specific Patient Group"],"prefix":"10.1128","volume":"55","author":[{"given":"S.","family":"Jorgensen","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Huntington Hospital, Pasadena, California, USA"},{"name":"University of Southern California, School of Pharmacy, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Zurayk","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Huntington Hospital, Pasadena, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Yeung","sequence":"additional","affiliation":[{"name":"University of Southern California, School of Pharmacy, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Terry","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Huntington Hospital, Pasadena, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dunn","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, Department of Medicine, Huntington Hospital, Pasadena, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Nieberg","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Huntington Hospital, Pasadena, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Wong-Beringer","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Huntington Hospital, Pasadena, California, USA"},{"name":"University of Southern California, School of Pharmacy, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","volume-title":"Emergency department summary tables","author":"Rui P","year":"2013","unstructured":"Rui P Kang K Albert M . 2013. National hospital ambulatory medical care survey. Emergency department summary tables. Centers for Disease Control and Prevention, Atlanta, GA. http:\/\/www.cdc.gov\/nchs\/data\/ahcd\/nhamcs_emergency\/2013_ed_web_tables.pdf. Accessed 25 January 2017."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dku282"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2016.04.022"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2015.283"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw118"},{"key":"e_1_3_2_7_2","volume-title":"CLSI document M100-S25","author":"CLSI","year":"2015","unstructured":"CLSI. 2015. Performance standards for antimicrobial susceptibility testing, 25th informational supplement. CLSI document M100-S25. Clinical and Laboratory Standards Institute, Wayne, PA."},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/acem.12729"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp140832"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2014.04.033"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-2-63"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2016.11.021"},{"key":"e_1_3_2_13_2","volume-title":"Guidelines on urological infections 2015","author":"Grabe M","year":"2015","unstructured":"Grabe M Bartolette R Bjerklund Johnstone TE Cai T Cek M Koves B Naber KG Pickard RS Tenke P Wagenlehner F Wullt B . 2015. Guidelines on urological infections 2015. European Association of Urology, Arnhem, The Netherlands."},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.07.045"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw396"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2010.10.027"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2012.02.025"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14857"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/382690"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13702"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1649"},{"key":"e_1_3_2_22_2","volume-title":"CLSI document M39-A4","author":"CLSI","year":"2014","unstructured":"CLSI. 2014. Analysis and presentation of cumulative antimicrobial susceptibility test data. Approved guideline, 4th ed. CLSI document M39-A4. Clinical and Laboratory Standards Institute, Wayne, PA.","edition":"4"},{"key":"e_1_3_2_23_2","unstructured":"Murphy\nP\nPhillips\nG\nHall\nA\nBrooks\nS\n. 2011. Women's health stats and facts. American Congress of Obstetricians and Gynecologists Washington DC. https:\/\/www.acog.org\/-\/media\/NewsRoom\/MediaKit.pdf."},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00481-17"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00481-17","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00481-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T08:58:56Z","timestamp":1646470736000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.00481-17"}},"subtitle":[],"editor":[{"given":"Daniel J.","family":"Diekema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1128\/JCM.00481-17"],"URL":"https:\/\/doi.org\/10.1128\/jcm.00481-17","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"2017-03-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}