{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:41:20Z","timestamp":1790692880505,"version":"4.1.0"},"reference-count":38,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2016,9,23]],"date-time":"2016-09-23T00:00:00Z","timestamp":1474588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Recent studies have demonstrated that screening and treatment for toxoplasmosis during gestation result in a decrease of vertical transmission and clinical sequelae. Early treatment was associated with improved outcomes. Thus, laboratory methods should aim for early identification of infants with congenital toxoplasmosis (CT). Diagnostic approaches should include, at least, detection of\n            <jats:named-content content-type=\"genus-species\">Toxoplasma<\/jats:named-content>\n            IgG, IgM, and IgA and a comprehensive review of maternal history, including the gestational age at which the mother was infected and treatment. Here, we review laboratory methods for the diagnosis of CT, with emphasis on serological tools. A diagnostic algorithm that takes into account maternal history is presented.\n          <\/jats:p>","DOI":"10.1128\/jcm.00487-16","type":"journal-article","created":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T04:20:23Z","timestamp":1462422023000},"page":"2448-2454","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":121,"title":["Laboratory Diagnosis of Congenital Toxoplasmosis"],"prefix":"10.1128","volume":"54","author":[{"given":"Christelle","family":"Pomares","sequence":"first","affiliation":[{"name":"Palo Alto Medical Foundation Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California, USA"},{"name":"Stanford University, Division of Infectious Diseases, Stanford, California, USA"},{"name":"INSERM U1065, Centre M\u00e9diterran\u00e9en de M\u00e9decine Mol\u00e9culaire, Toxines Microbiennes dans la Relation H\u00f4te-Pathog\u00e8nes, Nice, France"},{"name":"Service de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Nice, Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose G.","family":"Montoya","sequence":"additional","affiliation":[{"name":"Palo Alto Medical Foundation Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California, USA"},{"name":"Stanford University, Division of Infectious Diseases, Stanford, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.89.2306.226"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000200003"},{"key":"e_1_3_1_4_2","first-page":"949","volume-title":"Remington and Klein's infectious diseases of the fetus and newborn infant","author":"Peyron F","year":"2015","unstructured":"Peyron F, Wallon M, Kieffer F, Garweg JG. 2015. Toxoplasmosis, p. 949\u20131042. In Wilson CB, Nizet V, Maldonado Y, Remington JS, Klein JO (ed), Remington and Klein's infectious diseases of the fetus and newborn infant. 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