{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:41:45Z","timestamp":1773283305485,"version":"3.50.1"},"reference-count":48,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            is one of the most common pathogens in community- and hospital-associated infections and frequently causes severe and intractable infections in osteoarticular tissues.\n            <jats:italic>S. aureus<\/jats:italic>\n            isolates that are resistant to methicillin (meticillin) (MRSA isolates) and intermediately resistant to vancomycin (VISA isolates) have emerged. In this report, we described two patients, one female and one male, diagnosed with septic arthritis due to\n            <jats:italic>S. aureus<\/jats:italic>\n            infections. A total of 13 MRSA isolates were obtained from these two patients. All but one isolate belonged to the VISA group. All seven isolates from the female patient were determined to be community associated, multilocus sequence type (MLST) 59, and staphylococcal cassette chromosome\n            <jats:italic>mecA<\/jats:italic>\n            (SCC\n            <jats:italic>mec<\/jats:italic>\n            ) type IV; had direct repeat units (DRUs) of nine repeats; were\n            <jats:italic>spa<\/jats:italic>\n            type t437; and were susceptible to sulfa and quinolone antibiotics. The other six isolates, from the male patient, were determined to be hospital associated, MLST 239, and SCC\n            <jats:italic>mec<\/jats:italic>\n            type III; had DRUs of 14 repeats; were\n            <jats:italic>spa<\/jats:italic>\n            type t037; and were resistant to sulfa and quinolone antibiotics. All 13 MRSA isolates were in\n            <jats:italic>agr<\/jats:italic>\n            group I, were\n            <jats:italic>pvl<\/jats:italic>\n            negative, and showed no evidence of any association between vancomycin resistance and autolysis.\n          <\/jats:p>","DOI":"10.1128\/jcm.00539-09","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T01:46:38Z","timestamp":1253151998000},"page":"3617-3623","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":28,"title":["Molecular and Phenotypic Characteristics of Methicillin-Resistant and Vancomycin-Intermediate\n            <i>Staphylococcus aureus<\/i>\n            Isolates from Patients with Septic Arthritis"],"prefix":"10.1128","volume":"47","author":[{"given":"Wei-Yao","family":"Wang","sequence":"first","affiliation":[{"name":"Graduate Institute of Medical Science"},{"name":"Division of Infectious Disease, Da-Chien General Hospital, Miao-Li"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Yi","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Clinical Microbiology, Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzong-Shi","family":"Chiueh","sequence":"additional","affiliation":[{"name":"Division of Clinical Pathology, Department of Pathology, National Defense Medical Center and Tri-Service General Hospital, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jang-Jih","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Clinical Pathology, Department of Pathology, National Defense Medical Center and Tri-Service General Hospital, Taipei"},{"name":"Department of Laboratory Medicine, China Medical University Hospital, Taichung"},{"name":"Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-007-0285-z"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0566"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700501"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31812e62dc"},{"key":"e_1_3_2_6_2","unstructured":"Performance standards for antimicrobial disk susceptibility tests. 2009"},{"key":"e_1_3_2_7_2","unstructured":"Performance standards for antimicrobial susceptibility testing; 19th informational supplement (M100-S19). 2009"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp070747"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01573.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318133a85e"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.3.267"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1086\/342576"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.3.1008-1015.2000"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.122108599"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01586186"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043252"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.11.4060-4067.2002"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1998.5416"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.12.5442-5448.2003"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.8.593"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)07324-8"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.5.2384-2390.2005"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1086\/345955"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.5.1323-1336.2001"},{"key":"e_1_3_2_25_2","first-page":"904","year":"1963","unstructured":"Jevons, M. 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