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This study compares the sensitivities and specificities of three molecular tests, namely, the Xpert MTB\/RIF test, the Xpert Ultra (Ultra), and RealTi\n            <jats:italic>m<\/jats:italic>\n            e MTB (RT-MTB), in a high HIV prevalence setting.\n          <\/jats:p>","DOI":"10.1128\/jcm.00560-18","type":"journal-article","created":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T15:11:47Z","timestamp":1539270707000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":59,"title":["Performance of Xpert MTB\/RIF, Xpert Ultra, and Abbott RealTi\n            <i>m<\/i>\n            e MTB for Diagnosis of Pulmonary Tuberculosis in a High-HIV-Burden Setting"],"prefix":"10.1128","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9692-8748","authenticated-orcid":false,"given":"Rebecca H.","family":"Berhanu","sequence":"first","affiliation":[{"name":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"},{"name":"Clinical HIV Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anura","family":"David","sequence":"additional","affiliation":[{"name":"National Priority Program, National Health Laboratory Service, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"da Silva","sequence":"additional","affiliation":[{"name":"National Priority Program, National Health Laboratory Service, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Shearer","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"},{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Sanne","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"},{"name":"Clinical HIV Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Stevens","sequence":"additional","affiliation":[{"name":"National Priority Program, National Health Laboratory Service, Johannesburg, South Africa"},{"name":"Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907847"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009593.pub3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201101-0056OC"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70167-0"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30691-6"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00289-17"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)00100-X"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trw056"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.16.0801"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00812-17"},{"key":"e_1_3_3_12_2","unstructured":"Zar H Workman L Nicol M. 2017. Diagnosis of pulmonary tuberculosis in HIV-infected and uninfected children using Xpert MTB\/RIF Ultra poster B27. American Thoracic Society 2017 International Conference Washington DC 22 May 2017. Am J Respir Crit Car Med 195:A7610."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30474-7"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2016.09.006"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2017.03.002"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2016.02.024"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2015.11.001"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-015-2419-5"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01144-16"},{"key":"e_1_3_3_20_2","volume-title":"Systematic screening for active tuberculosis: principles and recommendations","author":"World Health Organization","year":"2013","unstructured":"World Health Organization. 2013. Systematic screening for active tuberculosis: principles and recommendations. World Health Organization, Geneva, Switzerland."},{"key":"e_1_3_3_21_2","volume-title":"South African national tuberculosis management guidelines","author":"National Department of Health Republic of South Africa","year":"2011","unstructured":"National Department of Health Republic of South Africa. 2011. South African national tuberculosis management guidelines. National Department of Health Republic of South Africa, Pretoria, South Africa."},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002472]"},{"key":"e_1_3_3_23_2","volume-title":"WHO meeting report of a technical expert consultation: non-inferiority analysis of Xpert MTB\/RIF Ultra compared to Xpert MTB\/RIF","author":"World Health Organization","year":"2017","unstructured":"World Health Organization. 2017. WHO meeting report of a technical expert consultation: non-inferiority analysis of Xpert MTB\/RIF Ultra compared to Xpert MTB\/RIF. 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