{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T03:26:58Z","timestamp":1773804418488,"version":"3.50.1"},"reference-count":40,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            In November 2011, The Rockefeller University Center for Clinical and Translational Science (CCTS), the Laboratory of Microbiology and Infectious Diseases, and Clinical Directors Network (CDN) launched a research and learning collaborative project with six community health centers in the New York City metropolitan area to determine the nature (clonal type) of community-acquired\n            <jats:named-content content-type=\"genus-species\">Staphylococcus aureus<\/jats:named-content>\n            strains causing skin and soft tissue infections (SSTIs). Between November 2011 and March 2013, wound and nasal samples from 129 patients with active SSTIs suspicious for\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            were collected and characterized by molecular typing techniques. In 63 of 129 patients, the skin wounds were infected by\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            : methicillin-resistant\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            (MRSA) was recovered from 39 wounds and methicillin-sensitive\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            (MSSA) was recovered from 24. Most\u201446 of the 63\u2013wound isolates belonged to the CC8\/Panton-Valentine leukocidin-positive (PVL\n            <jats:sup>+<\/jats:sup>\n            ) group of\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            clone USA300: 34 of these strains were MRSA and 12 were MSSA. Of the 63 patients with\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            infections, 30 were also colonized by\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            in the nares: 16 of the colonizing isolates were MRSA, and 14 were MSSA, and the majority of the colonizing isolates belonged to the USA300 clonal group. In most cases (70%), the colonizing isolate belonged to the same clonal type as the strain involved with the infection. In three of the patients, the identity of invasive and colonizing MRSA isolates was further documented by whole-genome sequencing.\n          <\/jats:p>","DOI":"10.1128\/jcm.00591-15","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T11:32:12Z","timestamp":1434022332000},"page":"2648-2658","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":31,"title":["Molecular Types of Methicillin-Resistant Staphylococcus aureus and Methicillin-Sensitive S. aureus Strains Causing Skin and Soft Tissue Infections and Nasal Colonization, Identified in Community Health Centers in New York City"],"prefix":"10.1128","volume":"53","author":[{"given":"Maria","family":"Pardos de la Gandara","sequence":"first","affiliation":[{"name":"Laboratory of Microbiology and Infectious Diseases, The Rockefeller University, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan 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