{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:48:05Z","timestamp":1791053285811,"version":"4.1.0"},"reference-count":43,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Domestic cats serve as the reservoir hosts of\n                    <jats:italic>Bartonella henselae<\/jats:italic>\n                    and may develop mild clinical symptoms or none after experimental infection. In humans,\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection can result in self-limiting cat scratch disease. However, immunocompromised patients may suffer from more-severe courses of infection or may even develop the potentially lethal disease bacillary angiomatosis. It was reasoned that cats with immunocompromising viral infections may react similarly to\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection. The aim of our study was to investigate the influence of the most important viruses known to cause immunosuppression in cats\u2014\n                    <jats:italic>Feline leukemia virus<\/jats:italic>\n                    (FeLV),\n                    <jats:italic>Feline immunodeficiency virus<\/jats:italic>\n                    (FIV), and\n                    <jats:italic>Feline panleukopenia virus<\/jats:italic>\n                    (FPV)\u2014on natural\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection in cats. Accordingly, 142 cats from animal shelters were necropsied and tested for\n                    <jats:italic>B. henselae<\/jats:italic>\n                    and concurrent infections with FeLV, FIV, or FPV by PCR and immunohistochemistry. A significant association was found between\n                    <jats:italic>B. henselae<\/jats:italic>\n                    and FeLV infections (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.00028), but not between\n                    <jats:italic>B. henselae<\/jats:italic>\n                    and FIV (\n                    <jats:italic>P<\/jats:italic>\n                    = 1.0) or FPV (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.756) infection, age (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.392), or gender (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.126). The results suggest that susceptibility to\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection is higher in cats with concurrent FeLV infections, regardless of whether the infection is latent or progressive. Histopathology and immunohistochemistry for\n                    <jats:italic>B. henselae<\/jats:italic>\n                    failed to identify lesions that could be attributed specifically to\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection. We conclude that the course of natural\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection in cats does not seem to be influenced by immunosuppressive viral infections in general but that latent FeLV infection may predispose cats to\n                    <jats:italic>B. henselae<\/jats:italic>\n                    infection or persistence.\n                  <\/jats:p>","DOI":"10.1128\/jcm.00750-10","type":"journal-article","created":{"date-parts":[[2010,7,7]],"date-time":"2010-07-07T23:10:02Z","timestamp":1278544202000},"page":"3295-3300","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":22,"title":["Does a Feline Leukemia Virus Infection Pave the Way for\n                    <i>Bartonella henselae<\/i>\n                    Infection in Cats?"],"prefix":"10.1128","volume":"48","author":[{"given":"Alexandra U.","family":"Buchmann","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathology, Freie Universitaet Berlin, Robert-von-Ostertag-Strasse 15, 14163 Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Kershaw","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Freie Universitaet Berlin, Robert-von-Ostertag-Strasse 15, 14163 Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkhard A. 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