{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:12:09Z","timestamp":1792714329009,"version":"4.5.0"},"reference-count":20,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Vibrio cholerae<\/jats:italic>O1 El Tor variant strains produced much more cholera toxin than did prototype El Tor strains. The amount of cholera toxin produced by El Tor variant strains both<jats:italic>in vitro<\/jats:italic>and<jats:italic>in vivo<\/jats:italic>was more or less equivalent to that produced by classical strains.<\/jats:p>","DOI":"10.1128\/jcm.00799-10","type":"journal-article","created":{"date-parts":[[2010,9,2]],"date-time":"2010-09-02T02:49:35Z","timestamp":1283395775000},"page":"4283-4286","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":74,"title":["Cholera Toxin Production by the El Tor Variant of<i>Vibrio cholerae<\/i>O1 Compared to Prototype El Tor and Classical Biotypes"],"prefix":"10.1128","volume":"48","author":[{"given":"J.","family":"Ghosh-Banerjee","sequence":"first","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Senoh","sequence":"additional","affiliation":[{"name":"Collaborative Research Center of Okayama University for Infectious Diseases in India, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Collaborative Research Center of Okayama University for Infectious Diseases in India, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Hamabata","sequence":"additional","affiliation":[{"name":"Research Institute, National Center for Global Health and Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Barman","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Koley","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. K.","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Ramamurthy","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Asakura","sequence":"additional","affiliation":[{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. B.","family":"Nair","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Takeda","sequence":"additional","affiliation":[{"name":"Collaborative Research Center of Okayama University for Infectious Diseases in India, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1011.040682"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"440","DOI":"10.4049\/jimmunol.96.3.440","volume":"96","year":"1966","unstructured":"Finkelstein, R. A., P. Atthasampunna, M. Chulasamaya, and P. Charunmethee. 1966. Pathogenesis of experimental cholera: biologic activities of purified procholeragen A. J. Immunol. 96 : 440-449.","journal-title":"J. Immunol."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.22.3.405-408.1985"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.8.1.48"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90792-F"},{"key":"e_1_3_2_7_2","first-page":"457","volume":"352","year":"1998","unstructured":"Kimsey, H. H., G. B. Nair, A. Ghosh, and M. K. Waldor. 1998. Diverse CTX phage and evolution of new pathogenic Vibrio cholerae. Lancet 352 : 457-458.","journal-title":"Lancet"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-48-1-51"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2008.00041.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.9.3296-3299.2002"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01304-06"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02040-08"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1988.tb01442.x"},{"key":"e_1_3_2_14_2","first-page":"695","volume":"128","year":"2008","unstructured":"Raychoudhuri, A., A. K. Mukhopadhyay, T. Ramamurthy, R. K. Nandy, Y. Takeda, and G. B. Nair. 2008. Biotyping of Vibrio cholerae O1: time to redefine the scheme. Indian J. Med. Res. 128 : 695-698.","journal-title":"Indian J. Med. Res."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1501.080543"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1406.080129"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268809990550"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1604.091493"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1502.080943"},{"key":"e_1_3_2_20_2","unstructured":"World Health Organization. 1987. Manual for laboratory investigations of acute enteric infections. World Health Organization Geneva Switzerland."},{"key":"e_1_3_2_21_2","first-page":"269","volume":"83","year":"2008","unstructured":"World Health Organization. 2008. Cholera 2007. Wkly. Epidemiol. Rec. 83 : 269-284.","journal-title":"Wkly. Epidemiol. Rec."}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00799-10","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00799-10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,3]],"date-time":"2023-06-03T03:53:20Z","timestamp":1685764400000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.00799-10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1128\/JCM.00799-10"],"URL":"https:\/\/doi.org\/10.1128\/jcm.00799-10","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"2010-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-08-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}