{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:08:57Z","timestamp":1793048937364,"version":"4.5.0"},"reference-count":61,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The direct detection of\n            <jats:named-content content-type=\"genus-species\">Aspergillus<\/jats:named-content>\n            nucleic acid in clinical specimens has the potential to improve the diagnosis of aspergillosis by offering more rapid and sensitive identification of invasive infections than is possible with traditional techniques, such as culture or histopathology. Molecular tests for\n            <jats:named-content content-type=\"genus-species\">Aspergillus<\/jats:named-content>\n            have been limited historically by lack of standardization and variable sensitivities and specificities. Recent efforts have been directed at addressing these limitations and optimizing assay performance using a variety of specimen types. This review provides a summary of standardization efforts and outlines the complexities of molecular testing for\n            <jats:named-content content-type=\"genus-species\">Aspergillus<\/jats:named-content>\n            in clinical mycology.\n          <\/jats:p>","DOI":"10.1128\/jcm.00818-16","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T01:58:43Z","timestamp":1470275923000},"page":"2655-2660","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Molecular Diagnostic Testing for Aspergillus"],"prefix":"10.1128","volume":"54","author":[{"given":"Margaret V.","family":"Powers-Fletcher","sequence":"first","affiliation":[{"name":"Department of Pathology, Clinical Microbiology Division, University of Utah, Salt Lake City, Utah, USA"},{"name":"Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly E.","family":"Hanson","sequence":"additional","affiliation":[{"name":"Department of Pathology, Clinical Microbiology Division, University of Utah, Salt Lake City, Utah, USA"},{"name":"Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, Utah, USA"},{"name":"Department of Medicine, Infectious Diseases Division, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(03)00013-0"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.3.608"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/503427"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03567-13"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/323335"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/13693780600796546"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.3114\/sim.2007.59.05"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.4.3.625-632.2005"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00425-07"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1117018109"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.simyco.2014.07.004"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01135-14"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00101-11"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00667-15"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.05026-11"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03216-14"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12749"},{"key":"e_1_3_1_20_2","first-page":"75","article-title":"Detection of Pneumocystis jirovecii and Aspergillus spp. DNA in bronchoalveolar lavage fluids by commercial real-time PCR assays: comparison with conventional diagnostic tests","volume":"38","author":"Orsi CF","year":"2015","unstructured":"Orsi CF, Bettua C, Pini P, Venturelli C, La Regina A, Morace G, Luppi M, Forghieri F, Bigliardi S, Luppi F, Codeluppi M, Girardis M, Blasi E. 2015. 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