{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:29:37Z","timestamp":1787016577587,"version":"build-2736575974"},"reference-count":48,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T00:00:00Z","timestamp":1537833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/AuthorWarrantyLicense.v1"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100006229","name":"Oak Ridge Institute for Science and Education","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006229","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Atlanta Research and Education Foundation Inc"},{"DOI":"10.13039\/100000030","name":"HHS | Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Serological diagnosis of syphilis depends on assays that detect treponemal and nontreponemal antibodies. Laboratory certification and trained personnel are needed to perform most of these tests, while high costs and long turnaround time can hinder treatment initiation or linkage to care.<\/jats:p>","DOI":"10.1128\/jcm.00832-18","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T09:24:11Z","timestamp":1531905851000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["Laboratory Evaluation of a Commercially Available Rapid Syphilis Test"],"prefix":"10.1128","volume":"56","author":[{"given":"Lara E.","family":"Pereira","sequence":"first","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"McCormick","sequence":"additional","affiliation":[{"name":"Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tandin","family":"Dorji","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongcheng","family":"Sun","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayur","family":"Shukla","sequence":"additional","affiliation":[{"name":"Atlanta Research and Education Foundation, Inc., Decatur, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Deutsch","sequence":"additional","affiliation":[{"name":"Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen N.","family":"Kersh","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yetunde F.","family":"Fakile","sequence":"additional","affiliation":[{"name":"Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"872","article-title":"Syphilis testing algorithms using treponemal tests for initial screening\u2013four laboratories, New York City, 2005\u20132006","volume":"57","author":"Centers for Disease Control and Prevention (CDC)","year":"2008","unstructured":"Centers for Disease Control and Prevention (CDC). 2008. Syphilis testing algorithms using treponemal tests for initial screening\u2013four laboratories, New York City, 2005\u20132006. MMWR Morb Mortal Wkly Rep 57:872\u2013875.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_3_2","unstructured":"Centers for Disease Control and Prevention. 2016. 2016 sexually transmitted diseases surveillance: syphilis. Centers for Disease Control and Prevention US Department of Health and Human Services Atlanta GA. https:\/\/www.cdc.gov\/std\/stats16\/syphilis.htm."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr6404a1"},{"key":"e_1_3_2_5_2","first-page":"133","article-title":"Discordant results from reverse sequence syphilis screening\u2013five laboratories, United States, 2006\u20132010","volume":"60","author":"Centers for Disease Control and Prevention","year":"2011","unstructured":"Centers for Disease Control and Prevention. 2011. Discordant results from reverse sequence syphilis screening\u2013five laboratories, United States, 2006\u20132010. MMWR Morb Mortal Wkly Rep 60:133\u2013137.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.CPJ.0000435752.17621.48"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-81-322-1774-9_5"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00681-14"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinmicnews.2014.12.001"},{"key":"e_1_3_2_10_2","first-page":"117","article-title":"Syphilis serology with lipoidal antigen: the meaning of positive reactions","volume":"64","author":"Kahn RL","year":"1972","unstructured":"Kahn RL. 1972. Syphilis serology with lipoidal antigen: the meaning of positive reactions. J Natl Med Assoc 64:117\u2013121 passim.","journal-title":"J Natl Med Assoc"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1155\/2005\/597580"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.8.1.1"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis757"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2005.015875"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2008.008104"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1086\/655832"},{"key":"e_1_3_2_17_2","first-page":"609","article-title":"Incidence of the prozone phenomenon in syphilis serology","volume":"84","author":"el-Zaatari MM","year":"1994","unstructured":"el-Zaatari MM, Martens MG, Anderson GD. 1994. Incidence of the prozone phenomenon in syphilis serology. Obstet Gynecol 84:609\u2013612.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1071\/SH11156"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7184.81256"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91107-N"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-12-353"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1258\/095646205774763207"},{"key":"e_1_3_2_23_2","volume-title":"Syphilis Health Check rapid immunochromatographic test (package insert)","author":"Syphilis Health Check","year":"2011","unstructured":"Syphilis Health Check. 2011. Syphilis Health Check rapid immunochromatographic test (package insert). Diagnostics Direct, Stone Harbor, NJ."},{"key":"e_1_3_2_24_2","unstructured":"Food and Drug Administration. 2014. FDA grants CLIA waiver expanding the availability of rapid screening test for syphilis. Food and Drug Administration Silver Spring MD. https:\/\/www.infectioncontroltoday.com\/stds\/fda-grants-clia-waiver-expanding-availability-rapid-screening-test-syphilis."},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054695"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2014.860356"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1080\/14737159.2018.1392240"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2006.024265"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000413"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14455"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70092-X"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2010.010145"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2007.029462"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.4314\/ahs.v15i2.8"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091504"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.21647"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.21783"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2006.022467"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.78.4.282"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2016-053065"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6542a5"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000498"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1177\/8755122517691308"},{"key":"e_1_3_2_44_2","unstructured":"R Core Team. 2017. R: a language and environment for statistical computing. R Foundation for Statistical Computing Vienna Austria. https:\/\/www.R-project.org\/."},{"key":"e_1_3_2_45_2","unstructured":"RStudio Team. 2018. RStudio: integrated development for R. RStudio Inc. Boston MA. http:\/\/www.rstudio.com."},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005758"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199104000-00010"},{"key":"e_1_3_2_48_2","unstructured":"Food and Drug Administration. 2007. Statistical guidance on reporting results from studies evaluating diagnostic tests\u2013guidance for industry and FDA staff. US Food and Drug Administration Silver Spring MD. https:\/\/www.fda.gov\/RegulatoryInformation\/Guidances\/ucm071148.htm."},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000036"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00832-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.00832-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T05:05:41Z","timestamp":1646456741000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.00832-18"}},"subtitle":[],"editor":[{"given":"Erik","family":"Munson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":48,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1128\/JCM.00832-18"],"URL":"https:\/\/doi.org\/10.1128\/jcm.00832-18","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"2018-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00832-18"}}