{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:22:27Z","timestamp":1761488547553},"reference-count":15,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We succeeded in stimulation of excretion of\n            <jats:italic>Strongyloides stercoralis<\/jats:italic>\n            larvae in stool by oral administration of a single dose of 400 mg albendazole to strongyloidiasis patients. This result overcame the false-negative results of stool examination due to low larval numbers. Stool samples were collected from 152 asymptomatic strongyloidiasis patients in the morning, prior to eating. After breakfast, they were given a dose of 400 mg albendazole, and stool samples were collected the following morning. Agar plate culture (APC), modified formalin-ether concentration technique (MFECT), and direct-smear (DS) methods were used to examine stool specimens within 3 h after defecation. The results before and after albendazole was taken were compared. All APCs that were positive became negative after albendazole administration, while MFECT showed a 1.4- to 18.0-fold increase in larval numbers in 97.4% (148\/152) of the samples. The DSs were positive in 3 out of 3 smears at a larval number of \u226545 larvae per g (lpg) of stool, and in 1or 2 out of 3 smears at a larval number between 35 and 44 lpg. At a larval number of &lt;35 lpg, the DS became negative. Interestingly 90.5% (19\/21) of the samples that were negative by all methods before albendazole administration became positive by MFECT after the treatment. Thus, MFECT can be effectively used for diagnosis of strongyloidiasis with prior administration of albendazole to the subject.\n          <\/jats:p>","DOI":"10.1128\/jcm.00852-10","type":"journal-article","created":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T02:28:03Z","timestamp":1284604083000},"page":"4216-4220","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":12,"title":["Albendazole Stimulates the Excretion of\n            <i>Strongyloides stercoralis<\/i>\n            Larvae in Stool Specimens and Enhances Sensitivity for Diagnosis of Strongyloidiasis"],"prefix":"10.1128","volume":"48","author":[{"given":"Witthaya","family":"Anamnart","sequence":"first","affiliation":[{"name":"Department of Medical Technology, School of Allied Health Sciences and Public Health, Walailak University, Thasala, Nakhon Si Thammarat"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attarat","family":"Pattanawongsa","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Walailak University, Thasala, Nakhon Si Thammarat"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pewpan Maleewong","family":"Intapan","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanchai","family":"Maleewong","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01613-09"},{"key":"e_1_3_2_3_2","first-page":"733","year":"1984","unstructured":"Beaver, P. C., R. C. Jung, and E. W. Cupp. 1984. Examination of specimens for parasites, p. 733-758. In P. C. Beaver, R. C. Jung, and E. W. Cupp (ed.). Clinical parasitology, 9th ed. Lea & Febiger, Philadelphia, PA.","journal-title":"Clinical parasitology"},{"key":"e_1_3_2_4_2","first-page":"169","volume":"11","year":"1996","unstructured":"Daenseekaew, W., V. Pipitgool, P. Sithithaworn, and S. Kitvatanachai. 1996. Albendazole in the treatment of uncomplicated strongyloidiasis by using the agar plate method. Srinagarind Med. J. 11 : 169-172.","journal-title":"Srinagarind Med. J."},{"key":"e_1_3_2_5_2","first-page":"51","volume":"3","year":"1961","unstructured":"Ferriolli, F., Jr. 1961. Condicoes que influema na extracao de larvas do Strongyloides stercoralis das fezes pelo metodo de Looss-Baermann modificado. Rev. Inst. Med. Trop. Sao Paulo 3 : 51-60.","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"e_1_3_2_6_2","first-page":"742","year":"1992","unstructured":"Goldsmith, R. S. 1992. 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Taylor & Francis, Philadelphia, PA.","journal-title":"Strongyloidiasis: a major roundworm infection of man."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60036-6"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.4.1932-1933.2005"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1991.45.518"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(20)30548-1"},{"key":"e_1_3_2_13_2","first-page":"735","volume":"26","year":"1995","unstructured":"Pitisuttithum, P., W. Supanaranond, and D. Chindanond. 1995. A randomized comparative study of albendazole and thiabendazole in chronic strongyloidiasis. Southeast Asian J. Trop. Med. Public Health 26 : 735-738.","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"e_1_3_2_14_2","first-page":"326","volume":"8","year":"1948","unstructured":"Ritchie, L. S. 1948. An ether sedimentation technique for routine stool examinations. Bull. U.S. Army Med. Dept. 8 : 326.","journal-title":"Bull. U.S. Army Med. 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