{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:43:43Z","timestamp":1793335423025,"version":"4.5.0"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The emerging multidrug-resistant pathogenic yeast\n                    <jats:named-content content-type=\"genus-species\">Candida auris<\/jats:named-content>\n                    represents a serious threat to global health. Unlike most other\n                    <jats:named-content content-type=\"genus-species\">Candida<\/jats:named-content>\n                    species, this organism appears to be commonly transmitted within health care facilities and causes health care-associated outbreaks. To better understand the epidemiology of this emerging pathogen, we investigated the ability of\n                    <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n                    to persist on plastic surfaces common in health care settings compared with that of\n                    <jats:named-content content-type=\"genus-species\">Candida parapsilosis<\/jats:named-content>\n                    , a species known to colonize the skin and plastics. Specifically, we compiled comparative and quantitative data essential to understanding the vehicles of spread and the ability of both species to survive and persist on plastic surfaces under controlled conditions (25\u00b0C and 57% relative humidity), such as those found in health care settings. When a test suspension of 10\n                    <jats:sup>4<\/jats:sup>\n                    cells was applied and dried on plastic surfaces,\n                    <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n                    remained viable for at least 14 days and\n                    <jats:named-content content-type=\"genus-species\">C. parapsilosis<\/jats:named-content>\n                    for at least 28 days, as measured by CFU. However, survival measured by esterase activity was higher for\n                    <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n                    than\n                    <jats:named-content content-type=\"genus-species\">C. parapsilosis<\/jats:named-content>\n                    throughout the 28-day study. Given the notable length of time\n                    <jats:named-content content-type=\"genus-species\">Candida<\/jats:named-content>\n                    species survive and persist outside their host, we developed methods to more effectively culture\n                    <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n                    from patients and their environment. Using our enrichment protocol, public health laboratories and researchers can now readily isolate\n                    <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n                    from complex microbial communities (such as patient skin, nasopharynx, and stool) as well as environmental biofilms, in order to better understand and prevent\n                    <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n                    colonization and transmission.\n                  <\/jats:p>","DOI":"10.1128\/jcm.00921-17","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T20:40:26Z","timestamp":1501101626000},"page":"2996-3005","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":488,"title":["Survival, Persistence, and Isolation of the Emerging Multidrug-Resistant Pathogenic Yeast Candida auris on a Plastic Health Care Surface"],"prefix":"10.1128","volume":"55","author":[{"given":"Rory M.","family":"Welsh","sequence":"first","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan L.","family":"Bentz","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Shams","sequence":"additional","affiliation":[{"name":"Clinical and Environmental Microbiology Branch, Division 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Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Rose","sequence":"additional","affiliation":[{"name":"Clinical and Environmental Microbiology Branch, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia P.","family":"Litvintseva","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, 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