{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T04:43:10Z","timestamp":1789879390021,"version":"4.0.1"},"reference-count":21,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Self-sampling by cervicovaginal lavage could be an attractive method to detect high-risk human papillomavirus (hr-HPV) infections to identify women with a risk of cervical precancer. The objective of our study was to use self-sampling for the first time in a cross-sectional approach to determine HPV prevalence and genotype distribution. We evaluated participants' acceptance and laboratory results from self-obtained samples versus endocervical brush samples obtained by gynecologists. To determine the sensitivity of both sampling methods in presumed high- and low-prevalence settings, two groups of women 20 to 30 years of age with (\n            <jats:italic>n<\/jats:italic>\n            = 55) and without (\n            <jats:italic>n<\/jats:italic>\n            = 101) a recent suspicious cytological smear were compared. Overall, 76% (95% confidence interval [95% CI], 65 to 88) of women with and 40% (95% CI, 30 to 49) of women without a recent suspicious cytological smear tested HPV positive. The prevalences of high-risk HPV strains were 71% (95% CI, 59 to 83) and 32% (95% CI, 22 to 41), respectively, for these two groups. The agreement for hr-HPV between the two sampling methods for women with and without suspicious cytology was 84% (\u03ba = 0.65; 95% CI, 0.44 to 0.86) and 91% (\u03ba = 0.78; 95% CI, 0.64 to 0.92), respectively. Participants rated the user-friendliness of the self-sampling method on a visual analog scale from 0 (easy) to 100 (difficult) with a median of 12. In conclusion, self-sampling by cervicovaginal lavage is a reliable method to determine hr-HPV prevalence and is well accepted by young adult females.\n          <\/jats:p>","DOI":"10.1128\/jcm.01026-11","type":"journal-article","created":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T14:08:28Z","timestamp":1312466908000},"page":"3519-3522","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":28,"title":["Cervicovaginal Self-Sampling Is a Reliable Method for Determination of Prevalence of Human Papillomavirus Genotypes in Women Aged 20 to 30 Years"],"prefix":"10.1128","volume":"49","author":[{"given":"Yvonne","family":"Deler\u00e9","sequence":"first","affiliation":[{"name":"Robert Koch Institute, Immunization Unit, DGZ-Ring 1, 13086 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Schuster","sequence":"additional","affiliation":[{"name":"Robert Koch Institute, Immunization Unit, DGZ-Ring 1, 13086 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Vartazarowa","sequence":"additional","affiliation":[{"name":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, CBF\/CCM, Clinic for Gynaecology, Hindenburgdamm 30, 12203 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"H\u00e4nsel","sequence":"additional","affiliation":[{"name":"Robert Koch Institute, Immunization Unit, DGZ-Ring 1, 13086 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingke","family":"Hagemann","sequence":"additional","affiliation":[{"name":"Gynecological Practice abts+partner, Eckernf\u00f6rder Str. 219, 24119 Kronshagen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Borchardt","sequence":"additional","affiliation":[{"name":"Gynecological Practice, Turmstra\u00dfe 46, 10551 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heike","family":"Perlitz","sequence":"additional","affiliation":[{"name":"Gynecological Practice, Bahnhofstra\u00dfe 7-9, 39340 Haldensleben, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achim","family":"Schneider","sequence":"additional","affiliation":[{"name":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, CBF\/CCM, Clinic for Gynaecology, Hindenburgdamm 30, 12203 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Reiter","sequence":"additional","affiliation":[{"name":"Robert Koch Institute, Immunization Unit, DGZ-Ring 1, 13086 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas M.","family":"Kaufmann","sequence":"additional","affiliation":[{"name":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, CBF\/CCM, Clinic for Gynaecology, Hindenburgdamm 30, 12203 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2004.12.008"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.55.4.244"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02440-05"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600688"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdh240"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2004.03.033"},{"key":"e_1_3_2_8_2","first-page":"1915","article-title":"Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions","volume":"10","author":"FUTURE II Study Group","year":"2007","unstructured":"FUTURE II Study Group. 2007. 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