{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:17:39Z","timestamp":1792174659336,"version":"4.4.0"},"reference-count":38,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T00:00:00Z","timestamp":1471996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The prevalence rates of\n            <jats:named-content content-type=\"genus-species\">Mycoplasma genitalium<\/jats:named-content>\n            infections and coinfections with other sexually transmitted organisms and the frequency of a macrolide antibiotic resistance phenotype were determined in urogenital specimens collected from female and male subjects enrolled in a multicenter clinical study in the United States. Specimens from 946 subjects seeking care from seven geographically diverse clinical sites were tested for\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            and for\n            <jats:named-content content-type=\"genus-species\">Chlamydia trachomatis<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Neisseria gonorrhoeae<\/jats:named-content>\n            , and\n            <jats:named-content content-type=\"genus-species\">Trichomonas vaginalis<\/jats:named-content>\n            . Sequencing was used to assess macrolide antibiotic resistance among\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            -positive subjects.\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            prevalence rates were 16.1% for females and 17.2% for males. Significant risk factors for\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            infections were black race, younger age, non-Hispanic ethnicity, and female symptomatic status. Female\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            infections were significantly more prevalent than\n            <jats:named-content content-type=\"genus-species\">C. trachomatis<\/jats:named-content>\n            and\n            <jats:named-content content-type=\"genus-species\">N. gonorrhoeae<\/jats:named-content>\n            infections, while the\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            infection rate in males was significantly higher than the\n            <jats:named-content content-type=\"genus-species\">N. gonorrhoeae<\/jats:named-content>\n            and\n            <jats:named-content content-type=\"genus-species\">T. vaginalis<\/jats:named-content>\n            infection rates. The macrolide-resistant phenotype was found in 50.8% of females and 42% of males. These results show a high prevalence of\n            <jats:named-content content-type=\"genus-species\">M. genitalium<\/jats:named-content>\n            single infections, a lower prevalence of coinfections with other sexually transmitted organisms, and high rates of macrolide antibiotic resistance in a diverse sample of subjects seeking care across a wide geographic area of the United States.\n          <\/jats:p>","DOI":"10.1128\/jcm.01053-16","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T04:13:23Z","timestamp":1466050403000},"page":"2278-2283","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":154,"title":["Mycoplasma genitalium Prevalence, Coinfection, and Macrolide Antibiotic Resistance Frequency in a Multicenter Clinical Study Cohort in the United States"],"prefix":"10.1128","volume":"54","author":[{"given":"Damon","family":"Getman","sequence":"first","affiliation":[{"name":"Hologic, Inc., San Diego, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Jiang","sequence":"additional","affiliation":[{"name":"Hologic, Inc., San Diego, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"O'Donnell","sequence":"additional","affiliation":[{"name":"Hologic, Inc., San Diego, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth","family":"Cohen","sequence":"additional","affiliation":[{"name":"Occidental College, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-1041-6"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ312"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.1.261-266.2003"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.2.683-692.2004"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.4.1236-1240.2006"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00553-06"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02463-15"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2005.074062"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2010.010320"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e3182040de9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e31815abac6"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e318255de03"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2006.12.005"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e3181b01948"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.035477"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e3181e8087e"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-937-2_8"},{"key":"e_1_3_2_19_2","first-page":"147","article-title":"Mycoplasma genitalium infection: current treatment options, therapeutic failure, and resistance-associated mutations","volume":"8","author":"Couldwell DL","year":"2015","unstructured":"Couldwell DL, Lewis DA. 2015. 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