{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:29:25Z","timestamp":1774121365352,"version":"3.50.1"},"reference-count":10,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            In this prospective, longitudinal study on 948 HIV-1-infected patients, subjects with an indeterminate IFN-\u03b3 (gamma interferon) release assay (IGRA) result at baseline were at significantly higher risk of developing AIDS-defining manifestations other than tuberculosis (TB) irrespective of CD4\n            <jats:sup>+<\/jats:sup>\n            T cell count. Thus, in HIV-1-infected patients with advanced quantitative CD4\n            <jats:sup>+<\/jats:sup>\n            T cell depletion, an indeterminate IGRA might indicate an additional loss of global T cell function, warranting detailed clinical evaluation and careful follow-up.\n          <\/jats:p>","DOI":"10.1128\/jcm.01054-12","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T17:07:32Z","timestamp":1337274452000},"page":"2767-2769","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Prognostic Value of Indeterminate IFN-\u03b3 Release Assay Results in HIV-1 Infection"],"prefix":"10.1128","volume":"50","author":[{"given":"Maximilian C.","family":"Aichelburg","sequence":"first","affiliation":[{"name":"Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Tittes","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Breitenecker","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Reiberger","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Kohrgruber","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Rieger","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004220"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/597351"},{"key":"e_1_3_2_4_2","volume-title":"Package insert.","author":"Cellestis","year":"2003","unstructured":"Cellestis. 2003. 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