{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T16:25:26Z","timestamp":1788625526769,"version":"build-2803163510"},"reference-count":19,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T00:00:00Z","timestamp":1516752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Cepheid, Sunnyvale, CA"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Trichomoniasis is the most prevalent curable sexually transmitted disease (STD). It has been associated with preterm birth and the acquisition and transmission of HIV. Recently, nucleic acid amplification tests (NAAT) have been FDA cleared in the United States for detection of\n                    <jats:named-content content-type=\"genus-species\">Trichomonas vaginalis<\/jats:named-content>\n                    in specimens from both women and men. This study reports the results of a multicenter study recently conducted using the Xpert TV (\n                    <jats:named-content content-type=\"genus-species\">T. vaginalis<\/jats:named-content>\n                    ) assay to test specimens from both men and women. On-demand results were available in as little as 40 min for positive specimens. A total of 1,867 women and 4,791 men were eligible for inclusion in the analysis. In women, the performance of the Xpert TV assay was compared to the patient infected status (PIS) derived from the results of InPouch TV broth culture and Aptima NAAT for\n                    <jats:named-content content-type=\"genus-species\">T. vaginalis<\/jats:named-content>\n                    . The diagnostic sensitivities and specificities of the Xpert TV assay for the combined female specimens (urine samples, self-collected vaginal swabs, and endocervical swabs) ranged from 99.5 to 100% and 99.4 to 99.9%, respectively. For male urine samples, the diagnostic sensitivity and specificity were 97.2% and 99.9%, respectively, compared to PIS results derived from the results of broth culture for\n                    <jats:named-content content-type=\"genus-species\">T. vaginalis<\/jats:named-content>\n                    and bidirectional gene sequencing of amplicons. Excellent performance characteristics were seen using both female and male specimens. The ease of using the Xpert TV assay should result in opportunities for enhanced screening for\n                    <jats:named-content content-type=\"genus-species\">T. vaginalis<\/jats:named-content>\n                    in both men and women and, hopefully, improved control of this infection.\n                  <\/jats:p>","DOI":"10.1128\/jcm.01091-17","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T11:30:42Z","timestamp":1511350242000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":51,"title":["Clinical Evaluation of the Cepheid Xpert TV Assay for Detection of Trichomonas vaginalis with Prospectively Collected Specimens from Men and Women"],"prefix":"10.1128","volume":"56","author":[{"given":"Jane R.","family":"Schwebke","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. A.","family":"Gaydos","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Davis","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine, Indianapolis, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Marrazzo","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Furgerson","sequence":"additional","affiliation":[{"name":"Planned Parenthood Mar Monte, San Jose, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. N.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Smith","sequence":"additional","affiliation":[{"name":"Planned Parenthood Gulf Coast, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. H.","family":"Bachmann","sequence":"additional","affiliation":[{"name":"Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Ackerman","sequence":"additional","affiliation":[{"name":"Comprehensive Clinical Trials, W. Palm Beach, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Spurrell","sequence":"additional","affiliation":[{"name":"Planned Parenthood of Southern New England, New Haven, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Ferris","sequence":"additional","affiliation":[{"name":"Augusta University, Augusta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.-A. D.","family":"Burnham","sequence":"additional","affiliation":[{"name":"Washington University in St. Louis, St. Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Reno","sequence":"additional","affiliation":[{"name":"Washington University in St. Louis, St. Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Lebed","sequence":"additional","affiliation":[{"name":"Planned Parenthood Southeastern PA, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"Planned Parenthood St. Louis Region, St. Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Kerndt","sequence":"additional","affiliation":[{"name":"University of Southern California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Philip","sequence":"additional","affiliation":[{"name":"San Francisco Public Health, San Francisco, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Jordan","sequence":"additional","affiliation":[{"name":"George Washington University School of Public Health, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Quigley","sequence":"additional","affiliation":[{"name":"Geneuity, Maryville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e318286bb53"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr6404a1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1989.03420040109029"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/376558"},{"key":"e_1_3_2_6_2","first-page":"85","article-title":"Frequency of Trichomonas vaginalis infection in couples with fertility problems","volume":"54","author":"Rivero LR","year":"2002","unstructured":"Rivero LR, Pena MR, Perez CS, Monroy SP, Sariego Ramos I, Nodarse JF. 2002. Frequency of Trichomonas vaginalis infection in couples with fertility problems. Rev Cubana Med Trop 54:85\u201390. (In Spanish.)","journal-title":"Rev Cubana Med Trop"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199707000-00008"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir747"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e3181cfcc4b"},{"key":"e_1_3_2_10_2","first-page":"149","article-title":"An evaluation of an InPouch TV culture method for diagnosing Trichomonas vaginalis infection","volume":"67","author":"Borchardt K","year":"1991","unstructured":"Borchardt K, Smith R. 1991. An evaluation of an InPouch TV culture method for diagnosing Trichomonas vaginalis infection. Genitourin Med 67:149\u2013152.","journal-title":"Genitourin Med"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.7.2940-2943.2004"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01291-11"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03461-12"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00748-12"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu446"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199305000-00003"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2012-050889"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-145-8-200610170-00005"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02966-13"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02006-13"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01091-17","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01091-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T05:11:34Z","timestamp":1646457094000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.01091-17"}},"subtitle":[],"editor":[{"given":"Michael J.","family":"Loeffelholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1128\/JCM.01091-17"],"URL":"https:\/\/doi.org\/10.1128\/jcm.01091-17","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.732150182.793565088","asserted-by":"object"}]},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"2017-07-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01091-17"}}