{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:04:45Z","timestamp":1778875485154,"version":"3.51.4"},"reference-count":25,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T00:00:00Z","timestamp":1580169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2020,1,28]]},"abstract":"<jats:p>Determining whether and when multiplex nucleic acid amplification tests (NAATs) for respiratory viruses should be repeated is difficult. We analyzed 5\u2009years of results for a multiplex NAAT targeting 14 respiratory viruses, to determine how often repeat tests were ordered and the time period in which results were likely to change. Results for NAATs performed on nasopharyngeal specimens and repeated within 90\u2009days after initial testing were analyzed.<\/jats:p>","DOI":"10.1128\/jcm.01203-19","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T13:28:39Z","timestamp":1574170119000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Optimal Timing of Repeat Multiplex Molecular Testing for Respiratory Viruses"],"prefix":"10.1128","volume":"58","author":[{"given":"Yamini","family":"Mandelia","sequence":"first","affiliation":[{"name":"Center for Pediatric Infectious Diseases, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary W.","family":"Procop","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra S.","family":"Richter","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Worley","sequence":"additional","affiliation":[{"name":"Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Esper","sequence":"additional","affiliation":[{"name":"Center for Pediatric Infectious Diseases, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.4.487"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0095-4543(05)70355-9"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1500245"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1405870"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00042-18"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03368-12"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.6.1579-1581.1997"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00382-15"},{"key":"e_1_3_3_10_2","volume-title":"Multiplex assays market by product (consumables, instruments), type (nucleic acid, protein, cell), technology (flow cytometry, luminescence), application (R&D, diagnosis), end user (pharma & biotech, reference laboratory, hospital): global forecast to 2023","author":"MarketsandMarkets","year":"2018","unstructured":"MarketsandMarkets. 2018. Multiplex assays market by product (consumables, instruments), type (nucleic acid, protein, cell), technology (flow cytometry, luminescence), application (R&D, diagnosis), end user (pharma & biotech, reference laboratory, hospital): global forecast to 2023. MarketsandMarkets, Chicago, IL. https:\/\/www.marketsandmarkets.com\/Market-Reports\/multiplex-assays-market-61593314.html."},{"key":"e_1_3_3_11_2","volume-title":"Nucleic acid based tests","author":"U.S. Food and Drug Administration","year":"2019","unstructured":"U.S. Food and Drug Administration. 2019. Nucleic acid based tests. U.S. Food and Drug Administration, Silver Spring, MD. https:\/\/www.fda.gov\/medical-devices\/vitro-diagnostics\/nucleic-acid-based-tests."},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00556-09"},{"key":"e_1_3_3_13_2","volume-title":"Medicare payments for clinical diagnostic laboratory tests in 2016: year 3 of baseline data","author":"Office of Inspector General, U.S. Department of Health and Human Services","year":"2017","unstructured":"Office of Inspector General, U.S. Department of Health and Human Services. 2017. Medicare payments for clinical diagnostic laboratory tests in 2016: year 3 of baseline data. Report OEI-09\u201317-00140. U.S. Department of Health and Human Services, Washington, DC."},{"key":"e_1_3_3_14_2","volume-title":"Proposed local coverage determination (LCD): MolDX: multiplex nucleic acid amplified tests for respiratory viral panels","author":"Centers for Medicare and Medicaid Services","year":"2018","unstructured":"Centers for Medicare and Medicaid Services. 2018. Proposed local coverage determination (LCD): MolDX: multiplex nucleic acid amplified tests for respiratory viral panels. Publication DL37713. Centers for Medicare and Medicaid Services, Baltimore, MD."},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172809"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.11.018"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00280-07"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir531"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/511159"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.4.1343"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3182568c67"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/497134"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPJOJ3HKEBD3TU"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.049551"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPX1HIEM4KLGNU"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00172113"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01203-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01203-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T10:40:57Z","timestamp":1646476857000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.01203-19"}},"subtitle":[],"editor":[{"given":"Yi-Wei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,1,28]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,1,28]]}},"alternative-id":["10.1128\/JCM.01203-19"],"URL":"https:\/\/doi.org\/10.1128\/jcm.01203-19","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,28]]},"assertion":[{"value":"2019-07-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01203-19"}}