{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T23:08:12Z","timestamp":1769555292384,"version":"3.49.0"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We report the isolation of thymidine-dependent small-colony variants (TD-SCVs) of\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            from unusual infection sites of patients with chronic soft tissue infection, tympanitis, bronchitis, peritonitis, and septicemia. Furthermore, we provide evidence that the essential growth factor for TD-SCVs, i.e., thymidine, and its metabolite dTMP are present in various human specimens.\n          <\/jats:p>","DOI":"10.1128\/jcm.01440-08","type":"journal-article","created":{"date-parts":[[2008,10,2]],"date-time":"2008-10-02T01:50:43Z","timestamp":1222912243000},"page":"3829-3832","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Thymidine-Dependent\n            <i>Staphylococcus aureus<\/i>\n            Small-Colony Variants: Human Pathogens That Are Relevant Not Only in Cases of Cystic Fibrosis Lung Disease"],"prefix":"10.1128","volume":"46","author":[{"given":"Silke","family":"Besier","sequence":"first","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, Hospital of Johann Wolfgang Goethe-University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Zander","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, Hospital of Johann Wolfgang Goethe-University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekkehard","family":"Siegel","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, Hospital of Johannes Gutenberg-University, Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan H.","family":"Saum","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biosciences, University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus-Peter","family":"Hunfeld","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, Hospital of Johann Wolfgang Goethe-University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annabelle","family":"Ehrhart","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, Hospital of Johann Wolfgang Goethe-University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volker","family":"Brade","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, Hospital of Johann Wolfgang Goethe-University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Wichelhaus","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, Hospital of Johann Wolfgang Goethe-University, Frankfurt\/Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2007.02.003"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01510-06"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01395-07"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00912-07"},{"key":"e_1_3_2_6_2","unstructured":"formance standards for antimicrobial susceptibility testing; 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