{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:05:09Z","timestamp":1790280309217,"version":"4.1.0"},"reference-count":16,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Acanthamoeba is the causative agent of granulomatous amebic encephalitis, a rare and usually fatal disease. We report a child with acute lymphoblastic leukemia who developed brain abscesses caused by\n            <jats:italic>Acanthamoeba<\/jats:italic>\n            during induction therapy. Multimodal antimicrobial chemotherapy and hyperbaric oxygen therapy resulted in complete resolution of symptoms and of pathology as seen by magnetic resonance imaging.\n          <\/jats:p>","DOI":"10.1128\/jcm.01456-10","type":"journal-article","created":{"date-parts":[[2010,11,18]],"date-time":"2010-11-18T03:32:17Z","timestamp":1290051137000},"page":"446-448","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Granulomatous Amebic Encephalitis in a Child with Acute Lymphoblastic Leukemia Successfully Treated with Multimodal Antimicrobial Therapy and Hyperbaric Oxygen"],"prefix":"10.1128","volume":"49","author":[{"given":"P.","family":"Maritschnegg","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sovinz","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Lackner","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Benesch","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Nebl","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Schwinger","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Walochnik","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Urban","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"crossref","unstructured":"Castellano-Sanchez A. et al. 2003. Acanthamoeba castellani encephalitis following partially mismatched related donor peripheral stem cell transplantation. Transpl. Infect. Dis. 5 : 191-194.","DOI":"10.1111\/j.1399-3062.2003.00029.x"},{"key":"e_1_3_1_3_2","doi-asserted-by":"crossref","unstructured":"Fung K. T. et al. 2008. Cure of Acanthamoeba cerebral abscess in a liver transplant patient. Liver Transpl. 14 : 308-312.","DOI":"10.1002\/lt.21409"},{"key":"e_1_3_1_4_2","doi-asserted-by":"crossref","unstructured":"Gast R. J. D. R. Ledee P. A. Fuerst and T. J. Byers. 1996. Subgenus systematics of Acanthamoeba: four nuclear 18S rDNA sequence types. J. Eukaryot. Microbiol. 43 : 498-504.","DOI":"10.1111\/j.1550-7408.1996.tb04510.x"},{"key":"e_1_3_1_5_2","doi-asserted-by":"crossref","unstructured":"Gupta D. G. S. Panda and S. Bakhshi. 2008. Successful treatment of acanthamoeba meningoencephalitis during induction therapy of childhood acute lymphoblastic leukemia. Pediatr. 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