{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:24:01Z","timestamp":1791239041248,"version":"4.1.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:italic>Cryptococcus gattii<\/jats:italic>\n            emerged in North America in 1999 as a human and veterinary pathogen on Vancouver Island, British Columbia. The emergent subtype, VGIIa, and the closely related subtype VGIIb can now be found in the United States in Washington, Oregon, and California. We performed multilocus sequence typing and antifungal susceptibility testing on 43 isolates of\n            <jats:italic>C. gattii<\/jats:italic>\n            from human patients in Oregon, Washington, California, and Idaho. In contrast to Vancouver Island, VGIIa was the most frequent but not the predominant subtype in the northwest United States. Antifungal susceptibility testing showed statistically significant differences in MICs between the subtypes. This is the first study to apply antifungal susceptibility testing to\n            <jats:italic>C. gattii<\/jats:italic>\n            isolates from the Pacific Northwest and the first to make direct comparisons between subtypes.\n          <\/jats:p>","DOI":"10.1128\/jcm.01505-09","type":"journal-article","created":{"date-parts":[[2009,12,10]],"date-time":"2009-12-10T02:40:46Z","timestamp":1260412846000},"page":"539-544","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":88,"title":["Correlation of Genotype and\n            <i>In Vitro<\/i>\n            Susceptibilities of\n            <i>Cryptococcus gattii<\/i>\n            Strains from the Pacific Northwest of the United States"],"prefix":"10.1128","volume":"48","author":[{"given":"Naureen","family":"Iqbal","sequence":"first","affiliation":[{"name":"Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio E.","family":"DeBess","sequence":"additional","affiliation":[{"name":"Oregon Department of Human Services, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Wohrle","sequence":"additional","affiliation":[{"name":"Washington State Department of Health, Tumwater, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Sun","sequence":"additional","affiliation":[{"name":"California Department of Public Health, Sacramento, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall J.","family":"Nett","sequence":"additional","affiliation":[{"name":"Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia"},{"name":"Idaho Department of Health and Welfare, Boise, Idaho"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela M.","family":"Ahlquist","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Chiller","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn R.","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.6.1544-1548.2000"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1130-1406(08)70019-6"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.4.912-917.1996"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/597306"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/313992"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(99)00137-6"},{"key":"e_1_3_2_8_2","unstructured":"Reference method for broth dilution antifungal susceptibility testing of yeasts: approved standard 2008"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01520-05"},{"key":"e_1_3_2_10_2","first-page":"36","volume":"16","year":"1999","unstructured":"De Bedout, C., N. 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M. Aanensen, T. Boekhout, M. Cogliati, M. R. Diaz, M. C. Esposto, M. Fisher, F. Gilgado, F. Hagen, S. Kaocharoen, A. P. Litvintseva, T. G. Mitchell, S. P. Simwami, L. Trilles, M. A. Viviani, and J. Kwon-Chung. 2009. Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. Med. Mycol. 12 : 1-14.","journal-title":"Med. 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