{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T23:47:27Z","timestamp":1792280847096,"version":"4.4.0"},"reference-count":27,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T00:00:00Z","timestamp":1580169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2020,1,28]]},"abstract":"<jats:p>\n            <jats:italic>Cryptococcus<\/jats:italic>\n            species are associated with invasive fungal infections in immunosuppressed individuals. The clinical significance of low-titer cryptococcal antigen (CrAg) by lateral flow assay is frequently uncertain. We investigated the correlation of low CrAg titers with disease in an immunocompromised patient population. Patients with first-time positive CrAg results with low serum titers (\u22641:10) at two medical centers (Los Angeles, CA) from April 2014 to July 2018 were included.\n          <\/jats:p>","DOI":"10.1128\/jcm.01648-19","type":"journal-article","created":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T12:32:36Z","timestamp":1573648356000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":12,"title":["Clinical Significance of Low Serum Cryptococcal Antigen Titers by Lateral Flow Assay in Immunocompromised Patients: a Retrospective Case-Control Study"],"prefix":"10.1128","volume":"58","author":[{"given":"Erin","family":"Dizon","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonjae","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan M.","family":"Butler-Wu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary C.","family":"She","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4557-4801-3.00264-2"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30243-8"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/649858"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/592690"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0703.010302"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy567"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00536-12"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652015000700008"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40475-015-0046-y"},{"key":"e_1_3_1_11_2","volume-title":"Rapid advice: diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children","author":"World Health Organization","year":"2011","unstructured":"World Health Organization. 2011. Rapid advice: diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children. World Health Organization, Geneva, Switzerland."},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2001.130906"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-013-0165-9"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1562895"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0000000000000426"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00751-17"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1086\/524738"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ936"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.240815"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.17.1.18821"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/597262"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu937"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127117"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myz045"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0173858"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1086\/655143"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062213"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01648-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01648-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T10:40:00Z","timestamp":1646476800000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.01648-19"}},"subtitle":[],"editor":[{"given":"Geoffrey A.","family":"Land","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,1,28]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,1,28]]}},"alternative-id":["10.1128\/JCM.01648-19"],"URL":"https:\/\/doi.org\/10.1128\/jcm.01648-19","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,28]]},"assertion":[{"value":"2019-10-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01648-19"}}